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NCT ID: NCT01003327 Completed - Surgery Clinical Trials

Comparison of the I-gel Laryngeal Mask and the Classic Laryngeal Mask in Patients With a BMI>25

Start date: October 2009
Phase: Phase 4
Study type: Interventional

The intention of this study is to compare the performance of the single-use I-gel laryngeal mask with the classic laryngeal mask in 50 patients with a BMI>25 during elective surgery. Primary outcome is the leak pressure. Secondary outcomes include ease and duration of insertion.

NCT ID: NCT01002768 Completed - Diabetes Clinical Trials

Comparison of Hypoglycaemic Response Between NN1250 and Insulin Glargine in Type 1 Diabetics

Start date: October 2009
Phase: Phase 1
Study type: Interventional

This trial iss conducted in Europe. The aim of this clinical trial is to evaluate the hypoglycaemic response (the response to low blood sugar) to NN1250 (insulin degludec) in subjects with type 1 diabetes. The trial is designed as a two-period, crossover trial where the trial participant is randomised to one of two treatment periods.

NCT ID: NCT00999024 Completed - Retinal Veins Clinical Trials

Reflectometric Measurement of Retinal Oxygen Saturation in Patients With Chronic Obstructive Pulmonary Disease (COPD) Grade IV and Healthy Subjects

Start date: November 2009
Phase: N/A
Study type: Observational

An adequate oxygenation and retinal perfusion is essential for the function of the inner retina. There is a wide range of autoregulation mechanisms to ensure a sufficient ocular blood and oxygen supply during changes in systemic blood pressure or intraocular pressure (IOP). Nonetheless, various retinopathies such as diabetic retinopathy, which is the leading cause of blindness in people aged 20-65 in the western world, are highly associated with hypoxia (Pemp and Schmetterer 2008). Hence, measurements of oxygen levels in retinal vessels are needed to further our understanding of these ischemic diseases. It is a well known fact and a commonly employed method to measure oxygen saturation of blood through light transmission (Kramer 1934). However, this approach is not feasible in the human eye. Therefore, reflection must be used, meaning the amount of incident light must be estimated based on the amount of light reflected (for a review see Harris 2003). This is a difficult task and investigators in this field have encountered several problems, including optical complexities, nonlinear sensors and eye movement (Beach et al 1999; Delori 1988). Nonetheless considerable progress has been made over the past decades and the development of an reliable oximeter reported (Hardarson et al 2006). In the present study this technique will be applied in healthy subjects as well as in patients with COPD during room-air conditions. The procedure takes approximately 15 minutes in each subject and will be performed in only one eye.

NCT ID: NCT00998660 Completed - Parkinson's Disease Clinical Trials

RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR)

RECHARGE
Start date: July 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the recharge feature of the Activa RC System in patients who are receiving Deep Brain Stimulation (DBS) for Parkinson's Disease (PD), Essential Tremor (ET), or dystonia.

NCT ID: NCT00997997 Completed - Clinical trials for Skin Diseases, Bacterial

Avelox in Complicated Skin and Skin Structure Infections

ARTOS
Start date: October 2005
Phase: N/A
Study type: Observational

This international, prospective, non-interventional, non-controlled observational study obtains data on efficacy, safety and tolerability of Avelox treatment under daily-life treatment conditions. Specifically investigated are the improvement of clinical symptoms and the duration until infection improvement and cure.Any patient with a diagnosis of complicated skin and skin structure infection (cSSSI) treated with Avelox can be documented. The observation period for each subject covers the treatment period with Avelox. For each patient, the physician documents data at an initial visit and one or two follow-up visit(s) in line with routine practice.

NCT ID: NCT00997204 Completed - Clinical trials for Hereditary Angioedema

EASSI - Evaluation of the Safety of Self-Administration With Icatibant

EASSI
Start date: September 25, 2009
Phase: Phase 3
Study type: Interventional

This study is being conducted to explore the clinical safety, local tolerability, convenience and effectiveness of self-treatment of hereditary angioedema (HAE) attacks with subcutaneous injections of icatibant.

NCT ID: NCT00997061 Completed - Clinical trials for Lung Cancer, Small Cell

SCOT Registry: Small Cell Lung Cancer Treatment and Outcome

SCOT
Start date: November 2009
Phase: N/A
Study type: Observational

The registry is an international, multicenter, observational registry of newly diagnosed patients with SCLC. Data will be entered into an electronic CRF (eCRF) via Internet access. Treatment plan remains the responsibility of the patient's physician and data collected in this registry will reflect a "real world" approach of the diagnosis and treatment of patients with SCLC. Approximately 60 centres in 13 countries will take part in this registry. It is expected that about 500 patients will be recruited during a period of 6 to 9 months according to the feasibility.

NCT ID: NCT00996281 Completed - Clinical trials for Essential Hypertension

Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential Hypertension

Start date: October 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and tolerability of azilsartan medoxomil plus chlorthalidone, once daily (QD), versus olmesartan medoxomil-hydrochlorothiazide in adults with essential hypertension.

NCT ID: NCT00996177 Completed - Pain Clinical Trials

A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or Intravenously

EuroTrans
Start date: June 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of a patient-controlled system to deliver fentanyl compared with a patient-controlled intravenous system to deliver morphine in the management of postoperative pain.

NCT ID: NCT00994318 Completed - Clinical trials for Chronic Kidney Disease

Ferric Carboxymaltose (FCM) Assessment in Subjects With Iron Deficiency Anaemia and Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

FIND-CKD
Start date: December 2009
Phase: Phase 3
Study type: Interventional

Phase IIIb study to evaluate the long-term efficacy of ferric carboxymaltose (FCM) (using targeted ferritin levels to determine dosing) or oral iron in non-dialysis-dependent chronic kidney disease (NDD-CKD) subjects with iron deficiency anaemia (IDA).