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NCT ID: NCT00673400 Completed - Rectocele Clinical Trials

Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM

STARR
Start date: January 2008
Phase: N/A
Study type: Interventional

The stapled transanal rectal resection (STARR procedure) is an effective treatment for obstructed defecation syndrome (ODS) caused by intussusception and rectocele. Recently a new technique has been developed using the new Contour® TranstarTM stapler, which was specifically designed to facilitate the STARR procedure. The investigators would like to evaluate the morbidity and quality of life.

NCT ID: NCT00673257 Completed - Clinical trials for Unspecified Childhood Solid Tumor, Protocol Specific

Pharmacokinetics of Daunorubicin in Young Patients With Cancer

Start date: January 2007
Phase: N/A
Study type: Interventional

This laboratory study is looking at the pharmacokinetics of daunorubicin in young patients with cancer. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about how patients respond to treatment with certain chemotherapy drugs.

NCT ID: NCT00673049 Terminated - Clinical trials for Carcinoma, Non-Small-Cell Lung

Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer

NSCLC
Start date: May 2008
Phase: Phase 3
Study type: Interventional

The objective of this study is to test a clinical benefit of the addition of CP 751,871 to erlotinib therapy in patients with advanced NSCLC of non adenocarcinoma histology. The primary endpoint is Overall Survival (OS).

NCT ID: NCT00672555 Completed - Pilonidal Sinus Clinical Trials

Limberg-flap: Prospective Data Collection

Start date: August 2006
Phase: N/A
Study type: Interventional

The investigators think, that the treatment of pilonidal sinus with excision and covering of the defect with a Limberg-flap is a very good treatment option. The investigators are introducing this treatment for recurrences of this illness in our clinic and want to analyse the feasibility, the results, the complications and the patients opinion after the treatment. If the results are good, a prospective randomised study is a further option.

NCT ID: NCT00671619 Completed - Healthy Clinical Trials

Study of ESBA105 Eye Drops in Healthy Subjects

Start date: April 2008
Phase: Phase 1
Study type: Interventional

Objectives: To evaluate the safety, tolerability and pharmacokinetics of ESBA105 administered topically to the eye for up to 28 days in healthy volunteers. To determine the systemic exposure to ESBA105 upon single and repeated-dose topical application to the eye in healthy volunteers.

NCT ID: NCT00669695 Terminated - Clinical trials for Obstructive Sleep Apnea Syndrome

Systemic Inflammation and Obstructive Sleep Apnea Syndrome: Effect of Atorvastatin

StatinflaSAS
Start date: May 2008
Phase: Phase 2
Study type: Interventional

The aim of this clinical trial is to evaluate the effect of Atorvastatin on the endothelial function improvement during the obstructive sleep apnea syndrome (OSAS) after 3 months of treatment, by a double-blind, randomized, placebo-controlled, multi-center study. An interim analysis will be performed when 25 patients per group will be included.

NCT ID: NCT00668070 Completed - Clinical trials for Non-Alcoholic Steatohepatitis

A Proof-of-principle Study of Oral Treatment of Non-alcoholic Steatohepatitis With a Novel PDE4 Inhibitor ASP9831

ASTER
Start date: April 2008
Phase: Phase 2
Study type: Interventional

The aim of this study is to explore the effect of a new drug (ASP9831) in patients with non-alcoholic steatohepatitis (NASH) by assessing clinical signs, laboratory data and biomarkers during a 12 week treatment period

NCT ID: NCT00667810 Terminated - Alzheimer Disease Clinical Trials

Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients

Start date: June 2008
Phase: Phase 3
Study type: Interventional

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

NCT ID: NCT00667524 Completed - Clinical trials for Eosinophilic Esophagitis

Eosinophilic Esophagitis: Influence of Dilation on Dysphagia and Inflammation

Start date: February 2008
Phase: N/A
Study type: Observational

A database analysis and review of histological slides (retrospective) and a patient questionnaire analysis (prospective) will be conducted in Bern (Switzerland) to evaluate the efficacy and safety of esophageal dilation and its effect on the underlying eosinophilic inflammation in patients with Eosinophilic Esophagitis. This trial is investigator driven.

NCT ID: NCT00663169 Completed - Arthritis, Gouty Clinical Trials

Efficacy and Safety of a Single Dose of Canakinumab (ACZ885) in Hospitalized Patients With Acute Gout

Start date: April 2008
Phase: Phase 2
Study type: Interventional

This is an exploratory proof-of-concept study to evaluate the safety and efficacy of canakinumab (ACZ885) for inflammation and pain associated with acute gouty arthritis.