Coronary Artery Disease Clinical Trial
Official title:
Phase II Trial of Sleep Apnea Treatment to Reduce Cardiovascular Morbidity
This study examines the role of sleep apnea treatment in improving cardiovascular biomarkers.
This is a Phase II randomized controlled trial that will evaluate the effects of
supplemental nocturnal oxygen or Positive Airway Pressure (PAP) therapy, compared to optimal
medical preventive therapy for Cardiovascular Disease (CVD) risk, on biomarkers of CVD risk
in Obstructive Sleep Apnea (OSA) patients at high risk for CVD events. The study will focus
on patients with moderate to severe OSA but only mild OSA symptoms.
Eligible participants have a history or symptoms of heart disease AND have symptoms of sleep
apnea or snoring. Participants will be contributing to medical knowledge about different
options that can be used to improve heart disease in people with sleep apnea.
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Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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