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Acute Coronary Syndrome clinical trials

View clinical trials related to Acute Coronary Syndrome.

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NCT ID: NCT02464397 Recruiting - Clinical trials for Acute Coronary Syndrome

Comparison of Strut Coverage With OPTIMAX Versus SYNERGY Stents

OPTIMAX-OCT
Start date: February 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare vascular healing of the stented segment after deployment of titanium-nitride-oxide coated cobalt-chromium OPTIMAX™ bio-active stent (BAS) and SYNERGY™ everolimus-eluting stent (EES) in patients with acute coronary syndromes requiring percutaneous coronary intervention. Patients treated with BAS will be treated with DAPT for at least 4 weeks after the procedure followed by aspirin alone, while patients in the EES group will be treated with DAPT, at least for 6 months post procedure. In addition, this study will collect initial information about the safety and effectiveness of the BAS in comparison with EES group at 30 days, 6 months, and 12 months.

NCT ID: NCT02459288 Recruiting - Clinical trials for Acute Coronary Syndrome

Platelet Resistance With Ticagrelor or Standard-Dose Clopidogrel Among CKD and ACS Patients

APROVE-CKD
Start date: January 2014
Phase: Phase 4
Study type: Interventional

A 4 week-duration cross-over study on Ticagrelor and Clopidogrel for the Acute Coronary Syndrome (ACS) and Chronic Kidney Disease (CKD) subjects, focusing on the platelet inhibition and safety observation.

NCT ID: NCT02455492 Completed - Stroke Clinical Trials

Factors Associated With Perioperative Outcomes in Non-emergency Surgery

Start date: January 2004
Phase: N/A
Study type: Observational

This epidemiological study investigates the association of recent stroke, acute coronary syndrome or pneumonia and adverse perioperative outcomes following elective non-cardiac and cardiac surgery using routinely collected UK primary and secondary care patient data.

NCT ID: NCT02451293 Completed - Depression Clinical Trials

The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome

MEDACIS
Start date: January 18, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of the study is to investigate whether prophylactic treatment with melatonin has an effect on depressive symptoms. Secondarily melatonin's effect on anxiety, sleep and circadian disturbances will be investigated. The MEDACIS trial is a randomised, placebo-controlled, double-blinded multicenter trial investigating the effect of 25 mg exogenous melatonin (intervention group) against placebo (control group) and the study is designed as a parallel group superiority trial.

NCT ID: NCT02446730 Recruiting - Clinical trials for Myocardial Infarction

Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome

BEAUTY-II
Start date: September 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of 5mg maintenance dose (MD) of prasugrel in patients with acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI) with BiomatrixTM stent.

NCT ID: NCT02438085 Recruiting - Clinical trials for Acute Coronary Syndromes

Prospective Registry of Acute Coronary Syndromes in Ferrara

ARYOSTO
Start date: June 2014
Phase:
Study type: Observational [Patient Registry]

The ARYOSTO has been designed to describe the clinical epidemiology and the current management of acute coronary syndromes (ACS) in the area of Ferrara. Especially, the Authors will evaluate the medical and interventional management of ACS patients admitted to hospitals in the area of Ferrara and receiving coronary artery angiography and percutaneous coronary intervention (PCI) in the hub center of Ferrara (Azienda Ospedaliera Universitaria di Ferrara, Cona (FE), Italy)

NCT ID: NCT02430493 Completed - Clinical trials for Acute Coronary Syndrome (ACS)

Evaluation on the Safety of Ticagrelor Among Chinese ACS Patients

YingLong
Start date: May 28, 2015
Phase: N/A
Study type: Observational [Patient Registry]

The primary objective is to describe the safety and tolerability of ticagrelor, by assessment of adverse events (characteristics, reporting rate, severity, relationship and risk factors), especially the bleeding events as defined in 8.1 and other serious adverse events (SAEs) during 1-year follow up in Chinese acute coronary syndrome (ACS) patients.

NCT ID: NCT02428725 Completed - Clinical trials for Acute Coronary Syndrome

Platelet Reactivity Inhibition Following Ticagrelor Loading Dose and One Year Outcome

Start date: April 2015
Phase: N/A
Study type: Interventional

This study will try to determine if the measure of the platelet reactivity of the patients receiving from the ticagrelor continuation in an acute coronary syndrome handled by coronary angioplasty allows to predict the hemorrhagic risk.

NCT ID: NCT02420899 Recruiting - Clinical trials for Acute Coronary Syndrome

Different Doses of Rosuvastatin Therapy on Regression of Critical Coronary Atherosclerosis in ACS Patients

Start date: April 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether Rosuvastatin 10mg/d or 20mg/d for 36 weeks can regress critical coronary atherosclerosis as determined by IVUS imaging in Chinese Acute Coronary Syndrome (ACS) patients.

NCT ID: NCT02420808 Completed - Clinical trials for Coronary Artery Disease

An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study

PHAETHON
Start date: March 2012
Phase: N/A
Study type: Observational

A nationwide registry of patients with acute coronary disease to evaluate epidemiological patient characteristics, medical management, implementation of invasive strategy, patient outcome and impact on quality of life in Greece.