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NCT ID: NCT03886857 Completed - Clinical trials for Spinal Cord Injuries

Segmental Mechanisms of Transcutaneous Spinal Cord Stimulation for Spasticity Control

SCS_CorE_AT
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The aim of the pilot study is to gain first insights into the interaction of transcutaneous spinal cord stimulation with the altered activity of intraspinal circuits associated with spinal spasticity. The main goal is to evaluate the validity of the chosen measures and to generate a data base for statistical planning of a subsequent clinical study.

NCT ID: NCT03886844 Completed - Weight Gain Clinical Trials

Growth and Weight Gain in ELBW Infants Fed an Exclusively Human Milk Based Diet With Prolacta®

Start date: December 2015
Phase:
Study type: Observational

Preterm infants are susceptible to postnatal growth restriction. Breast milk is the recommended source of nutrition for preterm infants. As preterm infants have enhanced nutritional requirements, multicomponent fortifiers are added to breast milk in order to establish adequate growth. Due to the various benefits of human milk feds to preterm infants, a human milk fortifier based on donor milk (Prolact+6 H2MF® Prolacta, City of Industry, California) has been developed. With this study, the investigators want to evaluate the effect of human milk fortification on weight gain in extremely low birth weight infants (ELBW, <1000g birth weight) in comparison to bovine fortification.

NCT ID: NCT03882970 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

SURPASS-3
Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effect of the study drug tirzepatide to insulin degludec on blood sugar levels in participants with type 2 diabetes. The study will last about 67 weeks and may include up to 22 visits.

NCT ID: NCT03882021 Completed - Clinical trials for Paroxysmal Atrial Fibrillation

High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Single Ablation Procedure Using a PVI-Only Strategy

WAVE-MAP AF
Start date: August 26, 2019
Phase: N/A
Study type: Interventional

The aim is to use the GRID to characterize the atrial substrate and develop a model for predicting recurrence rates after a single procedure using a PVI only approach and a contact catheter.

NCT ID: NCT03876639 Completed - Skin Physiology Clinical Trials

Topical Application of Highly Concentrated Water-in-oil Emulsions

Start date: January 16, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to I. determine the effect of repetitive application of newly developed silicone based formulations (placebo water-in-oil emulsions) on transepidermal water loss and other physiological skin parameters and II. investigate the skin penetration of the model drug fluorescein sodium in tape stripping studies to determine the in vivo penetration profile from the water-in-oil emulsions.

NCT ID: NCT03876509 Completed - Clinical trials for Pulmonary Hypertension

Non-invasive Diagnosis of Pulmonary Hypertension by Impedance Cardiography

Start date: July 4, 2018
Phase:
Study type: Observational

The goal of the study is to prospectively evaluate Impedance Cardiography as a tool to detect pulmonary hypertension. According to our hypothesis Impedance Cardiography is a valuable method to differentiate patients without pulmonary hypertension from patients with pulmonary hypertension. The main objective is to determine the sensitivity and specificity in comparison to the gold standard right heart catheterization.

NCT ID: NCT03875534 Completed - Achondroplasia Clinical Trials

A Multi-center, Longitudinal, Observational Study of Children With Achondroplasia

Start date: June 19, 2019
Phase:
Study type: Observational

This is a long-term, multi-center, longitudinal, observational study in children with achondroplasia (ACH). The aim is to study height velocity and comorbidities in children with ACH. This is a natural history study and no study medication will be administered.

NCT ID: NCT03873974 Completed - Lyme Borreliosis Clinical Trials

Performance Evaluation of the DualDur In Vitro Diagnostic System in the Diagnosis of Lyme Borreliosis

Start date: July 2, 2019
Phase:
Study type: Observational

The clinical data from the clinical trial will be used to assess the performance, sensitivity and specificity of the experimental DualDur In Vitro Diagnostic System.

NCT ID: NCT03873493 Completed - Cancer Clinical Trials

A Study Evaluating the Efficacy of Venetoclax Plus Ibrutinib in Participants With T-cell Prolymphocytic Leukemia

Start date: January 14, 2020
Phase: Phase 2
Study type: Interventional

The main objective of this study is to evaluate the efficacy of the combination of venetoclax plus ibrutinib for treating adults with T-cell prolymphocytic leukemia (T-PLL).

NCT ID: NCT03873181 Completed - Hemostasis Clinical Trials

Post-Market Evaluation of HEMOBLASTâ„¢ Bellows in Laparoscopic Abdominal, Gynecological, and Urological Surgery

NOBLE-Laparo
Start date: May 16, 2019
Phase:
Study type: Observational

A prospective, multi-center, multi-national single arm study to evaluate the performance and safety of HEMOBLASTâ„¢ Bellows in laparoscopic abdominal, gynecological, and urological surgery.