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NCT ID: NCT00604825 Completed - Clinical trials for Menopausal and Female Climacteric States

Treatment Of Hot Flashes/Flushes In Postmenopausal Women (WARM Study)

Start date: July 17, 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether GSK232802 is safe and effective in reducing the frequency and severity of hot flashes associated with menopause.

NCT ID: NCT00604214 Completed - Sepsis Clinical Trials

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The purpose of this placebo-controlled study is to determine if drotrecogin alfa (activated) treatment provides significant mortality reduction improvement in patients with septic shock compared with placebo treatment in patients receiving the current standard of care for septic shock. This study will also assess the effectiveness of drotrecogin alfa (activated) in reducing 28-day mortality in patients with septic shock and concomitant severe protein C deficiency.

NCT ID: NCT00604006 Completed - Heart Failure Clinical Trials

SCREEN-HFI (SCReening Evaluation of the Evolution of New Heart Failure Intervention Study)

Start date: September 2008
Phase: Phase 3
Study type: Interventional

Individuals who were a part of the investigators Screen-HF study (NCT00400257) whose BNP level are in the top quintile will be offered participation in this study. Participants will be randomised to receive either spironolactone or placebo for three years. Participants will then be monitored for indications of heart failure. It is anticipated that the medication will reduce the development of heart failure in this group.

NCT ID: NCT00603746 Completed - Asthma Clinical Trials

A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Moderate-Dose ICS Therapy.

Start date: December 2007
Phase: Phase 2
Study type: Interventional

This study is designed to determine if the investigational drug is effective and safe in individuals with asthma.

NCT ID: NCT00602004 Completed - Renal Failure Clinical Trials

Attenuation of Cardiac Effects of Arteriovenous Fistula Creation With Losartan

Start date: October 2006
Phase: N/A
Study type: Interventional

The primary objective is to determine if the use of losartan, an angiotensin II receptor blocker, can attenuate left ventricular hypertrophy, independent of its antihypertensive effects, in patients with near end stage chronic kidney disease (CKD) who have an arteriovenous fistula created. Secondary outcomes include the impact of the medication on BNP and hyperkalaemia

NCT ID: NCT00600990 Completed - Clinical trials for Postoperative Nausea and Vomiting

Study Of An NK-1 Anti-Emetic Medication For The Prevention Of Post-Operative Nausea And Vomiting In Female Patients

Start date: December 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of this medication in preventing nausea and vomiting in female patients at risk for post-operative nausea and vomiting (PONV).

NCT ID: NCT00599911 Completed - Clinical trials for Major Depressive Disorder

Dose-finding Study With Lu AA24530 in Major Depressive Disorder

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to assess the efficacy in treating patients with Major Depressive Disorder of one or more doses of Lu AA24530 relative to placebo

NCT ID: NCT00599274 Completed - Multiple Sclerosis Clinical Trials

Study to Determine if Avonex and Rebif Work Comparably Well in Subjects With Relapsing Multiple Sclerosis

PROOF
Start date: August 2002
Phase: N/A
Study type: Observational

The purpose of this study is to find out if weekly Avonex works as well as three times a week Rebif in subjects with relapsing multiple sclerosis.

NCT ID: NCT00599196 Completed - Clinical trials for Early Stage Parkinson's Disease

An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Early-Stage Parkinson's Disease

Start date: August 2002
Phase: Phase 3
Study type: Interventional

The objective of this open-label extension is to assess the safety and tolerability of long-term treatment of the rotigotine patch in subjects with early-stage idiopathic Parkinson's disease

NCT ID: NCT00595049 Completed - Clinical trials for Hypertension, Pulmonary

Pulmonary Artery Remodelling With Bosentan

Start date: May 2006
Phase: Phase 4
Study type: Interventional

The main purpose of this study is to investigate whether bosentan (Tracleer®) affects the wall thickness of the pulmonary arteries in patients with idiopathic pulmonary arterial hypertension (iPAH) and PAH related to systemic sclerosis (PAH-SSc). The second purpose is to investigate if bosentan affects the enlargement of small vessels in the lungs in response to natural chemicals in patients with iPAH and PAH-SSc.