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Cancer clinical trials

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NCT ID: NCT04066868 Recruiting - Cancer Clinical Trials

Evaluating the Use of Patient-Reported Outcome Measures for Improving the Inter-Rater Reliability of Common Terminology Criteria for Adverse Event Ratings

Start date: February 10, 2020
Phase: N/A
Study type: Interventional

This open randomized trial investigates, if clinicians complete CTCAE ratings differently when receiving patients' patient-reported outcome (PRO) data prior to their CTCAE completion. The primary objective is to demonstrate superior inter-rater reliability of CTCAE ratings from physicians relying on EORTC PRO data as additional data source over traditional CTCAE ratings not including PRO information.

NCT ID: NCT04066153 Completed - Cancer Clinical Trials

Patient Reported Unmet Needs for Function and Supportive Occupational- and Physiotherapy Rehabilitation Interventions

Start date: August 20, 2019
Phase:
Study type: Observational

Purpose: To determine unmet functional needs in patients referred to the Palliative Care Unit at Rigshospitalet, Copenhagen University Hospital will be asked to fill out self reported questionnaires regarding problem intensity, problem burden and felt needs, physical functioning, emotional functioning, fatigue, sleep, distress. Furthermore patients physical function will be evaluated.

NCT ID: NCT04065815 Recruiting - Cancer Clinical Trials

Protein-rich Nutritional Therapy Combined With Time-efficient Exercise in Cancer Therapy

PROTECT
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study aims to evaluate the effects of a 12-week protein-rich individualized nutritional therapy combined with different time-efficient exercise programs on overall physical fitness (cardiorespiratory fitness and muscular fitness), inflammation, and muscle mass/body composition in patients with malignant disease undergoing curative or palliative anti-cancer treatment

NCT ID: NCT04065542 Recruiting - Cancer Clinical Trials

Determinants of Health and Cancer: Investigating the Conceptions of Children From 6 to 11 Years Old

FCE
Start date: January 1, 2019
Phase:
Study type: Observational

Model and map, from a qualitative multi-phased protocol, the conceptions and systems of conceptions of the determinants of health and cancer expressed and perceived by schoolchildren aged 6 to 11 years. The secondary objectives are to analyze the ability to question the conceptions of children's health regardless of their age and to link conceptions and determinants to contextual factors. The informative value and complementarity of the collection tools (photo expression, QC, photo-narration) and the relevance of a mixed analysis methodology (qualitative and quantitative) in order to highlight the different determinants of health will also be studied.

NCT ID: NCT04061902 Completed - Cancer Clinical Trials

Participation in Surgical Cancer Care

Particip
Start date: December 1, 2016
Phase:
Study type: Observational

Patients that are involved in their health care is associated with improved treatment outcomes, rehabilitation and recovery. In this research project we aim to assess patient participation among patients who had surgery for liver, bile duct (cholangiocarcinoma) and pancreatic cancer and follow a fast-track recovery program.

NCT ID: NCT04060706 Recruiting - Cancer Clinical Trials

Heuristics, Algorithms and Machine Learning: Evaluation & Testing in Radiation Therapy

Hamlet rt
Start date: September 11, 2019
Phase:
Study type: Observational [Patient Registry]

The Hamlet.rt study is a prospective data collection and patient questionnaire study for patients undergoing image-guided radiotherapy with curative intent. The aim of the study is to use novel machine learning and mathematical techniques to build a model that can predict the risk of significant side effects from radiotherapy treatment for an individual patient: using calculations of normal tissue dose from radiotherapy treatment planning and patient baseline characteristics derived from image and non-image data, continuously updated as the patient is reviewed both during and after treatment. A secondary goal of the project is to facilitate research in machine learning and medical image processing for radiation therapy through the creation of a discoverable and shared data resource for research use.

NCT ID: NCT04060290 Completed - Cancer Clinical Trials

Real-world Study for the Safety of Albumin-Bound Paclitaxel in Malignant Tumors

Start date: May 12, 2020
Phase:
Study type: Observational

This is a multi-center, Prospective, observational study,to evaluate the safety and influencing factors of albumin-bound paclitaxel in the real-world chinese population,and evaluate of the efficacy of albumin-bound paclitaxel in patients with malignant tumors and its impact on quality of life.

NCT ID: NCT04059588 Completed - Cancer Clinical Trials

A Study Investigating the Safety and Tolerability of an Immune Treatment in Cancer Patients With Lesions to the Skin

Start date: January 16, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the safety and tolerability of 2141-V11 in people who have cancer that does not respond to standard treatment and who have skin lesions (skin tumors) associated with their cancer. The study will also test how the body processes and responds to 2141-V11, and if the study drug has cancer fighting activity in people. The study drug activates a naturally occurring protein called CD40. By activating CD40, cells of the immune system are better able to identify and kill cancer cells. We are testing if injection of 2141-V11 into metastasis to the skin will be safe and well tolerated, and may result in immune activation in patients with solid tumors that have metastasis to the skin.

NCT ID: NCT04059237 Completed - Cancer Clinical Trials

Pilot Study of a Decision Aid Intervention for Family-building After Cancer

Start date: January 6, 2020
Phase: N/A
Study type: Interventional

This study tests a web-based decision aid and planning too to help young female cancer survivors manage fertility and family-building issues in post treatment survivorship.

NCT ID: NCT04058795 Recruiting - Cancer Clinical Trials

PTSD Mobile App for Cancer Survivors

Start date: January 24, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to use a stepped-care approach in treating symptoms of posttraumatic stress disorder (PTSD). The information learned by doing this study may help us to develop some target treatments for PTSD symptoms in survivors of stem cell transplant. Participants in this study will be randomized to a mobile app or usual care. An assessment will be made after 4 weeks and a determination made of adding more intensive treatment. Participants will be asked to complete a questionnaire 4 times over a period of 6 months, at the time your participation is complete.