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NCT ID: NCT06038461 Not yet recruiting - Clinical trials for Neuroendocrine Tumors

An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors

Start date: September 15, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a prospective, open, single-center study evaluating the efficacy and safety of surufatinib Combined With Temozolomide and S-1 as the first-line treatment of advanced neuroendocrine tumors

NCT ID: NCT06038058 Not yet recruiting - Clinical trials for Advanced Malignancies

A Phase I Study of BRY812 for Injection Alone in Subjects With Advanced Malignancies

Start date: October 2023
Phase: Phase 1
Study type: Interventional

This is a Phase I, multicenter, open-label, single-arm and first-in-human clinical study of BRY812 for injection. The study objectives are to evaluate the safety, tolerability, pharmacokinetic profile, anti-tumor activity and immunogenicity of BRY812 for injection in patients with advanced malignancies. Patients will receive treatment every 3 weeks until intolerable toxicity, disease progression, pregnancy, withdrawal of informed consent, death, study discontinuation, or withdrawal from the study.

NCT ID: NCT06036355 Not yet recruiting - Clinical trials for Postoperative Prevention of Tumor

The Exploratory Study on the Biological Function of Dendritic Cells In Vivo Supported by Nicotinamide Mononucleotide (Vital NAD)

Start date: September 30, 2023
Phase: Early Phase 1
Study type: Interventional

The main purpose of this study is to explore the PK/PD changes of NMN and DC cells after oral NMN combined with DC cells injection in patients after tumor surgery, and evaluate the biological age of adults, TCR diversity, SiRT1 expression level, SF-36 quality of life, OS, antigen specific immune response (TAA), cytokines and so on. In this study, 20 postoperative tumor patients who meet the entry and excretion criteria were recruited to explore the clinical potential of NMN combined with DC cell vaccine.

NCT ID: NCT06032572 Not yet recruiting - Clinical trials for Coronary Artery Disease

Evaluation of the Safety and Effectiveness of the VRS100 System in PCI (ESSENCE)

Start date: September 8, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the safety and effectiveness of the clinical and technical performance of the VRS100 system with disposable surgical kit in the delivery and manipulation of coronary guidewires and stent/balloon systems for use in percutaneous coronary interventions (PCI).

NCT ID: NCT06031896 Not yet recruiting - Clinical trials for Periodontal Diseases

The Severity of Periodontitis at the Buccal and Palatal Site

Start date: October 1, 2023
Phase:
Study type: Observational

To record and compare the periodontal conditions of buccal and palatal sites in patients

NCT ID: NCT06031545 Not yet recruiting - Clinical trials for Catheter Complications

An Exploratory Study of Perioperative Venous Access in Obese Patients

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

This study is intended to explore the application effect of long peripheral intravenous catheters(LPCs) and midline catheters(MCs) in the perioperative period of obese patients, aiming at providing the scientific basis for the optimal perioperative venous access for the obese patients.

NCT ID: NCT06031480 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Anlotinib and TQB2450 in Advanced Hepatocellular Carcinoma After Failure of Prior Immune Checkpoint Inhibitors

FAITH
Start date: October 31, 2023
Phase: Phase 2
Study type: Interventional

This is an multi-center, single arm, exploratory study to evaluate the efficacy and safety of anlitinib combined with TQB2450 in patients with advanced hepatocellular carcinoma (HCC)who failed prior immune checkpoint inhibitor therapies.

NCT ID: NCT06031012 Not yet recruiting - Mucositis Oral Clinical Trials

Glutamine Combined With Thalidomide in Preventing Radiation-induced Oral Mucositis

Start date: September 15, 2023
Phase: Phase 3
Study type: Interventional

The goal of this study is to compare glutamine combined with thalidomide with glutamine alone in preventing radiation-induced oral mucositis. The aim of this study is to answer whether glutamine plus thalidomide could improve the median incidence time of grade 2 oral mucositis. Participants would be randomly divided into the two groups above mentioned.

NCT ID: NCT06029816 Not yet recruiting - NSCLC Clinical Trials

Neratinib Tablets in the Treatment of Advanced NSCLC With Rare EGFR Mutations

CVL009-2001
Start date: November 20, 2023
Phase: Phase 2
Study type: Interventional

Single-arm, open-label, multicenter phase II clinical study

NCT ID: NCT06029608 Not yet recruiting - Clinical trials for Evaluation,Efficacy,Safety

Evaluation of the Efficacy and Safety of Magnetically-controlled Capsule Gastroscopy for Postoperative Assessment in Elderly Patients and Patients With Underlying Diseases

Start date: September 6, 2023
Phase:
Study type: Observational

The objective of this prospective, observational, controlled clinical study is to use magnetically-controlled capsule gastroscopy for postoperative assessment in elderly patients and patients with underlying diseases, to evaluate its clinical efficacy and safety.