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NCT ID: NCT00757133 Completed - Aortic Aneurysm Clinical Trials

Prevention of Incisional Hernia by Mesh Augmentation After Midline Laparotomy for Aortic Aneurysm Treatment

PRIMAAT
Start date: November 2008
Phase: N/A
Study type: Interventional

The research hypothesis for this study is to possibly reduce the incidence of incisional hernia 2 years postoperatively after midline laparotomy for treatment of aortic aneurysm from 25% to 5% by mesh augmentation during closure of the laparotomy. The study is designed as a prospective randomised multi-centre trial, randomising patients in 2 groups concerning the surgical technique of the closure of the abdominal wall.

NCT ID: NCT00756210 Completed - Obesity Clinical Trials

Lifestyle and Obesity

Start date: n/a
Phase: N/A
Study type: Interventional

The objective of this trial is to determine the effect of different lifestyle interventions such as aerobic exercise and alternative resistance training methods, combined with a hypocaloric diet, on weight, body composition and metabolic risk factors in overweight and obese adults.

NCT ID: NCT00756145 Completed - Clinical trials for Chronic Kidney Disease

The Use of Low Molecular Weight Heparin in Hemodiafiltration

Start date: September 2008
Phase: Phase 4
Study type: Interventional

Low molecular weight heparin (LMWH) is injected in the dialysis circuit at the start of the session. In the present study we compare 3 different methods of injection of LMWH: parameters of dialysis efficiency and clotting are measured. The study lasts 3 sessions for each patient.

NCT ID: NCT00755807 Completed - Multiple Sclerosis Clinical Trials

Duloxetine for Multiple Sclerosis Pain

Start date: October 2008
Phase: Phase 3
Study type: Interventional

This study is designed to primarily assess the efficacy and safety of duloxetine 60-120 mg once daily (QD) compared with placebo on the reduction of pain severity in participants with central neuropathic pain due to Multiple Sclerosis.

NCT ID: NCT00755287 Completed - Clinical trials for Diabetes Mellitus Type 2

A Study of the Safety, Tolerability and Effect on Glycemic Control of Taspoglutide Versus Insulin Glargine in Insulin Naive Type 2 Diabetic Patients Inadequately Controlled With Metformin Plus Sulphonylurea.

Start date: November 2008
Phase: Phase 3
Study type: Interventional

This 3-arm study will assess the efficacy, safety and tolerability of taspoglutide compared to insulin glargine in patients with insulin-naive type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea combination therapy. Patients will be randomized to receive taspoglutide (10 mg once weekly, or 10mg once weekly for 4 weeks followed by 20mg once weekly) or insulin glargine (starting dose 10 IU/day) in a ratio of 1:1:1 in addition to continued prestudy metformin treatment. The anticipated time on study treatment is 2+ years, and the target sample size if 500+ individuals.

NCT ID: NCT00753961 Completed - Healthy Clinical Trials

Effect Of The Consumption Of Fermented Dairy Drink On Common Infections In Shift-Workers

Start date: September 2008
Phase: N/A
Study type: Interventional

This clinical study plans to investigate the effect of the consumption of a fermented dairy drink on the occurrence of common infections. This study will be performed in a healthy adult population of shift workers.

NCT ID: NCT00753688 Completed - Clinical trials for Sarcoma, Soft Tissue

Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy

PALETTE
Start date: October 2008
Phase: Phase 3
Study type: Interventional

A randomized double blind phase III trial of Pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or following prior therapy

NCT ID: NCT00753545 Completed - Ovarian Cancer Clinical Trials

Assessment of Efficacy of AZD2281 in Platinum Sensitive Relapsed Serous Ovarian Cancer

Start date: August 28, 2008
Phase: Phase 2
Study type: Interventional

The primary purpose of this study to determine if AZD2281 is effective and well tolerated in maintaining the improvement in your cancer after previous platinum-based chemotherapy

NCT ID: NCT00753272 Completed - Influenza Clinical Trials

Trial to Evaluate the Efficacy of GSK Biologicals' Influenza Vaccine GSK2186877A in Adults 65 Year of Age and Older

Start date: September 15, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of GlaxoSmithKline Biologicals' influenza vaccine GSK2186877A in adults 65 year of age and older. The study design is divided in two surveillance phases: one passive phase along the study during the influenza season and one active surveillance phase during the influenza peak season.

NCT ID: NCT00752804 Completed - Renal Failure Clinical Trials

Uremic Toxins in the ICU: Patients After Cardiac Surgery

Start date: July 31, 2008
Phase: N/A
Study type: Interventional

Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients after cardiac surgery.The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)