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NCT ID: NCT02534467 Completed - Dermatitis, Atopic Clinical Trials

Does Treatment With Montelukast Improve Symptoms of Atopic Dermatitis in Children?

Start date: July 9, 2015
Phase: Phase 4
Study type: Interventional

An open-label (outcome assessor blinded) prospective crossover cohort study of children 6-16 years assessing effects of Montelukast on moderate to severe atopic dermatitis.

NCT ID: NCT02534350 Completed - Clinical trials for Respiratory Syncytial Virus (RSV)

Presatovir in Lung Transplant (LT) Recipients With Respiratory Syncytial Virus (RSV) Infection

Start date: December 31, 2015
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the effect of presatovir on nasal respiratory syncytial virus (RSV) viral load in RSV-positive lung transplant (LT) recipients with acute respiratory symptoms.

NCT ID: NCT02532283 Completed - Influenza A Virus Clinical Trials

A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection

Start date: December 11, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the Pharmacokinetic parameters of JNJ-63623872 in combination with oseltamivir in elderly participants (aged 65 to <= 85 years) compared to adults (aged 18 to <= 64 years) with influenza A infection.

NCT ID: NCT02531035 Completed - Clinical trials for Type 1 Diabetes Mellitus (T1DM)

A Phase 3 Study to Evaluate the Safety of Sotagliflozin in Patients With Type 1 Diabetes Who Have Inadequate Glycemic Control With Insulin Therapy Alone

inTandem3
Start date: September 2015
Phase: Phase 3
Study type: Interventional

This Phase 3 study was designed to demonstrate the net benefit of sotagliflozin versus placebo in patients with Type 1 Diabetes (T1D).

NCT ID: NCT02528799 Completed - Celiac Disease Clinical Trials

Safety and Tolerability of Nexvax2 in Subjects With Celiac Disease

Start date: August 2015
Phase: Phase 1
Study type: Interventional

A randomized, double-blind, placebo-controlled, dose titration trial, stratified by Human Leukocyte Antigen (HLA)-DQ2.5 genotype in subjects with celiac disease.

NCT ID: NCT02528188 Completed - Chronic Pain Clinical Trials

Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee

Start date: July 21, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the long-term joint safety and efficacy (pain relief) of the investigational study drug, tanezumab compared to non-steroidal anti inflammatory drugs (NSAIDs) in subjects with osteoarthritis of the hips or knees.

NCT ID: NCT02527200 Completed - Obesity Clinical Trials

Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome

Start date: November 9, 2015
Phase: Phase 3
Study type: Interventional

This trial is conducted globally. The aim of this trial is to investigate the effect of liraglutide for weight management in paediatric subjects with Prader-Willi Syndrome.

NCT ID: NCT02526420 Completed - Clinical trials for Adult Growth Hormone Deficiency

Versartis International Trial in Adults With Long-Acting Growth Hormone

VITAL
Start date: July 2015
Phase: Phase 2
Study type: Interventional

A Phase 2, open-label dose-finding safety study of individualized monthly VRS-317 dosing for five months in adults with GHD.

NCT ID: NCT02525939 Completed - Clinical trials for Acute Coronary Syndrome

Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS

dal-GenE
Start date: April 2016
Phase: Phase 3
Study type: Interventional

A placebo-controlled, randomized, double-blind, parallel group, phase III multicenter study in subjects recently hospitalized for ACS and with the appropriate genetic profile. Subjects will provide informed consent before any study-specific procedures are performed. Subject enrollment may begin in the hospital and will continue following release from the hospital. Screening procedures may be performed at the time of the index ACS event or anytime thereafter, with the condition that randomization must occur within the mandated window (4-12 weeks after the index event). Subjects will be assessed based on their medical history. Those who are likely to qualify will undergo Genotype Assay testing to evaluate genetic determination for the presence of AA genotype.

NCT ID: NCT02525198 Completed - Clinical trials for Mild Cognitive Impairment

The Cognitive Ageing Nutrition and Neurogenesis (CANN) Trial

CANN
Start date: August 1, 2015
Phase: N/A
Study type: Interventional

There is a dearth of research which takes a multi-compound approach to dietary interventions, in humans, aimed at improving outcome measures of cognition. Animal research in particular points towards fatty acids and flavonoids having a potentiating effect on each other, and possibly even being synergistic. Thus, study products will be administered in the present trial comprising both of these compounds, with a view to investigating their potential effects on cognition in older adults with mild cognitive impairment (MCI) or subjective memory impairment (SMI).