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Chronic Disease clinical trials

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NCT ID: NCT05075551 Active, not recruiting - Clinical trials for Chronic Prostatitis With Chronic Pelvic Pain Syndrome

Analyzing the Brain Alterations of Acupuncture on Patients With CP/CPPS Evaluated by fMRI

Start date: January 5, 2022
Phase: N/A
Study type: Interventional

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the most common diseases in urology, but its pathogenesis remains unclear and the effective therapy lacks. As a kind of chronic pain which the patients suffered for more than 3 months, CP/CPPS could be alleviated by acupuncture. Functional magnetic resonance imaging (fMRI) and higher magnetic field strengths could enable scientists to investigate the brain accurately and non-invasively during every stage of chronic pain.To avoid placebo effect, sham acupuncture would be also enrolled.Herein, by the utilization of fMRI in resting-state, we investigated the influence on patients' brain alterations after the patients accepted the treatment of acupuncture.

NCT ID: NCT05075096 Completed - Covid19 Clinical Trials

Long Term Outcome in ICU Treated COVID-19: New Chronic Diseases

Start date: October 15, 2021
Phase:
Study type: Observational

Additional chronic diseases one year after intensive care unit (ICU) admission with Coronavirus disease 2019 (COVID-19) will be assessed in comparison to two control cohorts. The ICU population comprises all Swedish ICU patients with COVID-19 with at least one year of follow up. The hospital admitted cohort comprises four hospital admitted patients with COVID-19 per ICU patient, matched on age, legal gender and region. The general population controls are matched to the ICU patients in a one to four fashion on age, legal gender and region. ICU patients are identified in the Swedish intensive care registry. The hospital admitted patients are identified in the national patient registry and the population controls are identified in the population registry. Data on comorbidity, medications and death are provided from the National board of health and welfare.

NCT ID: NCT05062850 Recruiting - Clinical trials for The Study Addressed the Most Common Geriatric Syndromes and Chronic Diseases at Age 90 Years and Older and Their Association

Between Geriatric Syndrome and Chronic Disease Association and Prevalence Among Nonagenarians

Start date: September 1, 2021
Phase:
Study type: Observational [Patient Registry]

OBJECTİVE The world population is getting older. The most common condition in the aging population is comorbidity, which is a combination of more than one chronic disease or condition. Contrary to the traditional view that specific symptoms are characteristic of a single disease, the coexistence of multiple diseases and other age-related conditions in elderly individuals leads to what is defined as geriatric syndromes. Geriatric syndromes are quite common in the elderly population and are associated with poor quality of life, adverse health status, and increased cost. Physicians who more frequently care and manage patients with comorbid diseases and geriatric syndrome can cope better with these conditions when faced with them. It is known that the frequency of comorbidity and geriatric syndrome increases especially in the elderly. However, in the oldest age group, which is showing the fastest increase in population, these rates are not clearly known. The aim of this study is to shed light on the management of elderly patients by identifying geriatric syndromes and comorbidity prevalence, as well as chronic diseases and common geriatric syndromes, in patients 90 years of age and older who applied to the geriatric outpatient clinic. METHOD Data of patients 90 years and older who applied to the geriatric outpatient clinic between November 2016 and January 2020 were retrospectively analyzed. The drugs used by the patients with their demographic characteristics such as age, gender, chronic diseases and geriatric syndromes were gathered. The drugs used were also obtained from the hospital-registered files and through the E-Pulse health system. Diabetes mellitus (DM), hypertension (HT), cardiovascular diseases (CVD), cerebrovascular occlusion (CVO), chronic obstructive pulmonary disease (COPD), chronic kidney disease (CKD) were recorded as chronic diseases. Mild cognitive impairment (MCI), dementia, delirium, depression, fall, incontinence, malnutrition, sleep disorders, polypharmacy, and fall were recorded as geriatric syndrome. The modified Charlson comorbidity index was used to calculate the comorbidity index.

NCT ID: NCT05056493 Enrolling by invitation - Clinical trials for Children/Youth With Special Healthcare Needs

Caremap: A Digital Personal Health Record for Complex Care Coordination

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This study will implement a new mobile application ('app') called Caremap to improve care coordination for patients with complex health needs. The goal is to pilot test the mobile app with patients/families and clinic doctors to gather input on how well the app works and how to make it better. Investigators plan to enroll up to 40 participants from Duke University for this study. The study is sponsored by Duke's Institute for Health Innovation.

