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Anemia clinical trials

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NCT ID: NCT04505514 Recruiting - Anemia Clinical Trials

Single Dose Intravenous Iron Isomaltoside in Combination With Oral Iron vs Oral Iron Monotherapy in Patients With Anemia After Postpartum Haemorrhage

IVIronPPH
Start date: August 1, 2020
Phase: Phase 4
Study type: Interventional

The investigator's study is going to compare effectiveness of single dose intravenous iron in combination with oral iron versus oral iron monotherapy in correcting haemoglobin deficit, replenishing iron stores and improving clinical symptoms in women with post-partum anaemia after postpartum hemorrhage without increasing the rate of adverse outcomes.

NCT ID: NCT04502784 Enrolling by invitation - Anemia Clinical Trials

Investigation of Hypophosphataemia Following Intravenous Iron

Start date: October 7, 2019
Phase:
Study type: Observational

Anaemia (low haemoglobin levels) can develop in a number of conditions, including chronic kidney disease (CKD) and intestinal conditions (e.g. inflammatory bowel disease, intestinal failure). Intravenous iron can be given to patients with these conditions to help correct their aneaemia. However, intravenous iron has been associated with the development of low phosphate levels - hypophophosphataemia. The aim of this study is to determine potential causes of hypophosphataemia following administration of intravenous iron.

NCT ID: NCT04502537 Recruiting - Clinical trials for Anemia of Chronic Kidney Disease

Roxadustat for Anemia in Patients With CKD

Start date: February 1, 2021
Phase:
Study type: Observational

A number of RCT studies have shown the safety and effectiveness of oral Roxadustat in the treatment of renal anemia, but there is a lack of evidence from cohort studies. A prospective cohort study is planed to conduct to evaluate the efficacy and safety of Roxadustat for renal anemia in the real world.

NCT ID: NCT04491916 Recruiting - Inflammation Clinical Trials

Iron Therapy in Patients With End-Stage Renal Disease

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

This study will compare the clinical outcome of patients with maintenance dialysis room after changing the iron treatment guidelines from original upper limit with ferritin>500ng/ml, or TSAT>20% to Ferritin> 800ng / ml, or TSAT> 50%.

NCT ID: NCT04490863 Completed - Healthy Clinical Trials

Noninvasive Hemoglobin Repeatability and Reproducibility in a Blood Donation Setting

Start date: July 16, 2020
Phase: N/A
Study type: Interventional

The primary objective of this clinical investigation is to report on the repeatability and reproducibility of SpHb measurements from Rad-67 devices and DCI Mini sensors used to screen prospective blood donors at a donation center.

NCT ID: NCT04486456 Not yet recruiting - Prevalence Clinical Trials

Epidemiological Study on Anemia and Iron Deficiency in Pregnancy in Medical Institutions in Some Areas of China

Start date: August 2020
Phase:
Study type: Observational

The purpose of this study is to describe the prevalence of anemia and iron deficiency in pregnancy through a multi-center, prospective follow-up study . To explore the influence factors of anemia and iron deficiency in pregnancy; to explore the influence of anemia and iron deficiency in pregnancy on maternal and fetal outcomes.

NCT ID: NCT04484857 Completed - Clinical trials for Anemia Associated With End Stage Renal Disease

Study of Roxadustat Conversion in Participants Receiving Stable ESA or as Initial Anemia Treatment in Hemodialysis Participants

ASPEN
Start date: July 22, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and effectiveness of roxadustat dosing regimens among hemodialysis participants converted from erythropoiesis stimulating agent (ESA) therapy or who are ESA-naïve.

NCT ID: NCT04484233 Not yet recruiting - Anemia Clinical Trials

Evaluation of a Clinical Decision Support System for Anemia Management in Pre-operative Care

iAnemia
Start date: September 1, 2020
Phase:
Study type: Observational

Anemia need to be diagnosed and treated, following several guidelines. However, the complexity of these recommendations leads to low compliance and to unnecessary and harmful per- and postoperative blood transfusion. In order to improve practices and regarding the complexity of the guidelines, the latest European Consensus Conference recommends the use of decision support systems for the management of preoperative anemia.

NCT ID: NCT04477850 Active, not recruiting - Clinical trials for Myelodysplastic Syndromes

A Study to Evaluate the Efficacy, Drug Levels and Safety of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in Chinese and Japanese Participants With Ring Sideroblasts Who Require Red Blood Cell Transfusions

Start date: November 30, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of luspatercept (ACE-536) for the treatment of anemia due to Revised International Prognostic Scoring System (IPSS-R) very low, low, or intermediate risk myelodysplastic syndromes (MDS) in Chinese and Japanese participants with ring sideroblasts who require Red Blood Cells (RBC) transfusions.

NCT ID: NCT04475887 Recruiting - Clinical trials for Liver Transplantation

Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation

TRAILER
Start date: July 23, 2020
Phase: Phase 4
Study type: Interventional

The aim of this study is to investigate whether therapy with intravenous iron carboxymaltose in patients with iron deficiency anemia (IDA) listed for orthotopic liver transplantation (OLT) increases hemoglobin concentrations and reduces intraoperative transfusion of packed red blood cells (PRBCs). The investigators hypothesize that therapy with intravenous iron will increase hemoglobin concentrations and reduce intraoperative transfusion of PRBCs in patients with IDA listed for OLT.