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Wound Surgical clinical trials

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NCT ID: NCT06371430 Completed - Wounds and Injuries Clinical Trials

Bone Bioactive Liquid Efficiency in Improving Dental Implant Osteointegration Oral Soft Tissue Hellingand Oral Surgery

BBLIS
Start date: April 14, 2021
Phase: N/A
Study type: Interventional

The investigators implanted 264 Galaxy TS implants (with or without BBL) in 33 patients across both jaws. Implant stability and osseointegration were assessed using Initial Stability Quotient (ISQ) measurements, computed tomography (CBCT) scans and pain evaluations at various intervals post-surgery. Further, implant surfaces were examined using scanning electron microscopy (SEM) and atomic force microscopy (AFM). In vitro studies evaluated the efficacy of BBL on dental pulp pluripotent stem cells (DPPSCs) osteogenesis, and inflammatory factor modulation in human macrophages.

NCT ID: NCT06220344 Completed - Wound Infection Clinical Trials

Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection.

Start date: December 2, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the wound healing in the participants who underwent the clean surgical procedure, by applying honey dressing and common Iodine solution dressing, participants will have no other co-morbidities like Diabetes, Anemia, etc. which can make the results biased. The main questions it aims to answer are: - Do the iodine solutions are enough to counter the infections caused by resistant strains of bacteria? - What is the efficacy and efficiency of honey dressing in wound care? Participants will be tasked to - Ensure strict follow-up in the hospital dressing room - Half of the participants will apply common iodine solution dressing and the other half will be applied honey dressing. Researchers will compare Iodine dressing (Control group) with Honey dressing (Experimental group) to see if Honey dressing is better in the prevention of post-surgery wound infection and if it is cost-efficient and its efficacy.

NCT ID: NCT04865952 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

NCT ID: NCT04276129 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part II

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the influence of the post-surgical chlorhexidine indication in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues. The main hypothesis is that the post-surgical use of chlorhexidine affects the gene expression and the celular behavior in the early wound healing process of the soft oral tissues.

NCT ID: NCT04202822 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part I

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the present study is to observe and compare -through a biomolecular analysis- the differences in the gene expression and cellular behavior in the early wound healing process -24 hours after injury- between the following three oral tissues: alveolar mucosa, buccal gingiva and palatal tissue. The main hypothesis is that there is a difference in the gene expression and in the cellular behaviour between the three oral tissues studied and this difference can be observed at 24 hours post-injury.

NCT ID: NCT03880331 Completed - Wound Heal Clinical Trials

Prospective Randomized Clinical Trial Comparing Outcomes of Secondary Intention Wound Care Methods

Start date: December 3, 2019
Phase: N/A
Study type: Interventional

This is a randomized controlled trial which is designed to determine whether aggressive and frequent debridement of an acute post-surgical wound shortens healing time.