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NCT ID: NCT01076582 Completed - Oral Contraceptive Clinical Trials

Comparative Trial in Hormone Withdrawal Associated Symptoms

Start date: April 2010
Phase: Phase 3
Study type: Interventional

This clinical research study will examine whether an oral contraceptive pill taken with a monthly hormone-free interval of 4 days reduces hormone withdrawal associated symptoms compared to an oral contraceptive pill taken with a monthly hormone-free interval of 7 days after 4 cycles of treatment.

NCT ID: NCT01075737 Completed - Multiple Sclerosis Clinical Trials

An Observational Study to Assess the Quality of Life of the Patients With Multiple Sclerosis and Their Caregivers

Start date: August 2008
Phase: N/A
Study type: Observational

This is an observational, non controlled, non-interventional, multicentric, prospective study planned to be conducted in 450 subjects diagnosed with MS and their caregivers in 20 centres of Argentina. The observations from this study will contribute to the awareness of the impact on the Quality of Life (QoL) of the caregivers and, eventually will also provide measures for helping the subjects with multiple sclerosis (MS) without leaving aside the care of the physical and psychic health of those who work as caregivers.

NCT ID: NCT01075282 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)

AWARD-2
Start date: February 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if LY2189265 is effective in reducing hemoglobin A1c (HbA1c) and safe, as compared to Insulin Glargine in participants with Type 2 Diabetes. Participants must also be taking metformin and glimepiride.

NCT ID: NCT01073488 Completed - Clinical trials for Maternal Morbidity and Mortality

Emergency Obstetric and Neonatal Care: The EmONC Trial

EmONC
Start date: December 2008
Phase: N/A
Study type: Interventional

The objective of this cluster randomized controlled trial is to reduce maternal and neonatal mortality by increasing access to and improving the quality of obstetric and neonatal care for pregnant women in study clusters. It is hypothesized that a 25% reduction in >28 week or >1000 gram stillbirth and 7-day neonatal mortality will be achieved in the intervention clusters by a multifaceted Emergency Obstetric Neonatal Care (EmONC) package that will be introduced by an EmONC team.

NCT ID: NCT01072630 Completed - Depression Clinical Trials

Study to Evaluate the Efficacy and Safety of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Start date: March 2010
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to determine whether armodafinil treatment, at a dosage of 150 mg/day, is more effective than placebo treatment as adjunctive therapy to mood stabilizers for treatment of adults with major depression associated with bipolar I disorder.

NCT ID: NCT01069900 Completed - Clinical trials for Intraabdominal Infections

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

MOXIPEDIA
Start date: July 21, 2010
Phase: Phase 3
Study type: Interventional

The primary focus of the study is the evaluation of the safety of treatment with moxifloxacin in a pediatric population 3 months to <18 years old. Approximately 450 pediatric subjects with a complicated intra-abdominal infection will be enrolled in the study and treated with either moxifloxacin intravenously and orally if switched to oral therapy or ertapenem (intravenously) and, if switched to oral therapy, amoxicillin/clavulanate.

NCT ID: NCT01068704 Completed - Breast Cancer Clinical Trials

Efficacy and Safety of BMS-690514 in Combination With Letrozole to Treat Metastatic Breast Cancer

Start date: June 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if BMS-690514 + letrozole will be more effective than lapatinib + letrozole in patients who have metastatic hormone receptor positive breast cancer after developing progressive disease immediately following adjuvant antiendocrine therapy

NCT ID: NCT01067976 Completed - Breast Cancer Clinical Trials

Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast MRI

Start date: February 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to look at the efficacy (how does it work) and safety of gadobutrol when used for obtaining MR images of both breasts.Women with a recent diagnosis of breast cancer by mammogram (X-ray examination of the breasts) may benefit from MRI of the breasts as MRI may detect additional breast cancers.

NCT ID: NCT01067859 Terminated - Acute Heart Failure Clinical Trials

A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

COMPOSE 2
Start date: March 2010
Phase: Phase 2
Study type: Interventional

A placebo controlled, double-blind and randomized study to assess different doses of a new drug (BAY58-2667) given intravenously, to evaluate if it is safe and can help to improve the well-being of patients with acute decompensated heart failure.

NCT ID: NCT01067820 Completed - Clinical trials for Coronary Artery Disease

ApoA-I Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation

ASSURE I
Start date: September 2011
Phase: Phase 2
Study type: Interventional

This study is designed to characterize the early effects of ApoA-I synthesis with RVX000222 on coronary atherosclerotic disease when administered to patients with coronary artery disease and have a low HDL-C level, as assessed by Intravascular Ultrasound (IVUS) in addition to standard background therapy.