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NCT ID: NCT00368173 Completed - Laron Syndrome Clinical Trials

IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome

Start date: n/a
Phase: Phase 2/Phase 3
Study type: Interventional

STUDY OBJECTIVE To evaluate the safety, tolerability, and efficacy, as growth velocity (statural growth), of rhIGF-I/rhIGFBP-3 administered for 12 months in pre-pubertal children and adolescents with GHIS. STUDY DESIGN This study is an open-label, multi-center clinical trial to evaluate the safety and effectiveness of rhIGF-I/rhIGFBP-3 to increase rate of growth when administered once daily for 12 months in children and adolescents with growth hormone insensitivity syndrome (GHIS) such as Laron Syndrome. At the end of the initial twelve-month treatment period, additional safety and long-term efficacy data will be assessed in a second 12 month treatment period.

NCT ID: NCT00368342 Completed - Asthma Clinical Trials

Chronic Bronchiolitis or Resistant Asthma?

Start date: n/a
Phase: Phase 4
Study type: Interventional

Chronic Bronchiolitis or Resistant Asthma? Testing a way to diagnosis and treatment

NCT ID: NCT00373906 Completed - MALT Lymphoma Clinical Trials

Velcade in MALT Lymphoma Patients

Start date: n/a
Phase: Phase 2
Study type: Interventional

Bortezomib for treatment of disseminated MALT lymphoma or at relapse following HP -eradication,or chemotherapy or radiation.

NCT ID: NCT00374504 Completed - Cesarean Section Clinical Trials

Prediction of Postoperative Pain by an Electrical Pain Stimulus

Start date: n/a
Phase: N/A
Study type: Observational

The aim of this study is to evaluate a possible correlation between predictive precesarean section pain and development of postcaesarean section pain using the PM. Patients and Methods 46 healthy pregnant women scheduled for elective cesarean section is included after informed consent. The standard operation procedures included spinal anesthesia, paracetamol 1 g 8 hourly, diclofenac 50 mg 8 hourly and oxycontine 10 mg x 2. Morphine was used for break-through pain. Before cesarian section the threshold for sensory and pain were measured 3 times, and the average was used for analyses. After cesarian section a blinded midwife assess the pain at rest and during mobilization every 12th hours over 2 days score. Data was analyzed using AUC and non-parametric test, P < 0,05.

NCT ID: NCT00375323 Completed - Hemophilia A Clinical Trials

Recombinant Factor VIIa (NovoSeven) on Restoring Coagulation Activation

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the effects of recombinant factor VIIa (NovoSeven) on restoring coagulation activation between patients with hemophilia A and antibodies to factor VIII and normal subjects (controls) by use of an in vivo method.

NCT ID: NCT00376610 Completed - Bearings Clinical Trials

Prospective Clinical Evaluation of ASR/Re-Cap Resurfacing Arthroplasty

Start date: n/a
Phase: Phase 4
Study type: Interventional

ASR/Re-cap versus 28 MoM

NCT ID: NCT00376857 Completed - Clinical trials for Idiopathic Epiretinal Membrane, Cataract

Surgical Removal of Idiopathic Epiretinal Membrane With and Without the Assistance of Indocyanine Green.

Start date: n/a
Phase: N/A
Study type: Interventional

It was the aim of the present study to prospectively compare the functional and morphological outcome of idiopathic epiretinal membrane surgery with and without the assistance of Indocyanine green (ICG). The main outcome measure was improvement of best-corrected visual acuity (BCVA). This was treated as an open question and we had no hypothesis which of the two therapies was superior.

NCT ID: NCT00377169 Completed - HIV Infections Clinical Trials

Collection of Blood Samples From SMART Study Participants for Future Genetic Studies

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this study is to collect blood samples from SMART study participants to use in future genetic studies.

NCT ID: NCT00377546 Completed - Vitrectomy Clinical Trials

Comparison of Vitreous Levels of Acular LS 0.04%, Xibrom 0.09%, and Nevanac 0.1%

Start date: n/a
Phase: Phase 4
Study type: Interventional

To compare the penetration of three different NSAIDs.

NCT ID: NCT00378456 Completed - Clinical trials for Trisiomy 21 (Down Syndrome)

Vitamins and Minerals for Children With Downs Syndrome

Start date: n/a
Phase: N/A
Study type: Interventional

The trial aimed to examine the effects of supplementation with antioxidants and folinic acid on the health, growth and psychomotor development of children with Down syndrome. 156 children with Trisomy 21, less than 7 months of age were recruited and randomised into four groups to receive antioxidants, folinic acid, a combination of antioxidants and folinic acid or a placebo. Blinded outcome assessment was carried out 18 months later.Blood and urine samples were also taken around 12 months of age to examine metabolic effects of supplementation.