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Intracranial Aneurysm clinical trials

View clinical trials related to Intracranial Aneurysm.

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NCT ID: NCT03494608 Not yet recruiting - Clinical trials for Intracranial Aneurysm

Evaluation of Postoperative Cognitive Function, Anxiety, Depression and Quality of Life in Patients With Unruptured Intracranial Aneurysms

Start date: April 2018
Phase:
Study type: Observational

This prospective single-center cohort study aims to identify the incidence of cognitive dysfunction after unruptured aneurysm operation and explore the influencing factors. The primary end point is the cognitive dysfunction at 6 months after operation.The features of cognitive function, mental status, neurological function recovery, and quality of life of patients with unruptured intracranial aneurysms at different time points would be analyzed.

NCT ID: NCT03493035 Completed - Clinical trials for Middle Cerebral Artery Aneurysm

Risk Factors for Occurrence of the Middle Cerebral Artery Aneurysm

MCAA
Start date: June 16, 2015
Phase:
Study type: Observational [Patient Registry]

The aim of the research was to evaluate independent risk factors for the presence of middle cerebral artery aneurysm. Hemodynamic factors play the most important role in rupture aneurysm according hemodynamic theory. Geometry of division can influence flow blood. Division of the middle cerebral artery with or without aneurysm were analized using Mimisc software.

NCT ID: NCT03462433 Not yet recruiting - Clinical trials for Unruptured Intracranial Aneurysms

Treatment of Ruptured Intracranial Aneurysms in China.

Start date: May 1, 2018
Phase: N/A
Study type: Observational

Ruptured intracranial aneurysms is currently a common disease that seriously affects human health and quality of life due to its high morbidity,high mortality and high disability. At present,Ruptured intracranial aneurysms are treated with craniotomy clipping and interventional embolization ,but for ruptured wide-neck intracranial aneurysms, the treatment of craniotomy clipping and coiling embolization are not effective.With the improvement of endovascular treatment materials and techniques, three dimensional coil basket technique, double microcatheter technique, balloon assisted ONYX embolization, simple stent covered aneurysm neck, balloon or stent assisted neck remodeling and coil embolization are used in endovascular treatment of ruptured wide-neck intracranial aneurysms. The treatment methods are different in the intervention effect of ruptured wide-neck intracranial aneurysms, for example, the complications of interventional therapy are lower than craniotomy clipping,but the rate of well functional outcome (mRS ≤2) differed significantly by 3 months follow-up (65.0% vs.75.0%), and there is not standard of treatment in different parts of ruptured wide-neck intracranial aneurysms in our country, the choice of interventional therapy or craniotomy clipping are different in different clinical centers; on the other hand, there are serious problems in the treatment of ruptured wide-neck intracranial aneurysms, because without the relevant guidelines of diagnosis and treatment of ruptured wide-neck intracranial aneurysms, different clinical centers will cause excessive treatment of ruptured wide-neck intracranial aneurysms, not only bring unreasonable utilization of medical resources, but also cause the subject's life and property to be threatened. The patients with ruptured wide-neck intracranial aneurysms(n=1084) and unruptured intracranial aneurysms(n=300) were included in prospective cohort study, after interventional therapy and craniotomy clipping, setting fixed time for postoperative follow-up, the clinical data and image data were recorded, the safety, efficacy and economic benefits of interventional treatment and craniotomy clipping were compared, providing strategies for the standardized treatment of ruptured wide-neck intracranial aneurysms.

NCT ID: NCT03423290 Recruiting - Clinical trials for Intracranial Aneurysm

Safety and Efficacy Analysis of FRED™/FRED™Jr Embolic Device in Aneurysm Treatment

Start date: November 23, 2017
Phase: N/A
Study type: Observational

A prospective, multicenter, observational evaluation of the safety and efficacy of the FRED® device in the treatment of intracranial aneurysms

NCT ID: NCT03408379 Recruiting - Clinical trials for Intracranial Aneurysms

Impact of Platelet Activation in Intracranial Aneurysm Rupture Risk - PLAQRAN

PLAQRAN
Start date: December 20, 2017
Phase: N/A
Study type: Observational

Sub arachnoid hemorrhage consecutive to intracranial aneurysm rupture is a devastating disease. Predictors of intracranial aneurysm rupture are limited and focus mainly on size and location. Platelet activation may have a deleterious role on aneurysm rupture. The assumption is that patients with ruptured intracranial aneurysm will present a higher rate of platelet activation compared to patients with non ruptured aneurysms.

NCT ID: NCT03383666 Not yet recruiting - Clinical trials for Unruptured Wide-neck Intracranial Aneurysms

A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm

NAPA
Start date: May 5, 2018
Phase: Phase 3
Study type: Interventional

This is a prospective, multi-center, non-randomized clinical evaluation utilizing the PulseRider® Aneurysm Neck Reconstruction Device.

NCT ID: NCT03379714 Not yet recruiting - Clinical trials for Ruptured and Unruptured Intracranial Aneurysms

Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System

Start date: January 1, 2018
Phase: N/A
Study type: Observational [Patient Registry]

Flow disruption is a new endovascular approach for treatment of both ruptured and unruptured intracranial aneurysms, which involves placement of an endosaccular device (WEB) which modifies the blood flow at the level of the neck and induces intraaneurysmal thrombosis. The WEB was designed to treat wide-neck bifurcation aneurysms. This observational study will collect data about the routine practice in one center of using the WEB in ruptured and unruptured intracranial aneurysms. The primary objective is to evaluate its efficacy by assessing the anatomic outcome during follow-up.

NCT ID: NCT03359252 Recruiting - Headache Clinical Trials

Headache After Coil Embolization for Unruptured Intracranial Aneurysms

Start date: December 26, 2017
Phase: N/A
Study type: Interventional

Perform a prospective cohort study to compare the incidence and severity of headache between non-stent assisted coiling and stent assisted coiling of unruptured intracranial aneurysms.

NCT ID: NCT03355534 Recruiting - Aneurysm Cerebral Clinical Trials

Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery

DACA
Start date: January 5, 2018
Phase: N/A
Study type: Interventional

Dexmedetomidine induces analgesic and sedative effects and is reported to decrease agitation during emergence after general anesthesia in various surgeries. For patients undergoing cranial aneurysm surgeries, a calm anesthesia and emergence is important. In this study, the investigatorstend to observe the effect of dexmedetomidine on maintenance and recovery of patients undergoing cranial aneurysm surgeries.

NCT ID: NCT03312725 Recruiting - Clinical trials for Ruptured and Unruptured Intracranial Aneurysms

Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System

Start date: February 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

Flow disruption is a new endovascular approach for treatment of both ruptured and unruptured intracranial aneurysms, which involves placement of an endosaccular device (WEB) which modifies the blood flow at the level of the neck and induces intraaneurysmal thrombosis. The WEB was designed to treat wide-neck bifurcation aneurysms. This observational study will collect data about the routine practice in one center of using the WEB in ruptured and unruptured intracranial aneurysms. The primary objective is to evaluate its efficacy by assessing the anatomic outcome during follow-up.