Gender Heterogeneity in the Influencing Factors for Cerebral Microbleeds in Acute Ischemic Stroke Patients

Acute Ischemic Stroke Clinical Trial

Official title:

Gender Heterogeneity in the Influencing Factors for Cerebral Microbleeds in Acute Ischemic Stroke Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05882123
• Other study ID #: 20220642
• Status: Completed
• Start date: January 2014
• Est. completion date: December 2015

Study information

• Verified date: May 2023
• Source: The First Hospital of Hebei Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators continuously collected data from 482 AIS inpatients at the Neurology Department of Hebei General Hospital. Both demographic and clinical data were collected from the study subjects. Different head magnetic resonance imaging sequences were used to assess the subjects' CMBs, white matter lesions, and old lacunar infarcts (LI). Various statistical methods, including the t-test, χ2 test, and logistic regression, were used to analyze the gender heterogeneity of the influencing factors for CMBs in AIS patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 482
• Est. completion date: December 2015
• Est. primary completion date: December 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Aged 18 years and older
• Must meet the diagnostic criteria for AIS as presented in the Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2014
• Must be in good physical condition and have the ability to cooperate with MRI examinations
• Must have underwent SWI

Exclusion Criteria:

• MRI contraindications present, such as cardiac pacemaker, cardiac stents, or metal implants
• Head MRI or carotid artery ultrasound suggests the presence of severe stenosis or occlusion in the intracranial or extracranial segments of the cerebral arteries
• Severe comorbid diseases, such as cardiac, pulmonary, hepatic, and renal insufficiencies

Related Conditions & MeSH terms

• Acute Ischemic Stroke
• Cerebral Infarction
• Ischemia
• Ischemic Stroke
• Stroke

Intervention

Other:
• cerebral microbleeds
Whether patients with acute ischemic stroke are complicated by cerebral microbleeds

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Xin Guo

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Comparison of clinical data between AIS patients in CMB and non-CMB groups	Differences in general information between AIS patients in CMB and non-CMB groups	from January 2014 to December 2015
Primary	Comparison of clinical data between male and female AIS patients	Differences in general informationbetween male and female AIS patients	from January 2014 to December 2015
Primary	Comparison of CMB-related characteristics between the male and female AIS patients	Differences in CMB-related characteristics between the male and female AIS patients	from January 2014 to December 2015
Primary	Predictive factor analysis for CMBs in male AIS patients	CMB-related factors in male AIS patients	from January 2014 to December 2015
Primary	Predictive factor analysis for CMBs in female AIS patients	CMB-related factors in female AIS patients	from January 2014 to December 2015