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NCT ID: NCT00545740 Completed - Diverticulitis Clinical Trials

Prevention of Recurrence of Diverticulitis

PREVENT1
Start date: November 28, 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether SPD476 is effective in reducing recurrence of diverticulitis.

NCT ID: NCT00545532 Completed - Influenza, Human Clinical Trials

A Study of Oseltamivir (Tamiflu) for Treatment of Influenza in Immunocompromised Participants.

Start date: February 4, 2008
Phase: Phase 3
Study type: Interventional

This 2-arm study will investigate the safety and tolerability of oseltamivir for the treatment of influenza in immunocompromised participants and characterize the effects of oseltamivir in immunocompromised participants on the development of resistant influenza virus. Eligible immunocompromised participants with laboratory-confirmed influenza will be randomized to receive either conventional dose (30 milligrams [mg] to 75 mg twice daily orally [po], depending on age and weight) or double dose (60 mg-150 mg twice daily po depending on age and weight) olseltamivir for 10 days. Nasal and throat swabs will be taken, and safety evaluations made, at intervals during the study. The anticipated time on study medication is 10 days and the anticipated time on study is 40 days.

NCT ID: NCT00543439 Completed - Hemophilia A Clinical Trials

Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIII

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to determine the effectiveness, safety, and pharmacokinetics (PK) of moroctocog alfa (AF-CC) in previously treated subjects, who are younger than 6 years of age, with severe or moderately severe hemophilia A.

NCT ID: NCT00542308 Completed - Clinical trials for Head and Neck Cancer

Zalutumumab in Non-curable Patients With SCCHN

Start date: January 2008
Phase: Phase 2
Study type: Interventional

Treatment, In combination with BSC, Open-label, Single arm, Efficacy Study.

NCT ID: NCT00537238 Completed - Partial Seizures Clinical Trials

Pregabalin Versus Levetiracetam In Partial Seizures

Start date: October 2007
Phase: Phase 3
Study type: Interventional

This study will compare pregabalin and levetiracetam in patients with partial seizures. It will also evaluate the safety and tolerability of pregabalin and levetiracetam in these patients.

NCT ID: NCT00535132 Completed - Schizophrenia Clinical Trials

Study to Measure Drug Satisfaction of Patients With Schizophrenia After Switching From Risperidone to Paliperidone

Start date: October 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate medication satisfaction after at least 4 weeks of paliperidone ER (extended-release), an antipsychotic, treatment in patients with schizophrenia who were previously taking either 4 or 6 mg of risperidone daily by mouth, but who are not satisfied with their treatment.

NCT ID: NCT00525824 Completed - Atherosclerosis Clinical Trials

12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTORâ„¢) in Combination With Ezetimibe

GRAVITY
Start date: August 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether treatment of Rosuvastatin (CRESTORâ„¢) or Simvastatin given as monotherapy or given in combination with Ezetimibe, will lower the Low Density Lipoprotein Cholesterol (LDL-C) in patients with Hypercholesterolaemia and Coronary Heart Disease (CHD) or a CHD Risk Equivalent, Atherosclerosis or a 10-year CHD Risk of >20%

NCT ID: NCT00517413 Completed - Anemia Clinical Trials

LATINO Study: A Study of Mircera for the Maintenance Treatment of Dialysis Patients With Chronic Renal Anemia.

Start date: n/a
Phase: Phase 3
Study type: Interventional

This single arm study will assess the efficacy and safety of Mircera when administered once monthly, subcutaneously or intravenously, for the maintenance of hemoglobin levels in dialysis patients with chronic renal anemia. Patients currently receiving maintenance treatment with epoetin alfa will receive monthly injections of Mircera with a starting dose (120, 200 or 360 micrograms) derived from the dose of epoetin alfa they were receiving in the week preceding study start. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.

NCT ID: NCT00512109 Completed - Stroke Clinical Trials

Vascular Events In Noncardiac Surgery Patients Cohort Evaluation Study (VISION)

VISION
Start date: August 2007
Phase:
Study type: Observational

The investigators' study has 4 primary objectives. Among patients undergoing noncardiac surgery the investigators will determine: (1) the incidence of major perioperative vascular events; (2) the optimal clinical model to predict major perioperative vascular events; (3) the proportion of patients with perioperative myocardial infarctions that may go undetected without perioperative troponin monitoring; and (4) the relationship between postoperative troponin measurements and the 1 year risk of vascular death.

NCT ID: NCT00504543 Completed - Clinical trials for Kidney Transplantation

Efficacy, Safety and Tolerability of AEB071 Versus Cyclosporine in the Novo Renal Transplant Recipients

AEB071
Start date: July 2007
Phase: Phase 2
Study type: Interventional

This study will assess safety and efficacy of AEB071 combined with everolimus in a CNI-free (calcineurin inhibitor) regimen in renal transplant recipients.