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NCT ID: NCT03883620 Completed - Dengue Clinical Trials

Safety Study of Dengushield in Healthy Adults

Start date: March 22, 2019
Phase: Phase 1
Study type: Interventional

This Phase 1 study to evaluate the safety of a single dose of Dengushield (dengue monoclonal antibody) in healthy adults.

NCT ID: NCT03882671 Enrolling by invitation - Epilepsy Clinical Trials

Development of a Minimally Invasive Seizure Gauge

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The researchers are trying to assess changes in physiological signals before and during seizures.

NCT ID: NCT03880474 Terminated - Influenza Clinical Trials

Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults

Start date: March 18, 2019
Phase: Phase 2
Study type: Interventional

A Phase 2b Study to Determine the Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults aged 18 years and over. To assess the effect of MVA-NP+M1 on the reduction of laboratory confirmed influenza when given as an adjunct to licensed quadrivalent influenza vaccine (QIV) in adults

NCT ID: NCT03880292 Completed - Spinal Deformity Clinical Trials

Spinal Deformity Intraoperative Monitoring.

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

A multicenter, international prospectively collected patient cohort undergoing high-risk spinal cord level surgery or spinal osteotomy procedures will be enrolled to establish the incidence of intraoperative alerts in high-risk spinal cord cases, and explore factors associated with mitigating injury. Baseline, intraoperative, and postoperative characteristics, including demographics, radiological features, lower extremity motor score (LEMS), procedure, anesthetic agents used, and baseline blood pressure will be recorded for either adult patients or pediatric patients.

NCT ID: NCT03879759 Recruiting - Alcohol Dependence Clinical Trials

The Efficacy and Neurobehavioural Mechanism of N-acetyl Cysteine (NAC) for Alcohol Dependence

Start date: August 22, 2018
Phase: Phase 2
Study type: Interventional

The study will explore the efficacy and tolerability of a regimen of NAC (2400 mg) versus placebo for the treatment of alcohol dependence.

NCT ID: NCT03876457 Completed - Clinical trials for Acute Ischemic Stroke

SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke

SELECT2
Start date: October 11, 2019
Phase: N/A
Study type: Interventional

SELECT 2 evaluates the efficacy and safety of endovascular thrombectomy compared to medical management alone in acute ischemic stroke patients due to a large vessel occlusion in the distal ICA and MCA M1 who have large core on either CT (ASPECTS: 3-5) or advanced perfusion imaging ([rCBF<30%] on CTP or [ADC<620] on MRI: ≥50cc) or both and are treated within 0-24 hours from last known well.

NCT ID: NCT03876301 Completed - Hemophilia A Clinical Trials

Lead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Participants

Start date: January 21, 2019
Phase:
Study type: Observational

The aim of this prospective, observational study is to establish a dataset on the frequency of bleeding events, as well as other characteristics of bleeding events and FVIII infusions, in patients with clinically severe hemophilia A receiving prophylactic FVIII replacement therapy as standard of care. The data collected from this study may assist in providing baseline information for comparison to the Spark's investigational hemophilia A gene therapy in future Phase 3 studies.

NCT ID: NCT03876054 Recruiting - Chronic Pain Clinical Trials

Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator

REALITY
Start date: March 13, 2019
Phase:
Study type: Observational

The REALITY study is a prospective, post-market, non-randomized, multi-center, single-arm, open-label study intended to collect short- and long-term safety and effectiveness data on various populations implanted with Abbott's neurostimulation systems.

NCT ID: NCT03875534 Completed - Achondroplasia Clinical Trials

A Multi-center, Longitudinal, Observational Study of Children With Achondroplasia

Start date: June 19, 2019
Phase:
Study type: Observational

This is a long-term, multi-center, longitudinal, observational study in children with achondroplasia (ACH). The aim is to study height velocity and comorbidities in children with ACH. This is a natural history study and no study medication will be administered.

NCT ID: NCT03875469 Completed - Computed Tomography Clinical Trials

Study to Test the Usability of a New Injector to Administer Contrast Media Into Humans for Diagnostic Purposes

PERCENT
Start date: June 21, 2019
Phase: N/A
Study type: Interventional

This study investigates if a new medical device, which injects contrast media and flushing solution into humans to increase the visibility of images taken of the human body for diagnostic purposes, is easier to handle, quicker and cheaper than an older injector.