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Anemia of Chronic Kidney Disease clinical trials

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NCT ID: NCT06352138 Not yet recruiting - Clinical trials for Anemia of Chronic Kidney Disease

Comparative Study of Two Recombinant Human Erythropoietin Products on Chronic Kidney Disease Patients

ENCASE
Start date: July 2024
Phase: Phase 3
Study type: Interventional

Phase III, multicentre, double-blind, randomised, parallel, equivalence clinical trial to determine the efficacy, safety and immunogenicity of Megalabs® recombinant human alfa epoetin for subcutaneous use, compared to Eprex® (Janssen-Cilag Farmacêutica Ltda.), in the treatment of anaemia in participants with chronic renal disease, dependent on haemodialysis

NCT ID: NCT05900635 Recruiting - Clinical trials for Anemia of Chronic Kidney Disease

Effect of Adding Lactoferrin on Oral Iron on Anemia in Chronic Kidney Disease Patients

Start date: October 1, 2022
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate the effects of adding lactoferrin to the every-other-day oral iron supplementation in iron deficiency anemia and chronic kidney disease patients.

NCT ID: NCT05745883 Recruiting - Clinical trials for Chronic Kidney Diseases

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia

Start date: April 4, 2023
Phase: Phase 1
Study type: Interventional

This Phase 1b study of DISC-0974 will assess the safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney Disease and Anemia.

NCT ID: NCT05699109 Completed - Clinical trials for Chronic Renal Failure

Erythropoiesis Stimulating Agents for Anemia Management in Egyptian Hemodialysis Patients

Start date: January 1, 2021
Phase:
Study type: Observational

This observational study aims to compare long-acting darbepoetin alpha versus short-acting epoetin alpha erythropoietin-stimulating agents in Egyptian hemodialysis patients. The main questions aim to answer are: - What are the effectiveness and safety of long- acting versus short-acting erythropoietin-stimulating agents in Egyptian hemodialysis patients? - What is the cost-effectiveness of long- acting versus short-acting erythropoietin-stimulating agents in Egyptian hemodialysis patients? Participants will be divided into 2 groups; epoetin alfa (short-acting ESA), Eprex group, and darbepoetin alfa (long-acting ESA), Aranesp group for six month study period.

NCT ID: NCT05698420 Completed - Depressive Disorder Clinical Trials

Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients

Start date: March 1, 2020
Phase:
Study type: Observational

In this study, the investigators aimed to observe the effects of medium cut-off dialysis filters and high-flux dialysis filters on malnutrition inflammation score, uremic itching, restless leg syndrome, anemia, and ESA treatment, which are prominent complications in hemodialysis, and routine follow-up parameters.

NCT ID: NCT05544513 Active, not recruiting - Dysbiosis Clinical Trials

Oral Iron Supplementation for Patients With Chronic Kidney Disease

Start date: August 1, 2022
Phase: Phase 2
Study type: Interventional

The hypothesis of this research is that oral iron prescribed in a single dose in alternate day could mitigate the side effects with regard to intestinal microbiota, inflammation, oxidative stress and improve the hematological profile when compared to daily oral iron prescription

NCT ID: NCT05515367 Recruiting - Clinical trials for Chronic Kidney Diseases

A Post Marketing Surveillance to Evaluate the Safety of Desidustat for the Treatment of Anemia in Subjects With Chronic Kidney Disease (CKD).(Real World Evidence Study)

Start date: April 20, 2023
Phase: Phase 4
Study type: Interventional

A Phase 4, 52 week, single arm, multicentre post marketing surveillance to evaluate the safety of Desidustat for the treatment of anemia in subjects with chronic kidney disease (CKD)

NCT ID: NCT05082584 Suspended - Clinical trials for Anemia of Chronic Kidney Disease

Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease Naive to Erythropoiesis-Stimulating Agents

CORRECTION
Start date: January 2025
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of once daily dosing of vadadustat for the treatment of pediatric participants with anemia of chronic kidney disease (CKD) naive to erythropoiesis-stimulating agent (ESA) treatment.

NCT ID: NCT05082571 Suspended - Clinical trials for Anemia of Chronic Kidney Disease

Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease

CONVERSION
Start date: January 2025
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of once daily dosing of vadadustat for the treatment of pediatric participants with anemia of Chronic Kidney Disease (CKD) after conversion from an Erythropoiesis Stimulating Agent (ESA).

NCT ID: NCT04959578 Completed - Clinical trials for Anemia of Chronic Kidney Disease

Comparison of Darbepoetin Alpha and Recombinant Human Erythropoietin for Treatment of Anemia in Children With Chronic Kidney Disease

Start date: February 1, 2018
Phase: Phase 4
Study type: Interventional

The present study was designed to determine whether or not darbepoetin alfa is non-inferior to recombinant human erythropoietin in the treatment of anemia in children with chronic kidney disease stage 3-5 (on or not on dialysis).