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NCT ID: NCT03685188 Enrolling by invitation - Clinical trials for Analgesia, Patient-Controlled

Oxycodone and Sufentanil for Analgesia in Hip Surgery

Start date: December 1, 2018
Phase: Phase 4
Study type: Interventional

We design this randomized controlled trial to compare the safety and efficacy of Oxycodone and Sufentanil for postoperative patient-controlled analgesia in patients undergoing hip surgery, with a view to finding the optimal postoperative analgesic regime with fewer adverse reactions and promoting patients' rehabilitation.

NCT ID: NCT03768011 Enrolling by invitation - Pain, Chronic Clinical Trials

Subjective Observational Study of Patients Using Transdermal Cream Medication And/Or Transdermal Patches With Or Without Oral Non-Narcotic Medications

Start date: December 1, 2018
Phase:
Study type: Observational

purpose of this study is to evaluate the level of pain perceived by patients using a transdermal cream and/or transdermal patch with or without an oral medication as a pain management solution.

NCT ID: NCT03781024 Enrolling by invitation - Diabetic Foot Ulcer Clinical Trials

A Subjective Observational Study of Patients Using Medicated Footbath/Footwash Treatment in Podiatry Care

Start date: December 1, 2018
Phase:
Study type: Observational

The purpose of this study is to evaluate the level of relief perceived by patients using medicated footbath/footwash with or without an oral medication for the treatment of podiatry issues.

NCT ID: NCT03827512 Enrolling by invitation - Clinical trials for French Vascular Physicians

Arterial Doppler Waveforms Analysis in PAD

APP-Wave-PAD
Start date: December 1, 2018
Phase:
Study type: Observational

The main objective is to evaluate the differences of terminology used when describing arterial doppler waveforms. To assess the impact of an educational process

NCT ID: NCT03862274 Enrolling by invitation - Batten Disease Clinical Trials

Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease

Start date: December 1, 2018
Phase:
Study type: Observational

The investigators propose a study to assess cognitive and developmental outcomes of patients with CLN2 that are untreated and receiving cerliponase alfa. This study aims to validate standardized assessment measures to establish a standard of care. The secondary aim is to compare cognitive and developmental outcomes of patients with CLN2 that are receiving celiponase alfa to a natural history cohort. To accomplish specific aims of the study, the investigators will use a multi-method approach to collect retrospective data collected as standard of care and prospective developmental data in children with CLN2 disease. The investigators will use a combination of standardized measures that include direct assessment and parent report of child development. The investigators focus will also include multiple measures of development including language, motor, social-emotional, and adaptive functioning.

NCT ID: NCT03911362 Enrolling by invitation - Clinical trials for Stress Urinary Incontinence

A Comparison of Lumbopelvic Stabilisation and Pelvic Floor Exercises on the Stress Incontinence

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The patients diagnosed with stress urinary incontinence and included in the study. According to randomisation plan one group will be instructed by a physiotherapist to perform pelvic flor exercises and the other group will be instructed by the same physiotherapist to perform dynamic lumbopelvic stabilisation exercises.Throughout the study, the women will be followed up to ensure the exercises are performed. The exercises will be applied for approximately 30 mins once a day for a period of 10 weeks.

NCT ID: NCT03964935 Enrolling by invitation - Periodontal Pocket Clinical Trials

Lycopene vs Minocycline Hydrochloride as Adjunctive to Periodontal Treatment

Start date: December 1, 2018
Phase: Phase 2
Study type: Interventional

Periodontal diseases are among the most common medical conditions that may influence humans; 50% of the adult population can be affected by this illness. The condition is usually initiated by lack or reduction in oral hygiene which is then aggravated by the presence of microorganisms within biofilm which will induce a sequel of events that will lead to periodontitis. Scaling, root planning, and polishing (SRP) are the golden standard procedures in the treatment. Systemic antibiotics as adjunctive therapy has been established to be an excellent modality in controlling the bacterial virulence, hence, supporting the conventional SRP therapy. in order to avoid and limit the harmful effect of systemic antibiotics different locally applied preparations have been introduced including antioxidants. The aim of this prospective clinical study is to compare between the effect of Minocycline hydrochloride (HCL) microsphere and Lycopene gel when they are applied intrapocket subgingival with conventional SRP therapy

NCT ID: NCT04312880 Enrolling by invitation - Spine Surgery Clinical Trials

Tranexamic Acid Infusion During Elective Spine Surgery

Start date: December 1, 2018
Phase: Phase 4
Study type: Interventional

Tranexamic acid (TXA) is an agent that has been shown to be safe and effective to reduce blood loss in surgical procedures. The purpose of the study is to assess the effect of transexamic on elective decompressive lumbar spine surgery with and without fusion.

NCT ID: NCT04520347 Enrolling by invitation - Clinical trials for Ventricular Tachycardia

IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

IVTCC
Start date: December 1, 2018
Phase:
Study type: Observational [Patient Registry]

This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular Contractions (PVC). The registry will be used for clinical monitoring, research, and quality improvement purposes.

NCT ID: NCT05543304 Enrolling by invitation - Effect of Drug Clinical Trials

Predicting Response to Systemic Therapies for Hepatocellular Carcinoma(HCC)

Start date: December 1, 2018
Phase:
Study type: Observational

As the most common type of primary liver cancer, hepatocellular carcinoma (HCC) has become a big challenge all over the world. Most patients are not available to curative resection when first diagnosed. There are a variety of treatment options for advanced HCC. However, due to the heterogeneity of HCC, the overall response rate (ORR) is not high for systemic therapies. Therefore, appropriate selection of patients who are suitable for individual systemic therapies is important for clinical decision-making.