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Clinical Trial Summary

the purpose of this study is to show that alirocumab with statin therapy have a s tronger stabilizing effect on vulnerable plaque in coronary artery disease than statin alone administration


Clinical Trial Description

The investigators investigate to evaluate the efficacy of alirocumab for vulnerable plaque. The investigators enrolled the patient with standard statin therapy who were detected vulnerable plaque by optical coherence tomography, and categorized into two group; the patients with alirocumab and rosuvastatin were categorized alirocumab therapy group, and the patients with rosuvastatin alone were categorized standard statin therapy group. The investigators compare these two group for outcomes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03552432
Study type Interventional
Source Kobe University
Contact Hiromasa Otake, M.D, Ph,D
Phone +81-78-382-5846
Email hotake@med.kobe-u.ac.jp
Status Recruiting
Phase Phase 4
Start date September 26, 2017
Completion date September 30, 2021

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