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NCT ID: NCT00606723 Completed - Clinical trials for Acute Myeloid Leukemia (AML)

Allogenic Stem Cell Transplantation for Children, Adolescents and Young Adults With Relapsed or Refractory AML

Start date: April 2010
Phase: Phase 3
Study type: Interventional

1. To evaluate whether stem cell transplantation from a matched sibling donor is equivalent to a matched unrelated donor in in a second complete remission of acute myeloid leukemia (AML). 2. To evaluate whether stem cell transplantation (SCT) after chemotherapy (FLAMSA-schema) increases survival compared to a threshold derived from historical data 3. To evaluate whether SCT from haploidentical donors for children having no matched donor will result in better survival with acceptable toxicity.

NCT ID: NCT00605280 Completed - Clinical trials for Macular Edema Associated With Diabetes Mellitus

A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.

Start date: September 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the study is to test whether Macugen injected into the eye improves vision in more patients than the currently existing standard of care laser therapy. The safety of Macugen compared to standard of care laser will also be evaluated.

NCT ID: NCT00605020 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Insulin Detemir in Combination With Insulin Aspart and Biphasic Insulin Aspart 30 in Type 2 Diabetes

PreFER
Start date: December 2, 2003
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. The aim of this trial is to investigate the efficacy and safety of an intensified treatment regimen with preprandial insulin aspart and insulin detemir once or twice daily to a more convenient regimen with biphasic insulin aspart 30 twice daily on blood glucose control in subjects with type 2 diabetes.

NCT ID: NCT00601523 Completed - Parkinson Disease Clinical Trials

Long-term Safety Study of Open-label Pramipexole Extended Release (ER) in Patients With Early Parkinson´s Disease (PD).

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The general aim of this study is to obtain long-term safety and tolerability data on pramipexole ER, in daily doses from 0.375mg to 4.5mg once daily (q.d), in patients who have previously completed a pramipexole double-blind study in early PD (248.524(NCT00479401) or 248.636(NCT00558025) trial).

NCT ID: NCT00601367 Completed - Clinical trials for Sexual Dysfunctions, Psychological

Flibanserin Evaluation Over 28 Additional Weeks in Hypoactive Sexual Desire Disorder

Start date: January 2008
Phase: Phase 3
Study type: Interventional

Safety profile of flibanserin over 28 additional weeks Distribution of preferred dose regimens

NCT ID: NCT00600431 Completed - Nevus, Pigmented Clinical Trials

Melanocytic Nevi in Children Under Chemotherapy

Start date: February 2006
Phase: N/A
Study type: Observational

Changes in nevus count in 16 children (8m, 8f) aged between 2 and 17 years (median:8 years) suffering from different malignancies were examined every three months during a one-year period after starting chemotherapy. An age and sex matched control group underwent the same skin examinations.At the start of our study, the range of number of nevi in the chemotherapy group was 0-133, in the control group 2-199.

NCT ID: NCT00600340 Completed - Clinical trials for Metastatic Breast Cancer

2-arm Trial of Paclitaxel Plus Bevacizumab vs. Capecitabine Plus Bevacizumab

TURANDOT
Start date: April 2008
Phase: Phase 3
Study type: Interventional

First-line treatment of patients with locally recurrent or metastatic, HER2-negative breast cancer who have not received prior chemotherapy for locally recurrent or metastatic disease.

NCT ID: NCT00599911 Completed - Clinical trials for Major Depressive Disorder

Dose-finding Study With Lu AA24530 in Major Depressive Disorder

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to assess the efficacy in treating patients with Major Depressive Disorder of one or more doses of Lu AA24530 relative to placebo

NCT ID: NCT00599274 Completed - Multiple Sclerosis Clinical Trials

Study to Determine if Avonex and Rebif Work Comparably Well in Subjects With Relapsing Multiple Sclerosis

PROOF
Start date: August 2002
Phase: N/A
Study type: Observational

The purpose of this study is to find out if weekly Avonex works as well as three times a week Rebif in subjects with relapsing multiple sclerosis.

NCT ID: NCT00599196 Completed - Clinical trials for Early Stage Parkinson's Disease

An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Early-Stage Parkinson's Disease

Start date: August 2002
Phase: Phase 3
Study type: Interventional

The objective of this open-label extension is to assess the safety and tolerability of long-term treatment of the rotigotine patch in subjects with early-stage idiopathic Parkinson's disease