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NCT ID: NCT01456936 Completed - Smoking Cessation Clinical Trials

Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders

EAGLES
Start date: November 2011
Phase: Phase 4
Study type: Interventional

This study is being conducted to assess varenicline and bupropion as aids to smoking cessation treatment in subjects with and without an established diagnosis of major psychiatric disorder and to characterize the neuropsychiatric safety profile (pre-specified adverse events (AEs) in both of these populations).

NCT ID: NCT01456728 Completed - Clinical trials for Helicobacter Pylori Infection

Lactobacillus Reuteri ProGastria in Helicobacter Pylori-infected Adult Subjects on Proton Pump Inhibitors

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The purpose of the study is to confirm that simultaneous use of L. reuteri ProGastria and omeprazole for 28 days can eradicate H. pylori in humans in the absence of antibiotics.

NCT ID: NCT01456195 Completed - Clinical trials for Diabetes Mellitus, Type 2

Comparison of TAK-875 With Placebo in Participants With Type 2 Diabetes

Start date: November 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of TAK-875, once daily (QD), in participants with type 2 diabetes mellitus (T2DM).

NCT ID: NCT01456169 Completed - Clinical trials for Essential Hypertension

A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone

Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of the fixed dose combinations of azilsartan medoxomil plus chlorthalidone (40/12.5 and 40/25 mg), once daily, in participants with grades 2 or 3 essential hypertension who do not reach target blood pressure following treatment with 40 mg azilsartan medoxomil monotherapy after 4 weeks.

NCT ID: NCT01455896 Completed - Type 2 Diabetes Clinical Trials

A Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With ITCA 650

Start date: March 2013
Phase: Phase 3
Study type: Interventional

Phase 3 study to Evaluate cardiovascular outcomes in patients with type 2 diabetes treated with ITCA 650.

NCT ID: NCT01455402 Completed - Clinical trials for Respiratory Syncytial Virus, Chronic Obstructive Pulmonary Disease, Congestive Heart Failure

An Observational Study to Assess RSV-associated Illness in Adults With COPD and/or CHF

CD-1089
Start date: July 2010
Phase: N/A
Study type: Observational

The primary objective of this observational study is to determine the incidence of medically attended (inpatient or outpatient) acute respiratory illnesses or events leading to worsening cardiorespiratory status (ie, acute exacerbations of chronic obstructive pulmonary disease [AECOPD] or worsening CHF) associated with RSV infections in high-risk adults (ie, those with severe COPD and/or advanced CHF) across multiple consecutive RSV seasons.

NCT ID: NCT01449162 Completed - Asthma Clinical Trials

Masitinib in Treatment of Patients With Severe Persistent Asthma Treated With Oral Corticosteroids

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The study objective is to compare the efficacy and the safety of masitinib at 6 mg/kg/day versus placebo in the treatment of patients with Severe Persistent Asthma treated with oral corticosteroids.

NCT ID: NCT01448850 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Study to Evaluate the Efficacy of MEDI8968 in Chronic Obstructive Pulmonary Disease

SPRING
Start date: November 2011
Phase: Phase 2
Study type: Interventional

A Phase 2 Double-blind, Placebo-controlled Study to Evaluate the Efficacy of MEDI8968 in Chronic Obstructive Pulmonary Disease

NCT ID: NCT01445678 Completed - Clinical trials for Complicated Intra-abdominal Infection

Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Meropenem in Complicated Intraabdominal Infections

Start date: December 23, 2011
Phase: Phase 3
Study type: Interventional

This is a Phase 3, multicenter, prospective, randomized, double-blind, double dummy study of CXA-201 Intravenous (IV) infusions (1500mg q8h) and metronidazole (500mg q8h) versus meropenem (1000mg q8h)for the treatment of adults with Complicated Intraabdominal Infections (cIAI).

NCT ID: NCT01444430 Completed - Asthma Clinical Trials

A 6 Month Safety Study Comparing Symbicort With Inhaled Corticosteroid Only in Asthmatic Adults and Adolescents

Start date: December 2011
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the safety of Symbicort compared to inhaled corticosteroid alone during 6 months in adult and adolescent patients with asthma