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Vulvar Cancer clinical trials

View clinical trials related to Vulvar Cancer.

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NCT ID: NCT04663412 Recruiting - Vulvar Cancer Clinical Trials

Indocyanine Green Fluorescence Imaging, Sentinel Lymph Node Mapping in Patients With Vulvar Cancer

Start date: July 9, 2020
Phase: N/A
Study type: Interventional

The potential of the administration of indocyanine green (ICG) allows the execution of SLN biopsy, avoiding the multiple administrations of radiocolloid in the pre-operative phase, painful for the patient, elimination, and exposure to radioactivity. Therefore, while requiring standardization of the methodology and a large-scale application, this procedure could open a new surgical management perspective in patients with early-stage vulvar cancer.

NCT ID: NCT04430699 Recruiting - Vulvar Cancer Clinical Trials

Cisplatin+Pembrolizumab+RT in Vulvar Cancer

Start date: July 29, 2020
Phase: Phase 2
Study type: Interventional

This research is being done to see how well the combination of a standard of care drug, investigational drug, and radiation therapy work against unresectable vulvar squamous cell carcinoma. This research study involves the following: - Cisplatin (standard of care drug) - Pembrolizumab (investigational drug) - Radiation Therapy (standard of care intervention)

NCT ID: NCT04425291 Completed - Cervical Cancer Clinical Trials

Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Start date: May 28, 2020
Phase: Phase 3
Study type: Interventional

The study will evaluate the immunogenicity and safety of 4-valent and 9-valent HPV recombinant vaccine in Chinese healthy females 20 to 45 years of age.

NCT ID: NCT04422366 Recruiting - Cervical Cancer Clinical Trials

Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Start date: April 28, 2020
Phase: Phase 3
Study type: Interventional

This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 9-valent Human Papillomavirus (Types 6, 11, 16, 18,31,33,45,52 and 58) Recombinant Vaccine (Hansenula Polymorpha) in Chinese Female Subjects Aged 20-45 Years .

NCT ID: NCT04357873 Active, not recruiting - Clinical trials for Head and Neck Squamous Cell Carcinoma

Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations

PEVOsq
Start date: October 28, 2020
Phase: Phase 2
Study type: Interventional

Interventional study evaluating the efficacy of an immunotherapy (pembrolizumab) in combination with a targeted therapy (vorinostat) in patient with recurrent and/or metastatic squamous cell carcinoma (localisations : head and neck, lung, cervix, anus, vulva, and penis)

NCT ID: NCT04188535 Recruiting - Prostate Cancer Clinical Trials

Serial MRI Scans During Radiation Therapy

RELAY
Start date: January 15, 2020
Phase: N/A
Study type: Interventional

This is a phase 1 study to determine the feasibility and utility of using serial magnetic resonance imaging (MRI) to assess treatment response during and after radiation therapy (standard of care cancer treatment) for participants with advanced esophageal cancer, glioblastoma, prostate cancer, vulvar cancer or pediatric glioma. The research study procedures include three MRI scans (one before, one during, and one after standard of care cancer radiation therapy) for participants with advanced esophageal cancer, glioblastoma, prostate cancer, vulvar cancer or pediatric glioma. The research study procedures include: - Screening for eligibility - Three MRI scans

NCT ID: NCT04152512 Active, not recruiting - Quality of Life Clinical Trials

Quality of Life, Unmet Needs and Satisfaction With Care After Vulvar Cancer

PROVE
Start date: August 29, 2019
Phase:
Study type: Observational

The aim of this prospective, longitudinal Swedish multi-center study is to assess the quality of life, treatment-related morbidity, unmet needs and satisfaction with care after treatment for vulvar cancer, evaluated by a validated questionnaire.

NCT ID: NCT04141449 Recruiting - Breast Cancer Clinical Trials

A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation

Potlako+
Start date: November 18, 2020
Phase: Phase 2
Study type: Interventional

This study evaluates whether the Potlako+ intervention of community education, clinical provider support, and patient navigation can improve access to cancer case for patients presenting with symptoms of cancer. Half of communities will receive the Potlako+ intervention, while the other communities will continue to receive standard programs.

NCT ID: NCT04122235 Recruiting - Ovarian Cancer Clinical Trials

The Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology Study

LETSGO
Start date: November 18, 2019
Phase: N/A
Study type: Interventional

This study compares traditional follow-up of gynaecological cancer patients to an alternative follow-up model. In the alternative follow-up model the patients will meet a nurse at every second consultation. The nurse will focus on psychosocial health and educate the patients in the use of a study specific smartphone-application.

NCT ID: NCT04105465 Terminated - Vulvar Cancer Clinical Trials

Study to Evaluate the Role of PlasmaJet in Patients Undergoing Groin Node Dissection for Vulval Cancer

Start date: July 2013
Phase: N/A
Study type: Interventional

Surgery for vulvar cancer involves removal of the central tumour as well as groin node dissection as indicated depending on the stage of tumour. Groin node dissection is associated with significant complications including lymphorrea, lymphocyst formation, wound breakdown as well as long term complications including lymphedema. This study has been designed with each patient acting as their own control to investigate if using the PlasmaJet during surgery is associated with a reduction in the above mentioned complications.