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Brain Tumor clinical trials

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NCT ID: NCT04463979 Recruiting - Brain Tumor Clinical Trials

Perioperative Evaluation of Cerebellar Tumors

Start date: February 28, 2021
Phase:
Study type: Observational

This is a prospective, cohort study to evaluate the impact of cerebellar functional topography on perioperative outcomes related to cognition and motor ataxia in patients with cerebellar tumors.

NCT ID: NCT04446416 Completed - Neoplasms Clinical Trials

Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients

Start date: July 21, 2020
Phase: N/A
Study type: Interventional

This is a prospective, single-arm, two stages, open-label, pilot study to investigate the efficacy and safety of FUS add-on bevacizumab (BEV) in rGBM patients. The BEV is the best physician's choice of standard of care for rGBM after prior radiotherapy and temozolomide chemotherapy in the LinKou Chang Gung Memorial Hospital. Eligible patients will be enrolled through the process of informed consent.

NCT ID: NCT04427384 Recruiting - Brain Tumor Clinical Trials

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

Start date: September 11, 2020
Phase:
Study type: Observational [Patient Registry]

The objectives of this registry study are to evaluate real-world clinical outcomes and patient reported outcomes that measure the effectiveness and safety of STaRT.

NCT ID: NCT04410315 Completed - Surgery Clinical Trials

Hyperlactatemia During and After Tumorcraniotomy

Start date: July 28, 2020
Phase:
Study type: Observational

This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy. The risk factors that induce lactat accumulation will also be explored.

NCT ID: NCT04334863 Completed - Brain Tumor Clinical Trials

WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors

Start date: May 4, 2020
Phase: Phase 1
Study type: Interventional

In this Phase I clinical study, the investigators plan to offer investigational treatment with the novel JAK2/STAT3 inhibitor WP1066 (Moleculin Biotech, Inc.) to pediatric patients with any progressive or recurrent malignant brain tumor that is refractory to standard treatment and is without known cure.

NCT ID: NCT04322734 Not yet recruiting - Epilepsy Clinical Trials

Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

Start date: July 1, 2024
Phase:
Study type: Observational

Researchers in the Neurodevelopmental Division at Phoenix Children's Hospital are conducting a study about mitochondrial function in children with autism spectrum disorder (ASD). The study involves up to 5 visits to Phoenix Children's Hospital with fasting blood draws, behavioral assessments, and/or questionnaires. Other samples may be collected when appropriate. This study is currently recruiting. There is no cost for visits or study-related exams.

NCT ID: NCT04320108 Recruiting - Stroke Clinical Trials

ESWT for Shoulder Pain in Patients With Brain Damage

Start date: May 29, 2020
Phase: N/A
Study type: Interventional

This study aimed to investigate the efficacy and safety of extracorporeal shockwave therapy (ESWT) for upper extremity pain related to spasticity in patients with spinal cord injury.

NCT ID: NCT04306484 Completed - Brain Tumor Clinical Trials

18F-DOPA-PET in Non-tumoral and Tumoral Brain Lesions

FDOPA
Start date: January 1, 2020
Phase:
Study type: Observational

Background: 3,4-dihydroxy-6-[18F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (PET) can identify well low and high grade brain tumors. However, increased FDOPA uptake has been reported in non-tumoral brain lesions. The aim was to analyse FDOPA-PET in patients with non-tumoral brain lesions and to compare them with patients with (low and high grade) brain tumors. Methods: retrospective analyse. Patients consecutively recruited with suspected primary brain tumor (based on clinical and MRI findings) referred for FDOPA-PET at Nimes university Hospital between June 2015 and June 2019. FDOPA-PET parameters (maximum and mean lesion standardized uptake values [SUV] and ratios comparing lesion with different background uptake SUV) and thresholds were analysed in search for those offering optimal discrimination between non-tumoral and tumoral lesions.

NCT ID: NCT04292353 Active, not recruiting - Clinical trials for Cognitive Impairment

Cerebral Morbidity After Radiation Therapy for Brain Tumors

WP-12
Start date: July 1, 2016
Phase:
Study type: Observational

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.

NCT ID: NCT04288505 Recruiting - Brain Tumor Clinical Trials

Evaluation of a Virtual Reality Tool for Identifying the Cognitive Functions of the Right Hemisphere in Patients With Glioma -TANGO

TANGO
Start date: May 28, 2020
Phase: N/A
Study type: Interventional

Evaluate the diagnostic performance of a virtual reality application to detect the presence of cognitive impairment of the non-dominant hemisphere in patients with glioma