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NCT ID: NCT04333134 Completed - Healthy Volunteers Clinical Trials

A Trial of SHR3162 in Healthy Caucasian Volunteers

Start date: April 17, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and PK characteristics of a single oral dose of fluzoparib in healthy Caucasian and Chinese subjects

NCT ID: NCT04328766 Completed - Clinical trials for Drug-drug Interaction

Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers

Start date: September 6, 2020
Phase: Phase 1
Study type: Interventional

An open-label, multiple-dose clinical trial to evaluate the safety/tolerability and pharmacokinetic interaction between DWP14012 and DWC202005 in healthy volunteers

NCT ID: NCT04327206 Completed - COVID-19 Clinical Trials

BCG Vaccination to Protect Healthcare Workers Against COVID-19

BRACE
Start date: March 30, 2020
Phase: Phase 3
Study type: Interventional

Phase III, two-group multicentre, randomised controlled trial in up to 10 078 healthcare workers to determine if BCG vaccination reduces the incidence and severity of COVID-19 during the 2020 pandemic.

NCT ID: NCT04327024 Completed - Clinical trials for Heart Failure With Preserved Ejection Fraction (HFpEF)

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

AMETHYST
Start date: May 19, 2020
Phase: Phase 2
Study type: Interventional

International, Multicenter, Double-Blind, Placebo and Active Control Efficacy and Safety Study to Evaluate Verinurad combined with Allopurinol in Heart Failure with Preserved Ejection Fraction

NCT ID: NCT04326127 Completed - Sleep Apnea Clinical Trials

Evaluation of Compumedics "Somfit" Device

Start date: November 6, 2019
Phase:
Study type: Observational

To study whether Somfit is substantially equivalent to an existing approved device (i.e. Compumedic's Grael System) to assist in elucidating sleep disorders.

NCT ID: NCT04324814 Completed - Clinical trials for Advanced Solid Tumor

A Trial of SHR-1701 in Subjects With Advanced Solid Tumors

Start date: March 31, 2020
Phase: Phase 1
Study type: Interventional

This is a dose-escalation and dose-expansion Phase 1 trial to evaluate the safety and tolerability of SHR-1701 in subjects with advanced solid tumors.

NCT ID: NCT04323306 Completed - Malaria Clinical Trials

A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.

Start date: August 12, 2020
Phase: Phase 1
Study type: Interventional

Phase 1, single -centre study in 2 parts. The study designs for each part are well established for first-in-human studies and are appropriate to assess safety, tolerability and preliminary pharmacokinetics.

NCT ID: NCT04322708 Completed - Clinical trials for Eosinophilic Esophagitis

A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis

KRYPTOS
Start date: July 6, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This is a Phase 2/3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult and adolescent patients with active eosinophilic esophagitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to receive 6 doses of open-label lirentelimab (AK002) through the OLE Period of the study.

NCT ID: NCT04321980 Completed - Healthy Clinical Trials

A Clinical Study to Measure the Effect of OP-101 After Being Administered Subcutaneous in Healthy Volunteers

Start date: March 19, 2020
Phase: Phase 1
Study type: Interventional

A clinical study to measure the Safety, Tolerability, and Pharmacokinetics of OP-101 After Subcutaneous Administration in Healthy Volunteers

NCT ID: NCT04318704 Completed - Clinical trials for Idiopathic Pulmonary Fibrosis

Efficacy, Safety and Tolerability of NP-120 on Idiopathic Pulmonary Fibrosis and Its Associated Cough

Start date: July 29, 2020
Phase: Phase 2
Study type: Interventional

NP-120 (Ifenprodil) has been shown to mediate anti-inflammatory responses and reduce pulmonary fibrosis in a murine model of Idiopathic Pulmonary Fibrosis (IPF). In addition, NP-120 significantly reduced both cough frequency and onset in a guinea pig tussive model. The purpose of this proof-of-concept trial is to determine the efficacy of NP-120 in the treatment of IPF and its associated cough.