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Intracranial Aneurysm clinical trials

View clinical trials related to Intracranial Aneurysm.

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NCT ID: NCT03581409 Recruiting - Clinical trials for Endovascular Procedures

Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm

Start date: July 23, 2018
Phase: Phase 4
Study type: Interventional

Perform a randomized comparison study of dual-antiplatelet (aspirin, prasugrel) and triple-antiplatelet (aspirin, clopidogrel, and cilostazol) preparation using P2Y12 assay in patients with high on-treatment platelet reactivity undergoing stent-assisted coil embolization for an unruptured intracranial aneurysm

NCT ID: NCT03553771 Recruiting - Clinical trials for Intracranial Aneurysm

Safety and Efficacy of the LVIS and LVIS JR Devices in the Endovascular Treatment of Intracranial Aneurysms

Start date: February 7, 2018
Phase:
Study type: Observational

A French, multicenter, prospective, observational, "real life" assessment of the safety and efficacy of LVIS and LVIS JR devices in the treatment of intracranial aneurysms

NCT ID: NCT03550638 Recruiting - Clinical trials for Intracranial Aneurysms

Coil System(Ton-bridgeMT) for Endovascular Embolization of Cranial Aneurysms

Start date: March 31, 2018
Phase: N/A
Study type: Interventional

The study is a prospective, multi-center, randomized, open, parallel positive control, non-inferiority trial. Patients are randomized 1:1 to either Coil System(Ton-bridgeMT) or Axium Detachable Coil(Medtronic). The purpose of this study is to assess the safety and effectiveness of the Coil System(Ton-bridgeMT) in the treatment of intracranial aneurysms.

NCT ID: NCT03504436 Active, not recruiting - Clinical trials for Intracranial Aneurysm

Endovascular Treatment of Wide Neck Intracranial Aneurysms With the LEO + Stent : The LEO + II Cohort Study

Start date: March 15, 2015
Phase:
Study type: Observational [Patient Registry]

This is a prospective, multicenter, single-arm observational study to evaluate the efficacy and the morbi-mortality of LEO + in patients with wide neck intracranial aneurysms (fusiform, saccular or dissecting), ruptured or not ruptured.

NCT ID: NCT03494608 Not yet recruiting - Clinical trials for Intracranial Aneurysm

Evaluation of Postoperative Cognitive Function, Anxiety, Depression and Quality of Life in Patients With Unruptured Intracranial Aneurysms

Start date: May 2018
Phase:
Study type: Observational

This prospective single-center cohort study aims to identify the incidence of cognitive dysfunction after unruptured aneurysm operation and explore the influencing factors. The primary end point is the cognitive dysfunction at 6 months after operation.The features of cognitive function, mental status, neurological function recovery, and quality of life of patients with unruptured intracranial aneurysms at different time points would be analyzed.

NCT ID: NCT03493035 Completed - Clinical trials for Middle Cerebral Artery Aneurysm

Risk Factors for Occurrence of the Middle Cerebral Artery Aneurysm

MCAA
Start date: June 16, 2015
Phase:
Study type: Observational [Patient Registry]

The aim of the research was to evaluate independent risk factors for the presence of middle cerebral artery aneurysm. Hemodynamic factors play the most important role in rupture aneurysm according hemodynamic theory. Geometry of division can influence flow blood. Division of the middle cerebral artery with or without aneurysm were analized using Mimisc software.

NCT ID: NCT03462433 Not yet recruiting - Clinical trials for Unruptured Intracranial Aneurysms

Treatment of Ruptured Intracranial Aneurysms in China.

Start date: May 1, 2018
Phase: N/A
Study type: Observational

Ruptured intracranial aneurysms is currently a common disease that seriously affects human health and quality of life due to its high morbidity,high mortality and high disability. At present,Ruptured intracranial aneurysms are treated with craniotomy clipping and interventional embolization ,but for ruptured wide-neck intracranial aneurysms, the treatment of craniotomy clipping and coiling embolization are not effective.With the improvement of endovascular treatment materials and techniques, three dimensional coil basket technique, double microcatheter technique, balloon assisted ONYX embolization, simple stent covered aneurysm neck, balloon or stent assisted neck remodeling and coil embolization are used in endovascular treatment of ruptured wide-neck intracranial aneurysms. The treatment methods are different in the intervention effect of ruptured wide-neck intracranial aneurysms, for example, the complications of interventional therapy are lower than craniotomy clipping,but the rate of well functional outcome (mRS ≤2) differed significantly by 3 months follow-up (65.0% vs.75.0%), and there is not standard of treatment in different parts of ruptured wide-neck intracranial aneurysms in our country, the choice of interventional therapy or craniotomy clipping are different in different clinical centers; on the other hand, there are serious problems in the treatment of ruptured wide-neck intracranial aneurysms, because without the relevant guidelines of diagnosis and treatment of ruptured wide-neck intracranial aneurysms, different clinical centers will cause excessive treatment of ruptured wide-neck intracranial aneurysms, not only bring unreasonable utilization of medical resources, but also cause the subject's life and property to be threatened. The patients with ruptured wide-neck intracranial aneurysms(n=1084) and unruptured intracranial aneurysms(n=300) were included in prospective cohort study, after interventional therapy and craniotomy clipping, setting fixed time for postoperative follow-up, the clinical data and image data were recorded, the safety, efficacy and economic benefits of interventional treatment and craniotomy clipping were compared, providing strategies for the standardized treatment of ruptured wide-neck intracranial aneurysms.

NCT ID: NCT03423290 Recruiting - Clinical trials for Intracranial Aneurysm

Safety and Efficacy Analysis of FRED™/FRED™Jr Embolic Device in Aneurysm Treatment

Start date: November 23, 2017
Phase:
Study type: Observational

A prospective, multicenter, observational evaluation of the safety and efficacy of the FRED® device in the treatment of intracranial aneurysms

NCT ID: NCT03408379 Recruiting - Clinical trials for Intracranial Aneurysms

Impact of Platelet Activation in Intracranial Aneurysm Rupture Risk - PLAQRAN

PLAQRAN
Start date: December 20, 2017
Phase:
Study type: Observational

Sub arachnoid hemorrhage consecutive to intracranial aneurysm rupture is a devastating disease. Predictors of intracranial aneurysm rupture are limited and focus mainly on size and location. Platelet activation may have a deleterious role on aneurysm rupture. The assumption is that patients with ruptured intracranial aneurysm will present a higher rate of platelet activation compared to patients with non ruptured aneurysms.

NCT ID: NCT03383666 Not yet recruiting - Clinical trials for Unruptured Wide-neck Intracranial Aneurysms

A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm

NAPA
Start date: July 31, 2018
Phase: Phase 3
Study type: Interventional

This is a prospective, multi-center, non-randomized clinical evaluation utilizing the PulseRider® Aneurysm Neck Reconstruction Device.