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Brain Tumor clinical trials

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NCT ID: NCT06257498 Completed - Brain Tumor Clinical Trials

Upright Open MRI for Brain Imaging in Children - a Pilot Study

Heads-Up
Start date: January 25, 2022
Phase: N/A
Study type: Interventional

PRIMARY OBJECTIVE To establish feasibility and acceptability of diagnostic brain MRI in young children for specified indications using an upright MRI system without sedation or anaesthesia. SECONDARY OBJECTIVES To establish how young children who undergo brain MRI using upright MRI view the experience To establish how parents / carers of young children who undergo brain MRI using the upright MRI view the experience for their child and for themselves. To establish how image quality compares between brain MRI using the upright MRI scanner and the standard MRI scanner used in clinical practice.

NCT ID: NCT06251830 Completed - Multiple Sclerosis Clinical Trials

Increasing Diagnosis Rates While Reducing Examination Time: Can MR Fingerprinting Deliver on Its Promise?

Start date: September 1, 2018
Phase:
Study type: Observational

Magnetic Resonance Imaging (MRI) is an excellent method for diagnosis and staging of brain disease. However, lengthy scan times and sensitivity to patient motion limit its efficacy. To address this, a novel method has recently been demonstrated, called MR Fingerprinting (MRF). The investigators' improved implementation of MRF, featuring fully-quantitative data and a reduced sensitivity to patient motion, can be used to acquire an anatomical exam in less than five minutes at a standard resolution. The potential for wide applicability of this technique, combined with an implied reduction in complexity and cost of MRI exams, has generated wide interest. However, published studies have been limited to demonstrations in healthy volunteers, and the effectiveness of MRF in the clinical practice has not yet been proven. Here, the investigators aim to assess the efficacy of MRF in performing diagnostic exams avoiding sedation in children and for increasing diagnosis rates in challenging adult patients.

NCT ID: NCT05288088 Completed - Brain Tumor Clinical Trials

Why Still in Neurosurgical Ward After Tumor Craniotomy?

Start date: June 12, 2022
Phase:
Study type: Observational

The aim of this prospective observational study is to identify the specific reasons that prolong a hospital stay after elective tumor craniotomy. Optimal postoperative in-hospital stay is considered to be two days from surgery to discharge from the neurosurgical ward. However, a variable length of stay at a neurological department for follow-up of late recognized deficits of neurological consequences of the surgical procedure are common.

NCT ID: NCT05145049 Completed - Brain Tumor Clinical Trials

The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies

Start date: November 1, 2021
Phase:
Study type: Observational [Patient Registry]

The investigators aimed to research the incidence of hyperlactatemia in craniotomy cases, the relationship of lactate elevation with tumor type and other factors that may be related, and whether the general anesthesia method applied (inhalation anesthesia or total ıntravenous anesthesia) affects lactate level.

NCT ID: NCT05065268 Completed - Brain Tumor Clinical Trials

Visual Rehabilitation in Children With Homonymous Hemianopia: a Pilot Study on Virtual-reality Stimulation

HH-IVR
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

There are currently no visual rehabilitation strategies for children presenting visual field defects consecutive to a brain tumor or its treatment. This study seeks to investigate the use of a home-based stimulation visual rehabilitation program using immerse-virtual reality (IVR) in children aged 4-10 years old with a diagnosis of hemianopia

NCT ID: NCT05039346 Completed - Quality of Life Clinical Trials

Quality of Life and Patient Needs in Advanced High Grade Gliomas

Start date: February 11, 2012
Phase:
Study type: Observational

There is limited knowledge regarding the quality of life and needs of patients with advanced high grade gliomas, especially during the end of life. By doing this research, we are able to assess caregiver and patient symptoms and needs during the end of life phase of patients with brain tumors.

NCT ID: NCT04768400 Completed - Brain Tumor Clinical Trials

MEP and Neuromuscular Blocker

Start date: March 9, 2021
Phase: N/A
Study type: Interventional

It is important to predict the influence of the neuromuscular blocking agents on the motor evoked potential. Investigator will investigate the dose-response relationship between the degree of the neuromuscular blockade and the motor evoked potential in patients undergoing brain tumor surgery using the population approach. Investigator will investigate the influence of the other factors such as the impedence, reactance, muscel amount, and age on the motor evoked potential.

NCT ID: NCT04634188 Completed - Brain Tumor Clinical Trials

Role and Value of Inflammatory Markers in Brain Tumors : A Case Controlled Study

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

This study is a case controlled analytical study that analyzes the relationship between levels of inflammatory markers with the type of brain tumor. Samples of 35 people were then categorized according to the variables above and analyzing to measure its significance

NCT ID: NCT04584827 Completed - Brain Tumor Clinical Trials

Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy

Start date: December 10, 2019
Phase:
Study type: Observational

The aim of this study is to determine the effects of the level of metabolites used in routine on mortality and morbidity in patients who will undergo intracranial surgery with craniotomy.

NCT ID: NCT04553549 Completed - Stroke, Acute Clinical Trials

Safety and Feasibility of the Infinity Catheter for Radial Access

Start date: October 1, 2020
Phase:
Study type: Observational

The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial approach through a secondary use of the data collected during neurointerventional procedures. This includes evaluating the conversion rates to a transfemoral approach. A secondary aim of the study is to assess the radial artery occlusion rates post procedure.