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NCT ID: NCT00311090 Completed - Clinical trials for Deep Venous Thrombosis

Bioequipotency Study of SSR126517E and Idraparinux in Patients With Deep Venous Thrombosis of the Lower Limbs

EQUINOX
Start date: April 2006
Phase: Phase 3
Study type: Interventional

The three purposes of this study are the following: - To compare during a 6-month treatment the safety and effectiveness of idrabiotaparinux (SSR126517) with that of idraparinux (SR34006), taking into account new events of deep venous thrombosis (DVT) and pulmonary embolism (PE), and bleeding risk; - To compare the activities of idrabiotaparinux and idraparinux directly in blood during and after a 6-month treatment; - To check the ability of avidin (SSR29261) to reverse the blood thinning activity of idrabiotaparinux at the end of a 6-month treatment period.

NCT ID: NCT00310843 Completed - HIV Infections Clinical Trials

Case-Control Viramune (Nevirapine) Toxicogenomics Study

Start date: February 2006
Phase: Phase 4
Study type: Observational

Attempt to identify genetic polymorphisms in interrogated pathways which may be associated with symptomatic hepatotoxicity or severe cutaneous toxicity observed in case patients within the first 8 weeks of nevirapine therapy.

NCT ID: NCT00310544 Completed - Clinical trials for Myocardial Infarction

Depiction of Delayed Enhancement in Patients With Documented Myocardial Infarction

Start date: March 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the dose of drug which is most effective in the delineation of dead heart muscle.

NCT ID: NCT00310375 Completed - Epilepsy Clinical Trials

Open-label Extension Study of the Phase 3 VRX-RET-E22-301 Double-Blind Trial

Start date: May 1, 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of long-term therapy with retigabine administered as adjunctive therapy in adult epilepsy patients with partial-onset seizures, who completed the VRX-RET-E22-301 double-blind study. The efficacy of long-term treatment with retigabine and patient quality of life will also be assessed.

NCT ID: NCT00309244 Completed - Diabetes Type 2 Clinical Trials

Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial Inhalation of Technosphere/Insulin Versus Subcutaneous Premixed Insulin Therapy Over a 52-Week Treatment Period and a 4-Week Follow-up

Start date: February 2006
Phase: Phase 3
Study type: Interventional

The purpose of this 13 month study (12 month treatment period and 1 month follow-up period) is to determine whether inhaled insulin is safe and effective in the treatment of type 2 diabetes.

NCT ID: NCT00308308 Completed - Diabetes, Type I Clinical Trials

Efficacy & Safety of Inhaled Insulin in Type 1 Diabetes

Start date: February 2006
Phase: Phase 3
Study type: Interventional

To determine the safety and efficacy of inhaled insulin in the treatment of type 1 diabetes

NCT ID: NCT00306956 Completed - Sudden Infant Death Clinical Trials

Influence of Pacifiers on Breastfeeding Duration

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the introduction of pacifier use to infants at 2 weeks of age, once breast feedings are well established, will affect the incidence and duration of successful breastfeedings.

NCT ID: NCT00306384 Completed - Diabetes Mellitus Clinical Trials

Long-term Safety of Alogliptin in Patients With Type 2 Diabetes Mellitus

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of alogliptin, once daily (QD), following participation in 1 of 7 controlled studies in patients with type 2 diabetes mellitus.

NCT ID: NCT00305461 Completed - Asthma Clinical Trials

Effect of Ciclesonide on Quality of Life in Patients With Moderate Persistent Asthma (21 to 65 y) (BY9010/AR-101)

Start date: February 2006
Phase: Phase 3
Study type: Interventional

The aim of the study is to compare the effect of ciclesonide on quality of life, pulmonary function and time to first exacerbation in patients with moderate persistent asthma. Ciclesonide will be administered once daily in the evening at two dose levels. The study duration consists of a baseline period (2 weeks) and a treatment period (8 weeks).

NCT ID: NCT00305188 Completed - Clinical trials for Colorectal Neoplasms

Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.

Start date: December 2005
Phase: Phase 3
Study type: Interventional

Primary Objective : Compare the risk of occurrence of Grade3-4 cumulative peripheral sensory neuropathy (PSN) relative to cumulative dose of oxaliplatin between treatment group and placebo group. Main Secondary Objective : Compare the response rate (RR) between treatment group and placebo group in order to ensure that the efficacy of the chemotherapy is not compromised by the addition of xaliproden to the chemotherapeutic regimen. Other Secondary Objectives : study of the neurotoxicity parameters (Duration of oxaliplatin-induced PSN (G2,3,4); overall incidence of PSN during treatment; dose of onset of PSN ; incidence of dose-reduction and dose delay due to PSN; incidence of oxaliplatin treatment discontinuation due to PSN; change in Nerve Conduction Studies (NCS)) ; study of the safety profile (other than PSN) ; study of the chemotherapy efficacy (progression free survival, overall survival).