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Carotid Stenosis clinical trials

View clinical trials related to Carotid Stenosis.

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NCT ID: NCT03672955 Active, not recruiting - Clinical trials for Internal Carotid Artery Stenosis With Infarction

Advanced Ultrasound Methods in the Assessment of Carotid Plaque Instability

Start date: September 1, 2016
Study type: Observational

The primary aim of this project is to assess if advanced ultrasound methods such as SMI (Superb microvascular Imaging) and SWE (Shear Wave Elastography) can identify intraplaque neovascularization and plaque tissue stiffness in carotid artery plaques and relate these results to ipsilateral cerebrovascular symptoms. The secondary aim of this project is to assess the level of agreement between the structural plaque characteristics assessed by advanced ultrasound examinations such as SMI, SWE, CEUS (Contrast enhanced ultrasound), GSM (Plaque gray-scale-median) and carotid MRI, metabolic activity of plaque assessed by 18F-FDG PET/CT with histology as the gold standard. Findings from the methods mentioned above will be related to cerebrovascular symptoms, blood tests (cholesterol-tot, LDL, HDL, CRP, leukocytes, glucose, HbA1c) and other cardiovascular risk factors at inclusion and upon 1 year follow up.

NCT ID: NCT03631381 Recruiting - Carotid Stenosis Clinical Trials

Retrospective Study of Carotid Surgery in Dijon

Start date: September 4, 2017
Study type: Observational

The results in carotid surgery are an indicator of the functioning of an academic surgical team, making it possible to evaluate and improve practices, as much among surgeons in training as among senior surgeons. The indications have evolved with the development of symptomatic stenosis surgery, and results analysis has allowed us to improve our practices. It would be of great use to have the statistics obtained in previous years to continue improving our practices.

NCT ID: NCT03596229 Not yet recruiting - Carotid Stenosis Clinical Trials

Major Adverse Cardiac Events After Carotid Endarterectomy

Start date: October 1, 2018
Study type: Observational

Carotid endarterectomy is the operation for curing the significant carotid artery stenotic patients who are also at high cardiac risk. This retrospective study is to find out the incidence and risk factors related.

NCT ID: NCT03587324 Completed - Clinical trials for Vascular Surgery Patient With PAD / Carotid Stenosis

Perioperative Aspirin Response in Patients Undergoing Vascular Surgery

Start date: February 2013
Phase: N/A
Study type: Interventional

Reduced antiplatelet activity (low response (LR)/high on-treatment platelet reactivity (HPR)) of aspirin (ALR) or clopidogrel (CLR) is associated with an increased risk of thromboembolic events. The prevalence figures for low-responders reported in the literature vary widely and there have been few investigations in vascular surgery patients to date. The aim of this prospective monocentric study was to increase the evidence base on vascular surgery patients and to detect any changes in the response following vascular surgery procedures.

NCT ID: NCT03516929 Recruiting - Clinical trials for Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to Coronary Artery Bypass Surgery

Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG

Start date: April 5, 2018
Phase: N/A
Study type: Interventional

From our experience among Egyptian population in our institution, there is an increased prevalence of hidden subclinical peripheral artery disease along with carotid artery affection. Thus, increasing the risk of post-operative morbid complications.We aim to evaluate routine/ non-selective carotid and peripheral arterial screening in asymptomatic patients undergoing coronary artery bypass grafting in the Egyptian populationIt is a prospective, non-randomized, comparative study including two groups of patients. The study will start from the day of approval of the ethical committee. It will include 260 patients, on basis of "all new comers". Patients will be examined and classified as "high-risk" group (ɳ = 130) or "low-risk" group (ɳ=130). All patients will have the "routine" preoperative investigations along with evaluation of extracranial carotid system by non-invasive carotid duplex and lower limb arterial system by non-invasive bilateral lower limb arterial duplex.

NCT ID: NCT03504228 Recruiting - Clinical trials for Carotid Artery Stenosis

Observational Study to Confirm Safety and Efficacy of the ROADSAVER Stent for the Treatment of Carotid Artery Stenosis

Start date: January 23, 2018
Study type: Observational

Approximately 2000 patients eligible for elective treatment with a Carotid Stent according to hospital routine practice in centers across Europe will be enrolled in the study. The maximum number of patients enrolled at each site will be not limited. Follow-ups are scheduled at discharge, 30 days, and 1 year, as per local practice. Each patient will have follow-up contacts via hospital visit and/or telephone.

NCT ID: NCT03495830 Recruiting - Clinical trials for Carotid Artery Stenosis

Stratification of Patient With Carotid Disease

Start date: March 29, 2018
Study type: Observational

Introduction: Taxinomisis trial is part of the Taxinomisis project. The concept of the Taxinomisis project is to stratify carotid artery disease relying on new modern data corresponding to contemporary patients based on information from longitudinal studies. Taxinomisis trial will validate this tool and adjust such stratification. Initial step of the project is characterization of symptomatic and asymptomatic carotid atherosclerotic plaque lesions, identification of risk and susceptibility factors through the exploitation of longitudinal cohort data and multiomics and disintegration of carotid artery disease phenotypes into endotypes through joint modeling of multipleomics data sets and systems medicine approaches. Finally such stratification model will be validated and adjusted in the Taxinomisis clinical trial.

NCT ID: NCT03488199 Recruiting - Clinical trials for Patients With Aterosclerotic Carotid Stenosis

The SIBERIA Trial (Acculink™ Versus CGuard™)

Start date: September 11, 2017
Phase: N/A
Study type: Interventional

That the study will be carried out as it has the protocol instructions, respecting the applicable regulations for clinical investigations with medical devices and following the internationally accepted ethical standards

NCT ID: NCT03464851 Recruiting - Clinical trials for Carotid Artery Stenosis

Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis

Start date: March 8, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA) as compared to a carotid ultrasound study.

NCT ID: NCT03419767 Recruiting - Carotid Stenosis Clinical Trials

Insulin Resistance in Patients After Carotid Revascularization

Start date: August 1, 2017
Phase: Phase 4
Study type: Interventional

The main purpose of this study is to study the phenomenon of insulin resistance in patients after carotid revascularization surgery through population-based, randomized, double-blind, placebo-controlled trial.