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NCT ID: NCT01068912 Completed - Influenza Clinical Trials

Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza

Start date: February 2010
Phase: Phase 2
Study type: Interventional

This is a Phase 2, randomized, double-blind, placebo-controlled multicenter study evaluating the efficacy and safety of two doses of favipiravir in adult patients with uncomplicated influenza.

NCT ID: NCT01068860 Completed - Clinical trials for Type 2 Diabetes Mellitus

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Start date: February 2010
Phase: Phase 2
Study type: Interventional

This was a 10-week, placebo-controlled, randomized study to investigate the effect of injectable IL-1B antagonist, Canakinumab , in participants with impaired glucose tolerance or Type 2 Diabetes Mellitus (T2DM) already treated on different background diabetes therapies.

NCT ID: NCT01068509 Completed - Clinical trials for Epithelial Ovarian Cancer

Ovarian Cancer Vaccine for Patients in Remission

Start date: June 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of an investigational therapeutic agent (Cvac)in ovarian cancer patients in first or second remission and to determine its ability to prevent cancer from returning.

NCT ID: NCT01066936 Completed - Osteoarthritis, Hip Clinical Trials

Mini Stem DEXA (Dual Energy X-ray Absorptiometry)

MISDexa
Start date: September 14, 2009
Phase:
Study type: Observational

The objective of this study is to evaluate the bone ingrowth after implantation of the study device. This study will also document any device-related surgical complications or adverse radiographic observations. Improvement in pain, function, and health economic data will be compared with improvements documented with other joint systems.

NCT ID: NCT01065935 Completed - Clinical trials for Respiratory Syncytial Virus Infections

Phase 2b Study of ALN-RSV01 in Lung Transplant Patients Infected With Respiratory Syncytial Virus (RSV)

Start date: February 2010
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of ALN-RSV01 plus standard of care in RSV infected lung transplant patients

NCT ID: NCT01065090 Completed - Exercise Clinical Trials

A Single-blinded, Controlled, Multi-centre Study of Effects of Exercise in Participants With Multiple Sclerosis

ACTIMS
Start date: June 2010
Phase: N/A
Study type: Observational

The primary objective of the investigation is to determine whether the addition of exercise (resistance training or modified physiotherapy) improves functional capacity in Multiple Sclerosis (MS) participants undergoing Disease Modifying Therapy (DMT) treatment. We hypothesize that the Progressive Resistance Training (PRT) will improve functional capacity without increasing the risk of relapses in participants undergoing standard DMT treatment. The secondary objectives are to determine whether exercise (resistance training or physiotherapy) improves fatigue, mood and Quality of Life (QoL) in MS participants undergoing DMT treatment. Also as a secondary objective, the study aims at determining whether exercise (resistance training or modified physiotherapy) has an impact on Expanded Disability Status Scale (EDSS), time to first relapse, number of relapse free participants, and immunological factors. We hypothesize that the exercise (resistance training) will improve fatigue, mood and QoL and that an impact on immunological factors will be seen in participants even though they are undergoing standard DMT treatment.

NCT ID: NCT01064791 Completed - Clinical trials for Renal Transplantation

Efficacy, Safety, Tolerability, and Pharmacokinetics of Sotrastaurin Combined With Tacrolimus vs. a Mycophenolic Acid-tacrolimus Regimen in Renal Transplant Patients

Start date: December 2009
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of different doses of sotrastaurin when combined with tacrolimus for the prevention of acute rejection after de novo renal transplantation.

NCT ID: NCT01064414 Completed - Clinical trials for Diabetes Mellitus, Type 2

An Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment

Start date: June 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who have reduced kidney function.

NCT ID: NCT01064401 Completed - Clinical trials for Relapsing-Remitting Multiple Sclerosis

Efficacy and Safety of BIIB019 (Daclizumab High Yield Process) Versus Interferon β 1a in Participants With Relapsing-Remitting Multiple Sclerosis

(DECIDE)
Start date: May 2010
Phase: Phase 3
Study type: Interventional

The primary study objective is to test the superiority of Daclizumab High Yield Process (DAC HYP) compared to interferon β 1a (IFN β-1a) in preventing multiple sclerosis (MS) relapse in participants with relapsing remitting multiple sclerosis. The secondary study objectives are to test the superiority of DAC HYP compared to IFN β-1a in slowing functional decline and disability progression and maintaining quality of life in this participant population.

NCT ID: NCT01063881 Completed - Clinical trials for Sexual Dysfunction, Physiological

The Asia-Pacific Flexible Dose Study of Dapoxetine and Patient Satisfaction in Premature Ejaculation Therapy

Start date: May 2010
Phase: Phase 3
Study type: Interventional

The purpose of the study is to measure the efficacy of flexible dosing of dapoxetine in a setting similar to routine clinical practice.