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Wound Surgical clinical trials

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NCT ID: NCT06371430 Completed - Wounds and Injuries Clinical Trials

Bone Bioactive Liquid Efficiency in Improving Dental Implant Osteointegration Oral Soft Tissue Hellingand Oral Surgery

BBLIS
Start date: April 14, 2021
Phase: N/A
Study type: Interventional

The investigators implanted 264 Galaxy TS implants (with or without BBL) in 33 patients across both jaws. Implant stability and osseointegration were assessed using Initial Stability Quotient (ISQ) measurements, computed tomography (CBCT) scans and pain evaluations at various intervals post-surgery. Further, implant surfaces were examined using scanning electron microscopy (SEM) and atomic force microscopy (AFM). In vitro studies evaluated the efficacy of BBL on dental pulp pluripotent stem cells (DPPSCs) osteogenesis, and inflammatory factor modulation in human macrophages.

NCT ID: NCT06309368 Recruiting - Clinical trials for Surgical Site Infection

Ostomy Primary Closure With 0.1% Betaine/0.1% Polyhexanide Wound Irrigation Compared to Pursestring Closure

Start date: March 14, 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare two types of closure in patients with ostomies that are ready for closure. The main questions it aims to answer are: 1. Surgical site infection rates 2. Patient quality of life 3. Time to wound healing Participants will undergo either complete ostomy wound closure after washing out the wound with Prontosan, or their ostomy wound will be closed using the Pursestring method, where the wound will be left partially open and allowed to heal from the inside out. Researchers will compare these two groups' outcomes (questions to be answered) as listed above.

NCT ID: NCT06220344 Completed - Wound Infection Clinical Trials

Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.

Start date: December 2, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other co-morbidities like Diabetes, Anemia, etc. which can make the results biased. The main questions it aims to answer are: - Do the iodine solutions are enough to counter the infections caused by resistant strains of bacteria? - What is the efficacy and efficiency of honey dressing in wound care? Participants will be tasked to - Ensure strict follow-up in the hospital dressing room - Half of the participants will apply common iodine solution dressing and the other half will be applied honey dressing. Researchers will compare Iodine dressing (Control group) with Honey dressing (Experimental group) to see if Honey dressing is better in the prevention of post-surgery wound infection and if it is cost-efficient and its efficacy.

NCT ID: NCT06025253 Not yet recruiting - Wound Infection Clinical Trials

PINTA - Prophylactic Incisional Negative Pressure Therapy for Major Amputations

PINTA
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. This study is taking place to investigate if Negative Pressure Wound Therapy (NPWT) dressings reduces Surgical Site Infections, post surgical complications and improves scar appearance compared to standard dressings.

NCT ID: NCT05977816 Recruiting - Wound Infection Clinical Trials

PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds

PROPEL-2
Start date: July 14, 2023
Phase: N/A
Study type: Interventional

Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. This study is taking place to investigate if Negative Pressure Wound Therapy (NPWT) dressings reduces Surgical Site Infections, post surgical complications and improves scar appearance compared to standard dressings.

NCT ID: NCT05744024 Enrolling by invitation - Virtual Reality Clinical Trials

Non-pharmacological Pain Care During Complex Wound Care Procedures

Start date: November 17, 2022
Phase: N/A
Study type: Interventional

The main objective of this study is to evaluate the effect on pain and both Virtual Reality and Music Therapy as add-on therapy during wound care at the surgical wards in adults.

NCT ID: NCT04887480 Suspended - Abdomen, Acute Clinical Trials

Direct Resuscitation of the Open Peritoneum

SH DROP
Start date: May 14, 2021
Phase: N/A
Study type: Interventional

The DROP trial evaluates two ways of treating patients whose abdomens are left open after their abdominal surgery. The current standard of care at Sanford is for patients to have their wound covered with a sterile dressing connected to a vacuum with suction, which removes fluid from the abdomen. In this trial, we are evaluating the benefits of adding dialysis fluid to the abdomen periodically, prior to suctioning it out with the vacuum system. This trial will show if the addition of this fluid lowers the risk of complications and death, and allows the surgeon to close the abdomen sooner

NCT ID: NCT04865952 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

NCT ID: NCT04743375 Recruiting - Wound Heal Clinical Trials

Clinical Efficacy of Silk Sericin Dressing With Collagen for Split-thickness Skin Graft Donor Site Treatment

Start date: February 2021
Phase: N/A
Study type: Interventional

To examine the efficacy and safety of sericin dressing with collagen in STSG donor site treatment comparing with Bactigras®. Around 30 patients will be enrolled in this study.

NCT ID: NCT04453319 Recruiting - Wound Infection Clinical Trials

Efficacy of Negative Pressure Wound Closure Therapy by PICO System in Prevention of Complications of Femoral Artery Exposure

Start date: January 31, 2020
Phase: N/A
Study type: Interventional

Evaluate negative pressure wound closure therapy by PICO system in Prevention of complications of femoral artery exposure.