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NCT ID: NCT06086912 Completed - Type 2 Diabetes Clinical Trials

A Clinical Study to Compare the Bioavailability of HR17031 in Healthy Subjects at Different Sites

Start date: November 7, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the bioavailability and safety of HR17031 injection in healthy subjects at different sites.

NCT ID: NCT06085534 Completed - Clinical trials for Ankylosing Spondylitis

A Study of LNK01001 Capsule in Patients With Ankylosing Spondylitis

Start date: January 6, 2022
Phase: Phase 2
Study type: Interventional

The objective of this study was to evaluate the safety and efficacy of multiple doses of LNK01001 monotherapy versus placebo in the treatment of adults with active Ankylosing Spondylitis

NCT ID: NCT06085521 Completed - Atopic Dermatitis Clinical Trials

A Study of LNK01001 Capsule in Patients With Moderate to Severe Atopic Dermatitis

Start date: January 26, 2022
Phase: Phase 2
Study type: Interventional

Participants who meet eligibility criteria will be randomized in a 1:1:1 ratio to receive a twice daily oral LNK01001 dose A or LNK01001 dose B or matching placebo for 12 weeks.

NCT ID: NCT06084975 Completed - Clinical trials for Distal Pancreatectomy

Comparison of Outcomes Between Warshaw and Kimura Techniques for Spleen-preserving Minimally Invasive Distal Pancreatectomy

Start date: July 1, 2018
Phase:
Study type: Observational

Spleen-persevering distal pancreatectomy (SP-DP) has been widely advocated as a routine procedure for benign or low-grade malignant tumors in the pancreatic body and tail, especially with a minimally invasive approach. Spleen preservation can be accomplished with Kimura technique (KT) or Warshaw technique (WT) Both of the two techniques were proved to be feasible and efficient. However, the perioperative outcomes and long-term benefits between patients with KT and WT in spleen-persevering minimally invasive distal pancreatectomy (SP-MIDP) remains controversial. Several small series have reported a slightly higher prevalence of postpancreatectomy hemorrhage (PPH) in patients who undergo KT than those undergo WT. The exposure of splenic vessels to erosive pancreatic juice and the preservation of splenic vessels itself may explain the higher chance of PPH in KT. Larger volume studies are warranted to confirm this finding and to clarify the clinical significance. This study compared the perioperative outcomes between the two spleen-preserving techniques, with a focus on parameters relating to perioperative patient safety. Especially, the incidence and clinical relevance of PPH in SP-MIDP were evaluated.

NCT ID: NCT06084156 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Study to Evaluate the DDI of HSK7653 With Metformin

Start date: August 10, 2019
Phase: Phase 1
Study type: Interventional

This is a Phase 1, single center, open-label, single arm, drug-drug interaction study of HSK7653 and metformin in Healthy Subjects.

NCT ID: NCT06083285 Completed - Clinical trials for To Explore the Influence of CRRT Nursing Team Management Plan on the Prognosis of SAKI Patients

Impact of the CRRT Management Protocol on Prognostic Outcome in Patients With Septic Acute Kidney Injury

Start date: February 1, 2021
Phase:
Study type: Observational

The implementation of CRRT nursing team management program in the treatment of SAKI can significantly reduce the incidence of adverse events and complications in CRRT nursing, which has a positive role in improving the success rate of CRRT treatment and the clinical outcome of patients.

NCT ID: NCT06083116 Completed - Diabetes in Adults Clinical Trials

Drug-Drug Interaction Study Between Henagliflozin Proline and Hydrochlorothiazide

Start date: August 28, 2019
Phase: Phase 1
Study type: Interventional

A single-center, single-arm, open-label, multi-dose, three-period study was conducted in healthy Chinese volunteers.

NCT ID: NCT06082986 Completed - Crohn Disease Clinical Trials

A Retrospective Observational Study of Ustekinumab Among Bio-naive Participants With Crohn's Disease in China

Start date: October 9, 2023
Phase:
Study type: Observational

Bio-naive participants are defined as the participants who previously have not received any biologics for Crohn's Disease (CD).The purpose of this retrospective study is to describe the endoscopic remission at week 24 among bio-naive participants with CD treated with ustekinumab in China.

NCT ID: NCT06082596 Completed - Clinical trials for Relapsed or Refractory Multiple Myeloma

Study of BEBT-908 in Subjects With Advanced Hematological Tumors

Start date: March 2, 2016
Phase: Phase 1
Study type: Interventional

The purpose of this study was to evaluate the safety and tolerance of BEBT-908 for injection in the treatment of recurrent refractory malignant lymphoma, multiple myeloma and chronic lymphoblastic leukemia, and to obtain the pharmacokinetic data and preliminary efficacy of BEBT-908 for injection, and to explore the relationship between the safety and efficacy of BEBT-908 for injection and related biomarkers.

NCT ID: NCT06082414 Completed - Clinical trials for Bronchopulmonary Dysplasia

Systemic Management in Extremely Preterm and Extremely Low Birth Weight Infants

Start date: January 30, 2019
Phase:
Study type: Observational

to estimate incidences of major complications, such as bronchopulmonary dysplasia, death, and delivery room resuscitation among extremely preterm and extremely low birth weight infants in Northern China