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Anxiety Disorders clinical trials

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NCT ID: NCT02376959 Recruiting - Anxiety Disorders Clinical Trials

Effect of Spiritist "Passe" Energy Therapy in Reducing Anxiety in Volunteers

Start date: September 2014
Phase: N/A
Study type: Interventional

Background: The use of alternative therapies in medicine has been increasing worldwide. Among these therapies are energy therapies such as Reiki , Johrei, and Spiritist "passe." Experimental studies have confirmed the action of the energy therapies in animal models or in cell cultures. These therapies appear to have positive effects, particularly in the reduction of anxiety and pain. Objective: To evaluate the effectiveness of the "passe" energy therapy in reducing anxiety in subjects presenting anxiety symptoms after 8 weeks of study. Methods: The recruited volunteers will be randomized into two groups: the Control Group (application of 8 "passe" simulation sessions by people without spiritualist training at the same time and in the same environment as the treatment group) and the Treatment Group (application of 8 sessions of "passe" by spiritists with over 2 years of experience in controlled environments for the same period as the control group). The sample will consist of 60 patients selected by interviews with the expectation of a 20% reduction of anxiety in the control group and 60% in the treatment group with alpha of 0.05 and beta of 0.8. Results: Using the STAI scale for evaluation, the reduction in anxiety is expected to be significantly higher in the treatment group than in the control group. The investigators expect approximately 20-30% reduction of the anxiety in the control group by the placebo effect. Other objectives to be assessed are quality of life, spirituality, and depression by specific standardized scales (WHOQOL-BREF, DUREL, and BECK).

NCT ID: NCT02374567 Terminated - Depression Clinical Trials

Pharmacovigilance in Gerontopsychiatric Patients

GAP
Start date: January 2015
Phase: Phase 3
Study type: Interventional

The purpose of this multicenter-study is to investigate safety of psychopharmacological treatment and rates of adverse drug reactions in gerontopsychiatric inpatients. Elderly people are at higher risk for developing side effects under pharmacological treatment due to an altered metabolic situation, higher comorbidity rates and often polypharmacy. Furthermore gerontopsychiatric patients can often not articulate their symptoms clearly, for example due to pronounced cognitive impairment. The aim of the study is to gain valid data of possible adverse drug reaction rates, their potential risk factors and outcome, as well as medical prescription practises. To assess these outcomes an intensive pharmacovigilance-monitoring will be conducted at the five participating study sites. At Baseline demographic data, previous and present disorders, use of drugs, previous and present medication, quality of life, cognitive function, physical examination results, laboratory results and ECG will be assessed. Afterwards patients are visited weekly and screened for possible adverse drug reactions. All adverse drug reactions will be coded in the MedDRA-system. In case of a possible serious adverse drug reaction serum levels of all psychotropic substances applicated will be assessed. Drug combinations will be analysed using an established advanced bioinformatic tool (mediQ). Diagnosis, medication intake and possible adverse drug reactions are documented continually. 2 weeks after discharge from the ward, patients will be contacted by phone to assess catamnestic data.

NCT ID: NCT02372110 Completed - Anxiety Clinical Trials

Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response

Start date: March 2015
Phase: Phase 4
Study type: Interventional

The proposed study aims to investigate experimentally anxiety sensitivity and physiologic sensations associated with anxiety using a paradigm combining hydrocortisone, caffeine, and a set of social stress challenges. Following informed consent, participants will be instructed to ingest either 400 milligrams of caffeine (an amount of caffeine roughly equivalent to that in two 8 oz. cups of brewed coffee from Starbucks), and 20 milligrams of hydrocortisone or two placebo capsules via stratified, random assignment. Physiologic and self-reported measures of stress and anxiety will be taken.

NCT ID: NCT02372019 Completed - Clinical trials for Social Anxiety Disorder

Augmentation Study of A Computerized Treatment for Social Anxiety Disorder

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether briefly reactivating a fear memory 10 minutes prior to administering a social anxiety treatment will enhance the durability of treatment effects.

NCT ID: NCT02371954 Completed - Depression Clinical Trials

Exercise to Prevent Depression and Anxiety in Older Hispanics

Start date: September 2013
Phase: N/A
Study type: Interventional

The study is a randomized pilot trial of a health promotion intervention in the prevention of anxiety and depression in older Hispanics.

NCT ID: NCT02366390 Completed - Anxiety Clinical Trials

Dialogue Aimed at Reducing Anxiety in Patients With Severe COPD

DIACOL
Start date: February 2015
Phase: Phase 4
Study type: Interventional

The purpose of this trial is to determine whether a minimal homebased psychoeducative intervention is effective in management of anxiety and dyspnea in patients with severe chronic obstructive pulmonary disease.

NCT ID: NCT02365870 Terminated - Parkinson Disease Clinical Trials

Anxiety in Parkinson's: Use of Quantitative Methods to Guide Rational Treatment

ANXPD
Start date: August 2016
Phase: Phase 4
Study type: Interventional

This study will evaluate the effectiveness of the rotigotine transdermal patch in reducing anxiety in people with Parkinson's disease.

NCT ID: NCT02361190 Completed - Anxiety Clinical Trials

Effects of Fast Acting Testosterone Nasal Spray on Anxiety

Start date: February 2015
Phase: N/A
Study type: Interventional

The proposed study will test the effects of a fast-acting testosterone nasal spray on the fear reactions of young men to two distinct anxiety challenges (social and nonsocial) using a double-blind randomized experimental design.

NCT ID: NCT02360033 Completed - Clinical trials for Social Anxiety Disorder

Systemic Therapy and Cognitive Behavioral Therapy for Social Anxiety Disorders

Start date: January 2015
Phase: N/A
Study type: Interventional

Goals of the study: Systemic Therapy was approved in 2008 by the Scientific Advisory Board on Psychotherapy (Wissenschaftlicher Beirat Psychotherapie: WBP) for a variety of disorders which, at the time, did not include anxiety disorders. According to the 2007 joint methods paper of the WBP and the Mutual Federal Committee (Gemeinsamen Bundesausschuss: G-Ba), there must be three randomized-controlled trials (RCT) for anxiety disorders. These studies are available now but lack explicit details about the clinical significance of the reductions they show in social anxiety symptoms. This project is funded by the German Association for Systemic Therapy, Counseling and Family Therapy (Deutsche Gesellschaft für Systemische Therapie, Beratung und Familientherapie: DGSF). Study design: The study is planned as a mono-centric, balanced pilot RCT. It investigates the feasibility of an RCT comparing Systemic Therapy and Cognitive Behavioral Therapy for Social Anxiety Disorders (SAD) in 32 patients.

NCT ID: NCT02355626 Completed - Anxiety Clinical Trials

Prognosis of Anxiety in Intensive Care Unit

PAN-ICU
Start date: April 2014
Phase:
Study type: Observational

Anxiety is commonly considered as an epiphenomenon of the cognitive and emotional response to a threat. Anxiety is a consequence of the reciprocal interaction between stress and the neuroendocrine, autonomic and immune systems. A systematic and circumstantial assessment of anxiety in critically ill patients has never been done. Our hypothesis is that high levels of anxiety at ICU admission are associated with death or the occurrence of one or more organ failure during the first 7 days, and that anxiety should be considered as a "warning sign" in critically ill patients.