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NCT ID: NCT06428474 Completed - Dental Caries Clinical Trials

Implementation of Oral Health Educational Program on Orphan Children

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Oral diseases are most prevalent among children. Orphans children are one of the most vulnerable groups to diseases especially oral diseases. Knowledge toward oral cavity and oral hygiene measures is low among this group, leading to poor practice of oral hygiene measures, which outcomes to oral diseases. Implementation of health education program orphan children who are living in orphanages is important. the aim of this study is to evaluate the effectiveness of health education program on the knowledge and practice of orphan children. 80 children were enrolled in this study from different orphanages in Alexandria, Egypt. Knowledge and practice were evaluated before and after intervention using predesigned questionnaire, and oral hygiene was evaluated using simplified oral hygiene index

NCT ID: NCT06428318 Completed - Pneumonia Clinical Trials

Diagnostic Value of the Biofire®in Community Acquired Pneumonia

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

This study aimed to determine the impact value of the BioFire FilmArray Pneumonia panel compared to conventional sputum culture in critically ill patients with pneumonia.

NCT ID: NCT06428162 Active, not recruiting - Drug Abuse Clinical Trials

An Evaluation of Healthcare Providers' Adherence to Pharmacovigilance Practices in an African Community

Start date: February 18, 2024
Phase:
Study type: Observational

Egypt's several regions-rural, mixed, and urban-were given pre-designed surveys pertaining to drug adverse events and the role of pharmacovigilance in detection and reporting. The three sections of the survey were dedicated to studying health care professionals' knowledge concerning pharmacovigilance concepts and practices, as well as demographics and people reported or not reported. The survey also asked more questions regarding adverse occurrences that were reported.

NCT ID: NCT06427759 Not yet recruiting - Arm Aesthetics Clinical Trials

Optimizing Aesthetic Outcome for Arm Contouring Surgery by Utilizing Anthropometric Measurements

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Brachioplasty is a popular plastic surgery procedure. Current and common various techniques are based on either surgeon 's sense preoperatively. A method is needed to define how much skin and soft tissue should be excised precisely, or what can be a reference point to design a brachioplasty mathematically.(1) Anthropometric reference measurements can be applied in designing arm aesthetic surgery. Classically, anthropometry binds the upper arm length with forearm circumference and upper arm circumference to make postoperative results more harmonious and natural . (2)a 2020).

NCT ID: NCT06427720 Completed - Clinical trials for Early Diagnosed Breast Cancer

LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis

Start date: September 21, 2019
Phase:
Study type: Observational

Breast cancer is a leading cause of death among women globally, with significant incidence in Egypt. It is characterized by aggressive behavior and resistance to treatment, necessitating early detection methods. Research has revealed that many cancer-related mutations are in non-coding DNA, including microRNAs (miRNAs) and long non-coding RNAs (LncRNAs). miRNAs like miR-185-3p and miR-301a, and LncRNAs such as LINC00511, are potential biomarkers for cancer diagnosis due to their roles in gene regulation and stability in circulation. This study aims to explore the diagnostic utility of these biomarkers in breast cancer.

NCT ID: NCT06427707 Not yet recruiting - Clinical trials for Intraoperative Bleeding

The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.

Start date: June 15, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

Nasal surgeries are common day case procedures. Although surgical complications are rare, bleeding decreases surgical field visibility and may cause vascular, orbital or intracranial complications in addition to failure of procedure. So, it is crucial to maintain hypotensive anaesthesia to optimize the surgical field.

NCT ID: NCT06427278 Completed - Colorectal Cancer Clinical Trials

Implication of Long Non-coding RNA CCDC144NL-AS1/Micro RNA-143-3p Axis Expression Level as Novel Signature in Colorectal Cancer

Start date: August 1, 2019
Phase:
Study type: Observational

Elucidate the role of lncRNA CCDC144NL-AS1, hsa-miR-143-3p, and HMGA2 protein as non-invasive epigenetic molecular biomarkers in liquid biopsy of CRC Egyptian patients, individually or as an interaction arm and in comparison, to the conventional protein TMs. In addition, the investigators investigated the potential role of lncRNA CCDC144NL-AS1 as a mediator for development and/or progression of the cancer phenotype as well as CRC metastasis and its relation to both hsa-miR-143-3p and HMGA2, clinically and in silico.

NCT ID: NCT06427226 Not yet recruiting - Breast Cancer Clinical Trials

Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity

Start date: June 1, 2024
Phase: Phase 2
Study type: Interventional

This is a randomized controlled clinical trial that aims to evaluate the safety and efficacy of Dapagliflozin as a cardioprotective in doxorubicin-induced cardiotoxicity in breast cancer patients.

NCT ID: NCT06427161 Completed - Clinical trials for Obstructive Sleep Apnea

Dextrose Prolotherapy Versus LLLT in Treatment of Obstructive Sleep Apnea

Start date: April 12, 2023
Phase: N/A
Study type: Interventional

This study was conducted on 26 patients with obstructive sleep apnea. The patients were divided randomly and equally into two equal groups. In group I, the patients were treated with LLLT, while in group II, the patients were treated with dextrose injection. The patients were evaluated by: Medical history utilizing sleep unit medical sheet, physical examination including: anthropometric measures, epworth sleepiness scale, and Berlin questioner, and Polysomnography

NCT ID: NCT06426979 Completed - Pregnancy Tubal Clinical Trials

Sequential Letrozole and Methotrexate Therapy Role in Treatment of Tubal Ectopic Pregnancy

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Ectopic pregnancy (EP) is a common condition involving the implantation of fertilized ovum outside the uterine cavity, accounting for 1-2% of all pregnancies. Tubal EP (TEP) is the most common and poses a significant risk to maternal life. Early diagnosis and medical treatment, such as methotrexate (MTX) and the Fallopian tube (FT), have been studied. However, the efficacy of single-dose methotrexate (SD-MTX) is questionable, and the efficacy of two-dose versus SD-MTX for medical management of EP is being evaluated. High estrogens/progesterone ratios can disrupt embryonic motility and lead to TEP.