Clinical Trials Logo

Filter by:
NCT ID: NCT01243073 Completed - Polycythemia Vera Clinical Trials

Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera

ET/PV
Start date: December 2010
Phase: Phase 2
Study type: Interventional

This is a phase II open-label study of single agent imetelstat in patients with essential thrombocytopenia or with polycythemia vera who have failed or are intolerant to at least one prior therapy, or who refuse standard therapy.

NCT ID: NCT01243008 Completed - Lyme Disease Clinical Trials

Safety, Skin and Plasma Concentration of Azithromycin Dermal Formulation

IXO-01
Start date: April 2010
Phase: Phase 1/Phase 2
Study type: Interventional

IXODES GmbH intends to develop SHB001, an azithromycin dermal formulation in order to prevent Lyme disease at early stages of infection after tick bite.

NCT ID: NCT01242618 Completed - Skin Carcinoma Clinical Trials

Tissue Engineered Nasal Cartilage for Reconstruction of the Alar Lobule

Start date: October 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the safety and feasibility of implanting an engineered cartilage graft, obtained by culturing expanded autologous nasal chondrocytes within a collagen type I/III membrane, in the alar lobule of patients after resection of a non melanoma skin cancer.

NCT ID: NCT01241643 Terminated - HIV Clinical Trials

Randomized Study on Multiple Cycles of Interleukin-7 in HIV Patients Immune Non-responders

Inspire 3
Start date: September 2010
Phase: Phase 2
Study type: Interventional

This is a Phase II multicenter, open-labeled, controlled, randomized study assessing weekly doses of Interleukin-7 (CYT107)

NCT ID: NCT01241591 Completed - Psoriasis Clinical Trials

A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study Of The Efficacy And Safety Comparing CP- 690,550 And Etanercept In Subjects With Moderate To Severe Chronic Plaque Psoriasis

Start date: November 2010
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of CP-690,550 as compared to etanercept and the safety of CP-690,550 for treatment of moderate to severe chronic plaque psoriasis.

NCT ID: NCT01239797 Completed - Multiple Myeloma Clinical Trials

Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Relapsed or Refractory Multiple Myeloma

ELOQUENT - 2
Start date: June 20, 2011
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether the addition of Elotuzumab to Lenalidomide/low-dose Dexamethasone will increase the progression free survival (PFS).

NCT ID: NCT01239732 Completed - Ovarian Cancer Clinical Trials

A Study of the Addition of Avastin (Bevacizumab) to Carboplatin and Paclitaxel Therapy in Patients With Ovarian Cancer

Start date: December 2010
Phase: Phase 3
Study type: Interventional

This open-label, non-comparative, multi-center study will assess the safety profile and efficacy of Avastin (bevacizumab) when added to carboplatin and paclitaxel therapy in patients with epithelial ovarian cancer, fallopian tube carcinoma or primary peritoneal carcinoma. Patients will receive 15 mg/kg Avastin intravenously on Day 1 of every cycle for up to 36 cycles of 3 weeks each, carboplatin (AUC 5-6 mg/ml/min) on Day 1 every 3 weeks for a maximum of 8 cycles and paclitaxel 175 mg/m2 on Day 1 every 3 weeks or 80 mg/m2 every week for a maximum of 8 cycles. The anticipated time on study drug will be 108 weeks or until disease progression or unacceptable toxicity.

NCT ID: NCT01238757 Completed - Respiratory Failure Clinical Trials

Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI)

NavPed-NI
Start date: June 2010
Phase: N/A
Study type: Interventional

The purpose of this study is - to document the prevalence and type of asynchronies incidence during non-invasive mechanical ventilation in pediatric patients breathing under pressure support. - to observe the impact of adjusting the expiratory trigger setting on asynchronies during pressure support - and compare these incidences with asynchronies measured in pediatric patient breathing under NAVA system (Neurally Adjusted Ventilatory Assist).

NCT ID: NCT01238497 Completed - Clinical trials for Severe Aortic Stenosis

SOURCE XT REGISTRY

Start date: September 2010
Phase:
Study type: Observational

This registry is to expand upon existing data sets, to identify patient characteristics and indicators related to complications and clinical benefits for patients with symptomatic severe calcific degenerative aortic stenosis that are undergoing treatment with the commercially available Edwards SAPIEN XTâ„¢ Valve, and delivery devices.

NCT ID: NCT01234714 Completed - Surgery Clinical Trials

Liver Fat Quantification by Magnetic Resonance Imaging (MRI) - Prediction of Postoperative Complications

MRsteatosis
Start date: October 2010
Phase: N/A
Study type: Observational

The purpose of this study is to objectively quantify liver fat content (LFC) by Magnetic Resonant Imaging (MRI) prior to major liver surgery, and to investigate its association with post-operative complications.