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Celiac Disease clinical trials

View clinical trials related to Celiac Disease.

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NCT ID: NCT03678935 Not yet recruiting - Clinical trials for Irritable Bowel Syndrome

Effect of FODMAP Restriction on Persistent GI-symptoms in Coeliac Patients

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

The first aim of the study is to investigate the prevalence of persistent gastrointestinal symptoms and compliance with gluten-free diet and the intake of FODMAP in adult celiac patients. A web-based survey wil be performed and thereafter a randomized controlled trial to test the effect of a FODMAP reduction in patients with celiac disease with irritable bowel-like symptoms.

NCT ID: NCT03663309 Not yet recruiting - Clinical trials for Celiac Disease in Children

Assessment of Adherence to Gluten Free Diet in Children and Adolescents by Detection of Gluten in Faecal Samples.

Start date: September 2018
Phase:
Study type: Observational

To assess the adherence to gluten free diet by measuring faecal and urinary gluten immunogenic peptides (GIP). This will provide an objective measure for adherence.

NCT ID: NCT03644602 Completed - Clinical trials for Irritable Bowel Syndrome

Low FODMAPs Diet in Gastrointestinal Disorders

FODMAPs
Start date: July 2016
Phase: N/A
Study type: Interventional

Recent studies have shown that FODMAPs (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) free diet is efficient in subjects with Irritable Bowel Syndrome (IBS). Patients with Inflammatory Bowel Diseases (IBD) and celiac disease (CD) can experience functional gastrointestinal symptoms not related to inflammation, but data about the use of low FODMAPs diet in these settings are still scarce. The aim of the present study was to evaluate the usefulness of a low FODMAPs diet in patients with IBS, non-active IBD and CD on strict gluten-free diet (GFD). A low FODMAPs diet could be a valid option to contrast abdominal symptoms in patients with IBS, non-active IBD and CD on GFD, thus improving the quality of life and the social relations.

NCT ID: NCT03644069 Recruiting - Celiac Disease Clinical Trials

A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD)

Start date: August 6, 2018
Phase: Phase 2
Study type: Interventional

A randomized, double-blind, placebo-controlled clinical study in human leukocyte antigen (HLA)-DQ 2.5+ adults with celiac disease (CeD).

NCT ID: NCT03585478 Not yet recruiting - Celiac Disease Clinical Trials

Latiglutenase as a Treatment for Celiac Disease

Start date: July 2018
Phase: Phase 2
Study type: Interventional

Single Center, Randomized, Double-Blind, Placebo Controlled, Gluten Challenge Trial in Patients with Well-Controlled Celiac Disease

NCT ID: NCT03569007 Not yet recruiting - Celiac Disease Clinical Trials

Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Treatment of Celiac Disease

Start date: October 2018
Phase: Phase 3
Study type: Interventional

To assess the efficacy and safety of larazotide acetate versus placebo for the treatment of persistent abdominal symptoms in adult celiac disease patients.

NCT ID: NCT03562221 Not yet recruiting - Clinical trials for Celiac Disease in Children

Prevention of Celiac Disease in Skåne

PreCiSe
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

This study aims to investigate the impact on being on a gluten free diet the first three years of life compared to a daily intake of a probiotic supplementation or placebo on the risk of developing celiac disease autoimmunity or celiac disease in genetically susceptible children. Study participants will be randomly allocated to one of the three study groups before the age of 4 months and will remain in that group with the corresponding intervention during the three first years of life. Regular visits to a study nurse and contact with study dietician will be scheduled. The dietician will support the families in keeping the correct diet intended for each study group.

NCT ID: NCT03543540 Completed - Celiac Disease Clinical Trials

Bioequivalence Study of Nexvax2 in Subjects With Celiac Disease

Start date: May 1, 2018
Phase: Phase 1
Study type: Interventional

A randomized, double-blind, placebo-controlled clinical study in non-homozygous human leukocyte antigen (HLA)-DQ.2.5+ adults with celiac disease (CeD).

NCT ID: NCT03521180 Recruiting - Celiac Disease Clinical Trials

A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease

Start date: May 11, 2018
Phase:
Study type: Observational

This is a model development, open label, no therapeutic treatment, three sequential group, short term-gluten challenge study in subjects with celiac disease. Immune responses are evaluated following gluten challenge. Approximately fifteen subjects with celiac disease will be enrolled in up to three sequential groups (5 subjects per group).

NCT ID: NCT03520244 Completed - Celiac Disease Clinical Trials

A 12-week Exercise Program for Adults With Celiac Disease

MOVE-C
Start date: November 15, 2016
Phase: N/A
Study type: Interventional

Engagement in regular physical activity (PA) is associated with a range of physical and psychological benefits among chronic disease populations. Celiac disease is a chronic autoimmune condition that requires strict adherence to a gluten-free diet (GFD) for the best medical outcomes, as well as to prevent detrimental health outcomes including bloating, diarrhea, constipation, and increased risk of intestinal cancers and osteoporosis. Despite following a GFD, individuals with celiac disease often report dissatisfaction with the diet, are less likely to engage in social activities, can have an imbalance in gut bacteria and up to 30% still report negative symptoms (e.g., gastro-intestinal upset). Furthermore, preliminary research revealed that rates of PA among those with celiac disease are dismal, with the majority of participants failing to engage in regular PA. The purpose of this pilot research project is to examine the effects of a 12-week structured exercise program on inactive adults with celiac disease. It is anticipated that compared to those in a wait-list control condition, participants who engage in the 12-week exercise program will report greater improvements in quality of life and experience improved balance of gut bacteria. The findings from this project may reveal an additional strategy to optimize health while living with celiac disease. In addition, results from this study will provide essential pilot data that will inform a grant application for a larger clinical trial to further investigate the role of exercise in the promotion of health and well-being among those with celiac disease.