Coronary Artery Disease Clinical Trial
Official title:
Is There an Association Between the Presence of Diabetes, the Degree of Arterial Stiffness and a New Plasma Marker for Vascular Elasticity, Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and
these patients, as a consequence herby, has a lesser prognosis. DM is often related to
increased arterial stiffness and hypertension. The investigators thesis is that DM and
pre-diabetes is prevalent in patients undergoing cardiovascular surgery and to some extend
is under-diagnosed. At the same time the investigators imagine that DM is closely related to
the degree of arterial stiffness, and that these parameters are closely related to a new
biochemical marker, fibulin-1.
The investigators aim to describe the prevalence of type 2 DM and dysmetabolism in patients
admitted to the hospital to undergo cardiovascular surgery and besides that to investigate
if there is a connection between the degree of the dysmetabolism and arterial disease, by
studying arterial stiffness and by measuring a new biochemical marker, fibulin-1, which the
investigators newly have identified. The results of this project will give us a measure for
the quantity of unknown DM in patients undergoing cardiovascular surgery and furthermore
tell us more in terms of the connections between a newly identified plasma arterial marker,
arterial stiffness and diabetes.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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