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NCT ID: NCT01731639 Completed - Pregnancy Clinical Trials

Motile Sperm Organelle Morphology Examination (MSOME) Influence on Intracytoplasmic Sperm Injection (ICSI) Outcomes in Infertile Couples

Start date: January 2013
Phase: N/A
Study type: Interventional

A new technique based on the motile sperm organelle morphology examination (MSOME) at a magnification of at least ×6000 has been developed. The MSOME assesses the nucleus, for both shape and chromatin content, which is the most important sperm organelle in influencing intracytoplasmic sperm injection (ICSI) outcomes.

NCT ID: NCT01731600 Completed - Clinical trials for Congenital Bleeding Disorder

A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients With Severe Haemophilia A

pathfinderâ„¢5
Start date: February 20, 2013
Phase: Phase 3
Study type: Interventional

This trial is conducted globally. The aim of the trial is to investigate safety, efficacy and pharmacokinetics (the exposure of the trial drug in the body) of NNC 0129-0000-1003 (N8-GP) in children with severe haemophilia A who have undergone treatment with previous factor VIII (FVIII) products.

NCT ID: NCT01730534 Completed - Clinical trials for Diabetes Mellitus, Non-Insulin-Dependent

Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events

DECLARE-TIMI58
Start date: April 25, 2013
Phase: Phase 3
Study type: Interventional

This study is being carried out to determine the effect of dapagliflozin on cardiovacular outcomes when added to current background therapy in patients with type 2 diabetes with either established cardiovacular disease or cardiovascular risk factors.

NCT ID: NCT01730352 Completed - Clinical trials for Helicobacter Pylori Infection

Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients

Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether eradication of Helicobacter pylori infection is effective in the improvement of platelet counts in children and adolescents with chronic ITP.

NCT ID: NCT01728337 Completed - Clinical trials for Sun-induced Wrinkles

Phase IV Study On Muscle Activity Of Two Commercial Preparations Of Botulinum

Start date: July 2011
Phase: Phase 4
Study type: Interventional

this study was proposed to provide more scientific and objective data on the clinical and aesthetic effects of these two toxins (Dysport and Xeomin).

NCT ID: NCT01727986 Completed - Clinical trials for Juvenile Idiopathic Arthritis

An Extension Long-Term Study of RoActemra/Actemra (Tocilizumab) in Patients With Polyarticular Juvenile Idiopathic Arthritis Who Completed The WA19977 Study

Start date: March 2013
Phase: Phase 3
Study type: Interventional

This long-term, open-label extension study will evaluate the safety of RoActemra/Actemra (tocilizumab) in patients with polyarticular-course juvenile idiopathic arthritis who completed the WA19977 core study. Patients aged 9-18 years with at least JIA ACR30 clinical response to RoActemra/Actemra in the core study will be eligible to receive RoActemra/Actemra 8 mg/kg intravenously every 4 weeks. Anticipated time on study treatment is 104 weeks.

NCT ID: NCT01727947 Completed - Pregnancy Clinical Trials

Influence of Sperm With Large Nuclear Vacuole on ICSI Outcomes

Start date: January 2013
Phase: N/A
Study type: Interventional

Current research on sperm morphology has been directed towards the dysmorphisms of the sperm head. A new technique based on the motile sperm organelle morphology examination (MSOME) allows the detection of sperm with large nuclear vacuoles (SLV). Large nuclear vacuoles are specific sperm alterations observed under high magnification, and their presence has been related to increased DNA fragmentation and denaturation.

NCT ID: NCT01727063 Completed - Clinical trials for Coronary Artery Disease

Cell Therapy in Severe Chronic Ischemic Heart Disease

MiHeart
Start date: January 2006
Phase: Phase 3
Study type: Interventional

Patients with advanced coronary artery disease usually undergo incomplete myocardial revascularization due to the extension and diffuseness of the disease, with very poor distal arterial beds unsuitable for direct revascularization. This study was designed to test the hypothesis that direct, intramyocardial injection of autologous bone marrow cells may further improve myocardial perfusion in patients undergoing incomplete bypass surgery.

NCT ID: NCT01727024 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Study Evaluating Preference, Satisfaction And Correct Use Of Inhalers In COPD Patients

INHALATOR
Start date: April 2013
Phase: Phase 4
Study type: Interventional

This study compared the correct use of and patient preference for two drug delivery systems (inhalers) in patients with COPD

NCT ID: NCT01726335 Completed - Schizophrenia Clinical Trials

Switching From Oral Antipsychotics to Long-Acting Risperidone in Participants With Schizophrenia

Start date: January 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate efficacy, safety and tolerance of long-acting risperidone when switching from oral antipsychotics in participants with schizophrenia (psychiatric disorder with symptoms of emotional instability, detachment from reality, often with delusions and hallucinations, and withdrawal into the self).