Coronary Artery Disease Clinical Trial
Official title:
Effects of a Personalized Training Program on Trans-thoracic Adenosine-assisted Coronary Flow Reserve in Healthy Volunteers
This study investigates whether an individualized exercise program, including a personal trainer, can improve cardiovascular status quantified with ultrasound to assess coronary flow reserve and other non-invasive techniques. The subjects in the study will be divided into two groups; one group will have a personalized exercise- and nutrition program and the other group will have acess to a gym membership, but no personal trainer.
Coronary heart disease is one of our most common diseases that causes significant morbidity
and mortality. Because the risk of serious cardiovascular events, such as myocardial
infarction and death, is evident in this patient population, it is of utmost importance to
develop diagnostic methods to identify patients at risk. The most appropriate diagnostic
methods are those that are safe to implement for both patient and physician, but also
accessible and cost-efficient.
By using non-invasive techniques such as ultrasound, coronary artery function can be examined
as coronary flow reserve (CFR). In the platform of non-invasive techniques used by the
investigators for examinations of cardiovascular status, other methods are included, such as
measurement of intima-media thickness in the carotid and radial arteries. The investigators
goal is to compare the group with the personalized program with its placebo, and to compare
the two study-groups with each other, to investigate whether the personalized program
provides greater health benefits.
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