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NCT ID: NCT00034307 Active, not recruiting - Clinical trials for Pulmonary Hypertension

Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension

Start date: n/a
Phase: Phase 2/Phase 3
Study type: Interventional

This is a clinical research study designed to evaluate an investigational new medication called sitaxsentan for the treatment of pulmonary arterial hypertension (patients with NYHA functional class II, III or IV). The purpose of this study is to evaluate the safety and effectiveness of two different doses of sitaxsentan, compared to placebo (inactive treatment) for the treatment of pulmonary arterial hypertension. Patients who complete this trial may be eligible to take part in an extension trial (Protocol FPH01-X). Eligible patients who receive placebo in the 12-week study cross over to receive sitaxsentan for the extension trial.

NCT ID: NCT00037089 Active, not recruiting - Esophageal Neoplasm Clinical Trials

A Phase II Study of Paclitaxel, UFT, and Leucovorin in Patients With Metastatic Esophageal Cancer

Start date: n/a
Phase: Phase 2
Study type: Interventional

This study is for patients with esophageal cancer that has spread to other areas. The purpose of this study is to: 1. Determine how well a combination of taxol, UFT, and leucovorin work in these patients, 2. Determine the survival of patients with metastatic esophageal carcinoma treated with this combination of drugs. 3. Identify the side effects of this drug combination.

NCT ID: NCT00038753 Active, not recruiting - Amblyopia Clinical Trials

Vision In Preschoolers Study (VIP Study)

Start date: n/a
Phase: Phase 3
Study type: Interventional

To identify vision-screening tests that can accurately predict those three- and four-year old preschoolers who would benefit from a comprehensive vision examination because of signs of amblyopia, strabismus, and/or significant refractive error.

NCT ID: NCT00040430 Active, not recruiting - Breast Cancer Clinical Trials

Study of 111In-DAC as a Medical Imaging Agent for the Detection of Breast Cancer

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the safety and imaging ability of 111In-DAC when used with planar and SPECT imaging for the detection of breast cancer.

NCT ID: NCT00040560 Active, not recruiting - Clinical trials for Carcinoma, Non-Small-Cell Lung

Study of 111In-DAC as an Medical Imaging Agent for Lung Cancer and Brain Cancer Consistent With Metastatic Lung Cancer

Start date: n/a
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the safety and imaging ability of 111In-DAC when used with planar and SPECT imaging for the detection of lung cancer and brain cancer consistent with metastatic lung cancer.

NCT ID: NCT00043199 Active, not recruiting - Clinical trials for Colorectal Neoplasms

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Start date: n/a
Phase: Phase 2
Study type: Interventional

To determine the rate of response and duration of reponse following therapy with Aroplatin in subjects with advanced colorectal cancer resistant to standard therapies. Secondary objectives are to determine safety and tolerability of the Aroplatin therapy.

NCT ID: NCT00043797 Active, not recruiting - Clinical trials for Diabetic Polyneuropathy

Lidorestat (IDD 676) for the Treatment of Diabetic Neuropathy

Start date: n/a
Phase: Phase 2
Study type: Interventional

This clinical trial is to determine an effective dosage and to study the safety of an investigational drug -lidorestat (IDD-676)- which is intended to stop or slow the progression of diabetic peripheral neuropathy.

NCT ID: NCT00048217 Active, not recruiting - HIV Infections Clinical Trials

A Rollover Study to Provide Chronic T-1249 to Patients Who Completed Study T1249-102

Start date: n/a
Phase: Phase 1/Phase 2
Study type: Interventional

Patients who complete study T1249-102 (must be currently failing a T-20 containing regimen to participate in this study) will receive T-1249 at a dose of 200mg daily in combination with a background antiretroviral regimen for 96 weeks. Only patients that participated in study T1249-102 can participate in study T1249-105.

NCT ID: NCT00052130 Active, not recruiting - Malignant Melanoma Clinical Trials

Vaccine Therapy for Patients With Stage III Melanoma

Start date: n/a
Phase: Phase 3
Study type: Interventional

This is a Phase 3 study in patients with melanoma that has spread to the lymph nodes (stage III), and who have had all of their cancer surgically removed. The purpose of this study is to evaluate the ability of the CancerVax™ vaccine to prevent or slow the recurrence of melanoma.

NCT ID: NCT00052156 Active, not recruiting - Malignant Melanoma Clinical Trials

Vaccine Therapy for Patients With Stage IV Melanoma

Start date: n/a
Phase: Phase 3
Study type: Interventional

This is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed. The purpose of this study is to evaluate the ability of the CancerVax™ vaccine to prevent or slow the recurrence of melanoma.