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Body Weight clinical trials

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NCT ID: NCT04340388 Completed - Vascular Diseases Clinical Trials

Contribution of Dolutegravir to Obesity and Cardiovascular Disease

Start date: September 17, 2020
Phase: Phase 4
Study type: Interventional

The goal of the study is to combine a collaborative and translational approach to evaluate the effect antiretroviral regimen switch to a dolutegravir containing regimen compared to continued treatment with a non- dolutegravir based regimen on on lipid and metabolic profiles, renal function, body composition, vascular function and diet.

NCT ID: NCT04337619 Active, not recruiting - Obesity Clinical Trials

Project Activate: Mindfulness and Acceptance Based Behavioral Treatment for Weight Loss

Activate
Start date: August 15, 2019
Phase: N/A
Study type: Interventional

Mindfulness and Acceptance based Behavioral Therapies (MABTs) are among the most promising behavioral approaches for obesity, with two recent large trials showing that they achieve better initial weight loss and/or better weight loss maintenance than does gold standard BT. However, results vary, potentially due to inconsistencies in how MABT components are utilized and emphasized. Optimizing MABTs using a typical approach, i.e., successive randomized controlled trials of various MABT packages, is slow and difficult. Multiphase Optimization Strategy (MOST) has been developed as a better method of optimizing treatment. Consistent with Phase I of MOST, we derived three MABT components from the theoretical literature. Evaluation of MABT components through a factorial design (MOST Phase II) will allow us to determine the independent and interacting efficacies of each MABT component, in addition to the identification of subsets of individuals most or least responsive to each component. Whereas mediational analyses have been inconclusive, the use of a factorial design will allow for a critical test of the main and interaction effects of individual MABT treatment components. The current study will use a full factorial design to identify the independent and combined effects of three core MABT components (Awareness, Acceptance, and Values Clarity) as additions to remotely delivered weight loss counseling. Moderators of treatment outcome (disinhibited eating, food cue susceptibility, emotional eating, delay discounting, and inhibitory control), and mediator/process variables implicated in MABTs (mindful eating, acceptance of food cues, mindfulness, body responsiveness, autonomous motivation, values clarity, hunger/satiety perceptions, and motivation and pleasure resulting from social functioning) will be assessed as well.

NCT ID: NCT04330976 Completed - Clinical trials for Gestational Weight Gain

Preventing Excessive Gestational Weight Gain Via Short Mobile Messages in WIC

Start date: October 30, 2017
Phase: N/A
Study type: Interventional

The objective of this trial was to investigate the effect of educational short message service (SMS), or text messages, on gestational weight gain (GWG) in a low-income population.

NCT ID: NCT04330391 Active, not recruiting - Weight Loss Clinical Trials

Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this trial is to assess the impact of a 12-week remote dietitian supervised dietary and physical activity weight loss intervention and mobile app for patients with morbid obesity prior to undergoing total joint arthroplasty of the hip or knee. The hypothesis is that that the intervention will result in: 1) greater weight loss than usual care, 2) a higher percentage of patients eligible to undergo surgery by having a body mass index (BMI) below the standard cutoff of 40 kg/m2, and 3) a higher percentage of patients undergoing surgery within six months of study enrollment.

NCT ID: NCT04330209 Completed - Weight Loss Clinical Trials

Comparing a Low-GI Nutrigenetic and Ketogenic Diet for Weight Loss With 18 Month Follow-up

LOWGI_GENE
Start date: January 1, 2014
Phase:
Study type: Observational

The investigators followed a convenience sample of 114 overweight and obese subjects from a weight loss clinic who followed a 24-week dietary intervention. The subjects self-selected whether to follow a standardized ketogenic diet (n=53), or a personalised low-glycemic index (GI) diet utilising information from 28 single nucleotide polymorphisms (n=61). After the 24-week study period, the subjects were monitored for an additional 18 months.

NCT ID: NCT04317079 Completed - Body Weight Clinical Trials

Effects of Hydroxytyrosol Administration in Anthropometric Parameters in Overweight and Obese Women

Start date: October 30, 2017
Phase: N/A
Study type: Interventional

This study aims to investigate the potential effects of the administration of hydroxytyrosol, which is an extra virgin olive oil phenolic compound, in doses 15 milligrams and 5 milligrams daily versus placebo for 6 months in anthropometric parameters such as body weight, body fat and visceral fat, in combination with diet, in overweight and obese women.

NCT ID: NCT04313478 Completed - Early Intervention Clinical Trials

The Relationship Between Segmental Trunk Control and Gross Motor Performance in Low Birth Weight Born Infant

Start date: May 1, 2013
Phase:
Study type: Observational

This study aimed to examine the relation between trunk control and gross motor performance in LBW and NBW infants.

NCT ID: NCT04311450 Completed - Clinical trials for Overweight and Obesity

Behavioral Weight Loss Treatment for Individuals With Food Addiction

FA Pilot
Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this research study is to examine how well an existing weight loss treatment works for individuals with food addiction. Treatment will consist of a preliminary 12-week RCT pilot of the feasibility and effectiveness of behavioral weight loss (BWL) compared to a waitlist control.

NCT ID: NCT04306315 Recruiting - Psoriasis Vulgaris Clinical Trials

Adjusted Brodalumab Dose Compared With Standard Brodalumab Dose in Subjects With Moderate-to-severe Plaque Psoriasis and ≥120 kg Body Weight

ADJUST
Start date: July 18, 2022
Phase: Phase 4
Study type: Interventional

This study investigates if an adjusted brodalumab dosage regimen will give improved efficacy in psoriasis in patients with a body weight of over 120 kg. The increased dosage regimen will be compared to the standard brodalumab treatment plus placebo.

NCT ID: NCT04302389 Active, not recruiting - Weight Loss Clinical Trials

Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program

Start date: February 10, 2021
Phase: N/A
Study type: Interventional

The goal of the proposed research project is to evaluate the acceptability and efficacy of an online multicomponent commercial weight loss program and to understand the relationship between program engagement and weight loss and health outcomes.