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NCT ID: NCT05444166 Recruiting - Colonoscopy Clinical Trials

Explore the Relationship Between the Percentage of Colonoscopy Withdrawal Overspeed and the ADR

Start date: July 29, 2022
Phase:
Study type: Observational

In this study, the investigators used the optical flow method to measure the colonoscopy withdrawal speed, and doctors were selected from multiple hospitals to collect prospective colonoscopy screening videos, and the percentage of colonoscopy withdrawal overspeed was calculated to explore the relationship between it based on optical flow method and the adenoma detection rate.

NCT ID: NCT05444088 Recruiting - Clinical trials for Advanced Hepatocellular Carcinoma

Study of SHR-8068 Combined With Adebrelimab and Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma

Start date: August 2, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the tolerability and safety of SHR-8068 in combination with Adebrelimab and Bevacizumab in subjects with advanced HCC; To evaluate the efficacy of SHR-8068 in combination with Adebrelimab and Bevacizumab in subjects with advanced HCC.

NCT ID: NCT05443958 Recruiting - Epilepsy Clinical Trials

The Role of Intracranial Electroencephalography (IEEG) in the Localization of Epileptogenic Zones (EZ) and Its Relationship With Prognosis

Start date: July 1, 2022
Phase:
Study type: Observational

The mechanism of epilepsy pathogenesis is complex and not fully defined, and about 20-30% of patients with seizures that cannot be completely controlled by drugs become drug-resistant epilepsy. For focal drug-resistant epilepsy, surgical removal of the epileptogenic zone can control seizures, but the overall seizure-free rate in the long term after surgery is 60-70%, and the results are still not satisfactory. Accurate assessment of the location and extent of the epileptogenic zone and its adequate excision are prerequisites for the success or failure of surgery. Intracranial EEG (iEEG) has been shown to be the most accurate method for determining the location and boundaries of the epileptogenic zone. It can selectively record the local cortical electrical activity through intracranial electrodes and achieve high temporal resolution for long-range recording, reliably reflecting the continuous dynamic changes of EEG during interictal and ictal periods. The in-depth analysis of iEEG can improve the efficacy of epilepsy surgery and provide important information to reveal the pathogenesis of epilepsy.

NCT ID: NCT05443841 Recruiting - Esophageal Cancer Clinical Trials

Value of Pleural Lavage Cytology in Resectable Esophageal Carcinoma Eastern Cooperative Thoracic Oncology Projects 2005, ECTOP-2005)

ECTOP-2005
Start date: July 18, 2022
Phase:
Study type: Observational [Patient Registry]

Disease recurrence and metastasis are common after curative treatment for patients with esophageal cancer. Thus, it is important to identify the risk factors to predict disease recurrence and metastasis. Pleural lavage cytology (PLC) is reported to be associated with disease recurrence and patient survival in lung cancer, but the value is unclear in esophageal cancer. The aim of this study is to evaluate the value of PLC in esophageal cancer patient in terms of frequencies, association with patient survival, and efficacy of postoperative treatment.

NCT ID: NCT05443672 Recruiting - Breast Neoplasms Clinical Trials

Multi-center Study of Deep Learning AI in Breast Mass

Start date: August 12, 2021
Phase:
Study type: Observational

This multi-center study intends to evaluate the value of the detection and differential diagnosis of breast mass using deep learning AI-based real-time ultrasound examination.

NCT ID: NCT05443646 Recruiting - Clinical trials for Limited Stage Small Cell Lung Cancer

Consolidation Serplulimab Following Concurrent Chemoradiotherapy for LS-SCLC Patients

Start date: September 23, 2022
Phase: Phase 2
Study type: Interventional

This study is a multi-center, Single-arm Phase II study to evaluate the clinical efficacy and safety of Consolidation HLX10 (Serplulimab) Following Hypofractionated Radiotherapy With Concurrent Chemotherapy for Patients With Limited Stage Small Cell Lung Cancer

NCT ID: NCT05443581 Recruiting - Obesity Clinical Trials

The Effect of Vegetarian Diet on Patients With Metabolic Associated Fatty Liver Disease

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

In this study, 18-60 years old patients with metabolic associated fatty liver disease(MAFLD) will be recruited to test the intervention effect of vegetarian diet. This randomized clinical trial randomized individuals to a healthy vegetarian diet or a healthy omnivorous diet for 24 weeks. At the baseline and after the 24week intervention, the clinical manifestations of MAFLD, obesity levels, indices for glucose and lipid metabolism parameters, results of questionnaire and fecal samples will be collected and analyzed.

NCT ID: NCT05442827 Recruiting - Clinical trials for Uterine Fibroids With Menorrhagia

A Phase II/III Study of Efficacy and Safety of SHR7280 Tablets in Subjects With Menorrhagia With Uterine Fibroids

Start date: September 10, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Phase II:To explore the optimal effective dose of SHR7280 tablets in subjects with menorrhagia with uterine fibroids as a phase III treatment dose. Phase III:To evaluate the efficacy of the selected dose of SHR7280 compared with placebo in reducing menstrual bleeding in subjects with menorrhagic uterine fibroids in phase II studies.

NCT ID: NCT05442632 Recruiting - Hepatopathy Clinical Trials

Efficacy and Safety of Herombopag in Patients With Thrombocytopenia Before Hepatectomy

Start date: July 25, 2022
Phase: Phase 2
Study type: Interventional

This is a single center, randomized, controlled study, to evaluate the efficacy and safety of Herombopag in patients with Thrombocytopenia before hepatectomy.

NCT ID: NCT05442567 Recruiting - Ulcerative Colitis Clinical Trials

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Start date: May 16, 2023
Phase: Phase 3
Study type: Interventional

The study is an extension of two parent studies (MLN0002-3024 [NCT04779307] and MLN0002-3025 [NCT04779320]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.