Cardiovascular Diseases Clinical Trial
Official title:
Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC
To investigate the role of racial and socioeconomic disparities in coronary heart disease (CHD) mortality in the United States.
BACKGROUND:
Despite strong decreases in coronary heart disease (CHD) mortality over past decades, there
is evidence that racial and socioeconomic disparities in CHD mortality are increasing. CHD
surveillance efforts that examine trends within these population subgroups are an important
first step in quantifying and reducing disparities. The Atherosclerosis Risk in Communities
(ARIC) Study has monitored rates and trends in validated hospitalized myocardial infarction
and fatal CHD among black and white adults aged 35 to 74 years in four U.S. communities
since 1989.
DESIGN NARRATIVE:
The study will expand the scope of ARIC surveillance by examining variations in the rates
and temporal trends in CHD by socioeconomic status (SES), measured at the level of census
tract. For CHD events already included in ARIC surveillance (1992-2002), addresses will be
obtained from medical records and death certificates and geocoded so that they can be
matched with identifiers for census based geographical areas. The ARIC study will contribute
yearly updates of abstracted CHD events and addresses for subsequent years (2003-2005). Each
event will be linked with census tract level SES indicators available from the 1990 and 2000
censuses. This novel effort will permit an examination of disparities by SES in rates and
trends in fatal CHD, hospitalized myocardial infarction, case fatality, use of invasive
cardiac procedures and prescription of efficacious medication at time of hospital discharge.
In addition, the extent to which racial disparities in CHD and associated treatments are
explained by SES will also be explored.
;
Time Perspective: Retrospective
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