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NCT ID: NCT00272779 Completed - HIV Infections Clinical Trials

BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and antiviral effects of atazanavir (ATV) plus ritonavir (RTV) versus a combination drug of lopinavir (LPV) plus RTV. A combination drug containing tenofovir (TDF) and emtricitabine (FTC) will also be taken by participants in both arms.

NCT ID: NCT00269516 Completed - Clinical trials for Early Stage Parkinson's Disease

SLV308 for Treatment of Patients With Early Parkinson's Disease

Start date: June 2006
Phase: Phase 3
Study type: Interventional

This study is a multicenter, randomized, double blind, parallel group study of 6 months' treatment with SLV308 administered as a monotherapy in patients with early stage PD. An open label safety extension to this study is planned as a separate protocol for patients who are willing and eligible to participate.

NCT ID: NCT00262600 Completed - Stroke Clinical Trials

Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate

Start date: December 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this trial is to demonstrate the efficacy and safety of dabigatran etexilate in patients with non-valvular atrial fibrillation for the prevention of stroke and systemic embolism.

NCT ID: NCT00261846 Completed - Clinical trials for Chronic Myeloid Leukemia

Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive Leukemias

Start date: March 2006
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label, continuous daily dosing, two-part safety and efficacy study of SKI-606 (bosutinib) in Philadelphia chromosome positive leukemias (Ph+). Part 1 is a dose-escalation study in chronic phase Chronic Myelogenous Leukemia (CML) subjects to establish the maximum tolerated dose (MTD) in this subject population. Part 2 has begun after the completion of Part 1 and after a dose has been established for the compound in chronic phase subjects. Part 2 is a study of the the efficacy of 500mg daily oral SKI-606 (bosutinib) in patients with all phases of Ph+ CML and Ph+ Acute Lymphocytic Leukemia (ALL). The protocol will test the hypotheses that oral daily dosing of bosutinib at 500 mg will attain (1) Major Cytogenetic Response (MCyR) in chronic phase CML patients and (2) Overall Hematological Response (OHR) in advanced leukemia patients. Each phase of the disease will be evaluated as a separate cohort.

NCT ID: NCT00251719 Completed - Esophagitis, Reflux Clinical Trials

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Start date: December 2005
Phase: Phase 3
Study type: Interventional

This is a study to assess the efficacy and safety of 8 weeks of treatment with Dexlansoprazole modified release (MR)(60 mg daily and 90 mg daily) compared to Lansoprazole (30 mg daily) in healing subjects with endoscopically proven erosive esophagitis.

NCT ID: NCT00245960 Completed - Psoriatic Arthritis Clinical Trials

Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic Arthritis

Start date: December 27, 2005
Phase: Phase 4
Study type: Interventional

The purpose of the study was to compare the efficacy of 2 different Etanercept regimens for the treatment of skin and joint manifestations of psoriatic arthritis.

NCT ID: NCT00244140 Completed - Diagnostic Imaging Clinical Trials

Ultravist: Safety and Efficacy in Computed Tomography of Head and Body

Start date: October 2005
Phase: Phase 3
Study type: Interventional

This is a research study involving the use of a contrast agent called Ultravist Injection. Ultravist, the study drug, is used to improve the pictures obtained using computed tomography (CT). Ultravist acts like a dye to make CT pictures brighter and easier to read. In the case of this study, it will be injected into a vein in the patient's arm; from there, it travels through the blood stream and to the areas to be examined. CT scans will then be taken of the patient's head and/or body as ordered by his/her physician. Phase IIIb Study to Document the Safety and Efficacy of Ultravist 370 mg I/ml, When Administered Intravenously, in Volumes up to 162.2 ml, for Clinically Indicated Contrast Enhanced Computed Tomography (CECT) of the Head and/or Body

NCT ID: NCT00219141 Completed - Hypertension Clinical Trials

Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension

ALLAY
Start date: October 2005
Phase: Phase 3
Study type: Interventional

To compare the efficacy and safety of aliskiren in combination with losartan compared to losartan on the regression of the increased size of the left ventricle in overweight patients with high blood pressure.

NCT ID: NCT00200837 Completed - Oral Tumors Clinical Trials

Ethnopharmacological Studies in Oral Medicine

Start date: March 2002
Phase: N/A
Study type: Observational

These are ethnomedicine studies of plants used by rural and indigenous peoples for pain and oral inflammation relief.

NCT ID: NCT00196989 Completed - Clinical trials for Diabetes Mellitus, Type 2

Study In People With Type 2 Diabetes

Start date: September 2005
Phase: Phase 2
Study type: Interventional

This Phase 2 dose-ranging study will evaluate the efficacy, safety and tolerability of a range of doses of GW677954 compared with placebo over sixteen weeks of treatment in subjects with T2DM (Type 2 Diabetes Mellitus).