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Brain Tumor clinical trials

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NCT ID: NCT04699773 Recruiting - Glioblastoma Clinical Trials

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

Start date: February 20, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with newly diagnosed gliomas.

NCT ID: NCT04692337 Recruiting - Brain Tumor Clinical Trials

Ommaya Reservoir Placement for Brain Tumor Biomarker Access

Start date: January 15, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and feasibility of intra-operative Ommaya Reservoir placement during a clinically indicated operation for brain tumor. The Ommaya reservoir will facilitate a longitudinal access to cerebrospinal fluid (CSF) for analysis of potential biomarkers for brain tumor research and individualized monitoring.

NCT ID: NCT04634188 Completed - Brain Tumor Clinical Trials

Role and Value of Inflammatory Markers in Brain Tumors : A Case Controlled Study

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

This study is a case controlled analytical study that analyzes the relationship between levels of inflammatory markers with the type of brain tumor. Samples of 35 people were then categorized according to the variables above and analyzing to measure its significance

NCT ID: NCT04585633 Recruiting - Anesthesia Clinical Trials

Postoperative Risk Prediction Score After Elective Intracranial Neurosurgery Operation

Start date: July 1, 2022
Phase:
Study type: Observational

The aim of our study is to prevent unnecessary intensive care unit hospitalizations by developing a scoring system to detect low-risk patients after elective intracranial neurosurgery operation.

NCT ID: NCT04584827 Completed - Brain Tumor Clinical Trials

Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy

Start date: December 10, 2019
Phase:
Study type: Observational

The aim of this study is to determine the effects of the level of metabolites used in routine on mortality and morbidity in patients who will undergo intracranial surgery with craniotomy.

NCT ID: NCT04553549 Completed - Stroke, Acute Clinical Trials

Safety and Feasibility of the Infinity Catheter for Radial Access

Start date: October 1, 2020
Phase:
Study type: Observational

The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial approach through a secondary use of the data collected during neurointerventional procedures. This includes evaluating the conversion rates to a transfemoral approach. A secondary aim of the study is to assess the radial artery occlusion rates post procedure.

NCT ID: NCT04536142 Completed - Brain Tumor Clinical Trials

Evaluation of Changes in Brain Connectivity After Tumor Resection

Start date: August 27, 2020
Phase:
Study type: Observational

This study is being done to see the changes in structural and functional connectivity that happen in the brain of patients undergoing brain tumor surgery.

NCT ID: NCT04490954 Active, not recruiting - Brain Tumor Clinical Trials

The Accuracy of Brain Biological Electrical Impedance Tomography Screen for Supratentorial Tumors

ABST
Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Compared with MRI or CT, brain biological electrical impedance tomography were performed on patients with supratentorial tumors and healthy people . The AUC (area under the curve) of ROC, which is associated with the increased maximum and the difference between left and right equilibrium of impedance value, is calculated. The specificity of brain biological electrical impedance tomography in screening supratentorial tumors are evaluated. To compare the changes of parameters detected by brain biological electrical impedance tomography, the enrolled brain tumor patients with cerebral edema were paired with themselves and intravenous infusion of mannitol so that the sensitivity of this device in monitoring cerebral edema can be evaluated.

NCT ID: NCT04479241 Active, not recruiting - Glioblastoma Clinical Trials

LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma

Start date: October 21, 2020
Phase: Phase 2
Study type: Interventional

This Phase 2 single arm trial in patients with rGBM will characterize the efficacy, safety, tolerability and initial efficacy of lerapolturev intratumoral infusion followed by intravenous pembrolizumab 14 to 28 days later, and every 3 weeks, thereafter.

NCT ID: NCT04474678 Completed - Leukemia Clinical Trials

Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")

Start date: September 7, 2020
Phase: N/A
Study type: Interventional

In this study, the main goal is to implement and evaluate a novel, evidence-based psycho-educative program for children in oncological care. Patients are provided with booklets tailored to each specific stage of their treatment. Among other factors, children's emotional well-being is evaluated as well as feasibility. The study is carried out at multiple sites across Austria, Germany and Italy/South Tirol.