NCT ID: NCT05039216 Recruiting - Clinical trials for Rheumatoid Arthritis

Biobank for Inflammatory Chronic Diseases and Osteoporosis

BIOTOUL
Start date: September 13, 2021
Phase:
Study type: Observational

The aim of this study is to constitute a biobank for patients followed in the Rheumatology center of Toulouse University Hospital for a chronic inflammatory rheumatism including rheumatoid arthritis (RA), spondyloarthritis(SpA), and psoriatic arthritis (PsA) or a chronic bone disease including osteoporosis in order to identify biomarkers associated with therapeutic response.

NCT ID: NCT05025579 Completed - Depression Clinical Trials

What is the Effect of Aerobic Exercise on Depression in Geriatric Individuals Diagnosed With Depression?

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

This study was planned to examine the effect of aerobic exercises on depression in geriatric individuals with a diagnosis of depression.

NCT ID: NCT05021835 Recruiting - Inflammation Clinical Trials

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

ZEUS
Start date: August 30, 2021
Phase: Phase 3
Study type: Interventional

This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). This is known as the study medicine. Which treatment participants get is decided by chance. Participants chance of getting ziltivekimab or placebo is the same. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine doctors cannot prescribe. Participants will get the study medicine in a pre filled syringe. Participants will need to use the pre filled syringe to inject the study medicine into a skinfold once-monthly. The study is expected to last for up to 4 years. Participants will have up to 20 clinic visits. Participants will have blood and urine samples taken at most of the clinic visits. Participants will have their heart examined using sound waves (echocardiography) and electrodes (electrocardiogram). Women cannot take part if pregnant, breast-feeding or planning to get pregnant during the study period.

NCT ID: NCT05006560 Recruiting - Clinical trials for Pulmonary Disease, Chronic Obstructive

Internet-based Rehabilitation Aftercare Focusing on Physical Activity Promotion in Persons With COPD

COPD-AReNa
Start date: July 5, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate a 12-week internet-based rehabilitation aftercare program with an emphasis on physical activity promotion for persons with COPD. The program starts directly after an inpatient pulmonary rehabilitation program. It includes monitoring and promotion of physical activity, progressive resistance and endurance training, education through online learning modules and continuous support from a therapist.

NCT ID: NCT05001256 Completed - Obesity Clinical Trials

Determination of Physical Activity Status and Adherence to the Mediterranean Diet in Adults and Related Health Outcomes

Start date: July 15, 2021
Phase:
Study type: Observational

A physically active life with adequate and balanced nutrition is essential for a healthy life. Unhealthy diet and being physically inactive are among the common risk factors that need to be corrected in order to maintain and improve health. The Mediterranean diet, first described by Angel Keys, is rich in plant foods such as grains, fruits, vegetables, legumes, oilseeds and olives; The main source of added oils is olive oil; moderate-high consumption of fish and seafood, moderate-level consumption of eggs, poultry and dairy products, and low-level red meat; It is a nutrition model with moderate intake of wine / fermented beverages (such as turnip, grape juice). Preferring vegetable oils instead of animal fats, preferring fish instead of red meat consumption, preferring low-fat / fat-free milk and dairy products, limiting the intake of simple sugar and refined carbohydrates, fruit rich in fiber and antioxidants in the Mediterranean diet, which is shown as an example of healthy nutrition today. It is thought that this type of nutrition can prevent the formation of chronic diseases due to features such as increasing vegetable consumption. Determining the nutritional status and physical activity levels of individuals and their associated health outcomes; It is very important in terms of determining the current situation and determining the priority problems that need to be solved.

NCT ID: NCT05000619 Completed - Prevention Clinical Trials

Encouraging Overdue Healthcare Appointment Scheduling Among Patients With Chronic Diseases

Start date: July 12, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to determine the most effective messages for encouraging patients with chronic conditions, who have not seen their doctor in at least one year, to return to the clinic. Study participants will receive postcards or letters encouraging them to make an appointment. Researchers will assess whether messages increase appointment scheduling (and attendance).