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Aneurysm clinical trials

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NCT ID: NCT02880059 Recruiting - Comorbidities Clinical Trials

Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms

IESA
Start date: June 2016
Phase: N/A
Study type: Observational

Patients with intracerebral aneurysm will be screened for sleep apnea using out of center polysomnography/polygraphy. Baseline blood pressure and medication will be assessed. Patients will be followed for up to 5 years to examine the increase in aneurysm size, rupture rate and changes in medication.

NCT ID: NCT02879175 Active, not recruiting - Clinical trials for Intracranial Aneurysms

Patients' Follow-up After Subarachnoid Haemorrhage Caused by Ruptured Intracranial Aneurysms

FUSAC
Start date: September 8, 2016
Phase:
Study type: Observational

After endovascular treatment of the intracranial aneurysm, recanalization may occur, with a risk of recurrent subarachnoid haemorrhage or long-term angiographic recurrences of aneurysms. Few data exist on patients' long-term follow-up after subarachnoid haemorrhage caused by ruptured intracranial aneurysms.

NCT ID: NCT02878967 Recruiting - Aneurysm Clinical Trials

Standardized Long Term Follow-up of Patients After Endovascular Embolization of a Brain Aneurysm

ANENDOVASC
Start date: November 25, 2015
Phase:
Study type: Observational

The time-frame and the follow-up elements after embolization of brain aneurysm are not standardized. Therefore, few reliable follow-up data are available for these patients. This study aims at collecting standardized long term data for these patients, in order to assess the occurence of aneurysm recanalization and particularly those requiring another intervention on the aneurysm.

NCT ID: NCT02876263 Completed - Clinical trials for Coronary Artery Disease

Noninvasive Neuromonitoring of Surgery of the Thoracic Aorta

Start date: September 2007
Phase: N/A
Study type: Observational

The aim of this prospective, explorative study of noninvasive neuromonitoring was to search potential and practical methods associated with neurological outcome in the perioperative and immediate postoperative setting of surgery of the thoracic aorta. These methods include abbreviated EEG monitoring, near-infrared spectroscopy, transcranial Doppler ultrasound and biochemical markers associated with neuronal damage.

NCT ID: NCT02875444 Completed - Clinical trials for Abdominal Aortic Aneurysm

Measurement of Maximum Diameter of Native Abdominal Aortic Aneurysm by Angio-CT

AAA-angioCT
Start date: January 2013
Phase: N/A
Study type: Observational

Screening for an abdominal aortic aneurysm, monitoring its growth and evaluation of its risk of rupture are based on the measure of its maximum diameter. The abdominal aortic aneurysm's treatment to prevent its rupture is recommended from a threshold of 50-55 mm in men and of 45-50 mm in women. The importance of this measure for patient management justify a specific and homogeneous protocol of measure. However, the diversity of methods of measuring the maximum diameter with scanner and ultrasound was shown. The impact of various angio-CT based measures of maximum AAA diameter, and the impact of reproducibility limits on the decision to operate have never been investigated.

NCT ID: NCT02875262 Recruiting - Clinical trials for Subarachnoid Hemorrhage

Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial

DASH
Start date: December 2, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Aneurysmal subarachnoid hemorrhage (SAH) is a form of stroke in which secondary neurological deterioration is an important cause of mortality and morbidity. These secondary changes, so called delayed cerebral ischemia (DCI), are caused by lysis of erythrocytes which can react to form iron, an toxic substance to the brain. Iron chelators remove the excess of iron and are standard care in iron-overloaded patients. Deferoxamine (DFO) an chelator has not been evaluated in SAH patients. This study evaluates the safety of deferoxamine in SAH patients.

NCT ID: NCT02869464 Recruiting - Clinical trials for Abdominal Aortic Aneurysm

UVA Brain and Aortic Aneurysm Study

BAAS
Start date: April 2014
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this study is to examine the percentage of patients who present with abdominal aortic aneurysms (AAA) will also have intracranial aneurysms (IA) and conversely; to examine the percentage of patients who present with intracranial aneurysms will also have abdominal aortic aneurysms.

NCT ID: NCT02867501 Completed - Vascular Diseases Clinical Trials

Venous Distension in Patients With Aneurysmatic Arterial Disease

Start date: May 2016
Phase: N/A
Study type: Observational

The aim of the study is to assess if venous distension in patients with aneurysmatic arteriopathy is higher compared to patients with peripheral arterial occlusive disease (PAOD) and in controls.

NCT ID: NCT02866812 Completed - Clinical trials for Intracranial Aneurysm

Prevalence and Factors Associated With the Occurrence of Depression Six Months After an Endovascular Treatment of Intracranial Aneurysm

DEP-AIC
Start date: March 17, 2016
Phase: N/A
Study type: Interventional

During the last decade, the embolization has become the treatment of choice for ruptured intracranial aneurysms, to improve the neurological outcome of patients. At the same time, for his safety, she also became the technique allowing prophylactic treatment of unruptured intracranial aneurysms discovered incidentally during imaging exams. Regarding patients with ruptured intracranial aneurysms, patients who survive often have a reduced quality of life while one in two has a good neurological outcome after embolization. Depression, anxiety and fatigue, whose the psycho-social impact is important, are often cited. This description has often been done without considering the realized type of treatment (surgery or embolization) and mostly of neurological and functional status of the patient remotely (disability or not in daily activities). Regarding patients with unruptured intracranial aneurysms, they are mostly asymptomatic and embolization is programmed. They would present an cognitive impairment in one case in five at 1 month of treatment. If depression, fatigue and difficult return to working life are logically found in patients with severe sequelae (disability in daily activities) of their ruptured intracranial aneurysms, the question arises for patients with a ruptured intracranial aneurysms with a favorable evolution and for asymptomatic patients with unruptured intracranial aneurysms. A precise status of these populations is necessary, especially as the discovery and treatment of their intracranial aneurysms is often early (between 40 and 60 years) and that their good neurological status should allow "a priori" to return easily at the active life.

NCT ID: NCT02864940 Terminated - Clinical trials for Subarachnoid Hemorrhage

Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients

MASH
Start date: June 2016
Phase: N/A
Study type: Interventional

The study aim is to determine if periodic online cognitive exercises (Lumosity) improve memory function in ruptured cerebral aneurysm patients with disabling baseline memory deficits within the first 24 months after rupture. Half of the subjects will be randomized to use Lumosity-designed online cognitive exercises and half will serve as an active control group performing online crossword puzzles.