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NCT ID: NCT02459197 Completed - Osteoarthritis Clinical Trials

A Proof of Concept Study to Investigate the Effect of a New Treatment in Patient With Chronic Pain

Start date: June 2015
Phase: N/A
Study type: Interventional

The purpose of this clinical trial conducted in patients suffering from chronic pain is to study the relationship between individual patients' profile and their analgesic response

NCT ID: NCT02457546 Completed - Clinical trials for Cerebrospinal Fluid Leak

The EVICEL® Neurosurgery Phase III Study

Start date: July 1, 2015
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the safety and efficacy of EVICEL® Fibrin Sealant (Human) for use as an adjunct to sutured dural repair in cranial surgery.

NCT ID: NCT02456740 Completed - Migraine Clinical Trials

Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention

STRIVE
Start date: July 17, 2015
Phase: Phase 3
Study type: Interventional

The primary objective of the study was to evaluate the effect of erenumab compared to placebo on the change from baseline in monthly migraine days.

NCT ID: NCT02454972 Completed - Clinical trials for Advanced Solid Tumors

Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid Tumors

Start date: August 25, 2015
Phase: Phase 2
Study type: Interventional

Multicenter, open-label, exploratory, phase II clinical trial to evaluate the efficacy and safety of PM01183 in previously treated patients with advanced solid tumors

NCT ID: NCT02454829 Completed - Female Infertility Clinical Trials

Follow-up of Ovarian Function in Young Women Who Underwent Ovarian Cortex Cryopreservation

Start date: March 2015
Phase: N/A
Study type: Observational

Evaluation of ovarian function by a questionnaire and by medical file analysis of women and girls who underwent ovarian cortex cryopreservation for fertility preservation between 1997 an 2013 in the investigators' institution in order to evaluate their residual ovarian function. A second part of the questionnaire concerns these women's satisfaction regarding the procedure.

NCT ID: NCT02454062 Completed - Clinical trials for Advanced Solid Tumors

A Trial of TAS-114 in Combination With S-1

Start date: March 2013
Phase: Phase 1
Study type: Interventional

A Phase I, Open-Label, International, Multicenter, Non-Randomized, Dose-Escalating Safety, Tolerance and Pharmacokinetic Study of Oral Administration of TAS-114 in Combination with S-1 in a Twice Daily Schedule for 14 Days in Patients with Advanced Solid Tumors.

NCT ID: NCT02453711 Completed - Obesity Clinical Trials

Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus

Start date: October 1, 2015
Phase: Phase 2
Study type: Interventional

This trial is conducted globally. The aim of this trial is to investigate safety and efficacy of once-daily semaglutide in obese subjects without diabetes mellitus.

NCT ID: NCT02453672 Completed - Healthy Clinical Trials

Pharmacokinetic, Safety, Tolerability, and Immunogenicity Study of SB8 in Healthy Male Subjects

Start date: April 2015
Phase: Phase 1
Study type: Interventional

Pharmacokinetics, Safety, Tolerability, and Immunogenicity of Three Formulations of Bevacizumab

NCT ID: NCT02453256 Completed - Systemic Sclerosis Clinical Trials

A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)

focuSSced
Start date: November 20, 2015
Phase: Phase 3
Study type: Interventional

This study will assess the efficacy and safety of tocilizumab compared with placebo in participants with SSc across approximately 120 planned global study sites. The study will consist of a 48-week, double-blind, placebo-controlled period followed by a 48-week open-label treatment period. Participants will be assigned, in a 1:1 ratio, to double-blind treatment with active tocilizumab or matching placebo. In the open-label period, eligible participants from either arm may receive active tocilizumab.

NCT ID: NCT02452190 Completed - Asthma Clinical Trials

Study of Reslizumab in Participants With Uncontrolled Asthma and Elevated Blood Eosinophils

Start date: September 28, 2015
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to determine the effect of reslizumab (110 mg) administered subcutaneously every 4 weeks on clinical asthma exacerbations in adults and adolescents with asthma and elevated blood eosinophils who are inadequately controlled on standard-of-care asthma therapy.