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Virus Diseases clinical trials

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NCT ID: NCT05226949 Completed - Neonatal Sepsis Clinical Trials

Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection

Start date: January 1, 2022
Phase:
Study type: Observational

This study seeks to identify and test host RNA expression profiles in context to protein biomarkers in dried blood spot samples as novel diagnostic markers of neonatal herpes simplex virus infection and to improve the understanding of the pathogenesis of the disease.

NCT ID: NCT05212480 Completed - SARS-CoV2 Infection Clinical Trials

Evaluation of the Efficacy and Safety of Zinc in Viral Infections

VIZIR
Start date: February 15, 2022
Phase: N/A
Study type: Interventional

The main objective of the clinical study is to evaluate the efficacy of Zinc supplementation in non-critically ill Covid-19 patients..

NCT ID: NCT05198401 Completed - COVID-19 Clinical Trials

The Impact of the Previous Exposure to Covid-19 Virus Infection on the Outcome of ICSI Cycles

Start date: August 1, 2020
Phase:
Study type: Observational [Patient Registry]

Whilst the global COVID-19 pandemic is still evolving and there are many unknowns about the long-term effects of the virus on fertility and pregnancy, we found ourselves in need to offer some evidence-based guidance, that's why we decided to go for this study, to evaluate the relation of the covid-19 and the outcome of IVF/ICSI cycles. we found that there is no clear evidence that the previous exposure to Covid-19 virus infection can affect the outcome of ICSI cycles significantly.

NCT ID: NCT05175482 Completed - Health Behavior Clinical Trials

Health Belief Model Based Education on Human Papilloma Virus Infection and Vaccination

Start date: December 30, 2021
Phase: N/A
Study type: Interventional

To evaluate impact of Health Belief Model Based Education on Human Papilloma Virus Infection and Vaccination among University Students

NCT ID: NCT05166421 Completed - Clinical trials for Corona Virus Disease

Study to Evaluate Pharmacokinetic Comparability Between AZD7442 Co-formulation (AZD8895 + AZD1061) vs AZD8895 and AZD1061 Individually in Adult Healthy Participants

Start date: November 30, 2021
Phase: Phase 1
Study type: Interventional

The study will assess pharmacokinetic (PK) comparability between different formulations of AZD7442, which is a combination of two individual monoclonal antibodies (mAbs), AZD8895 and AZD1061.

NCT ID: NCT05151614 Completed - COVID-19 Pandemic Clinical Trials

Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection

Start date: April 1, 2021
Phase: Phase 1
Study type: Interventional

The study included 2 arms Colchicine group: Colchicine + standard therapy of COVID-19 Control group: Standard therapy of COVID-19

NCT ID: NCT05130398 Completed - Ebola Virus Disease Clinical Trials

Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon

EBOLAPED
Start date: April 9, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

LA rVSVΔG-ZEBOV-GP -02-PED is a Phase 1/2, randomized, controlled open label trial. The LA rVSVΔG-ZEBOV-GP -02-PED trial aims primarily to assess the clinical significance of shedding of the rVSV RNA following vaccination with the rVSVΔG-ZEBOV-GP vaccine in children. The vaccine doses of ≥7.8 x 107 pfu will be evaluated and compared to vaccination with varicella vaccine as a control. In addition, the closest contact persons of the vaccinees will be monitored for possible transmission of the viral vaccine vector. The study will enroll children of two age groups living in Lambaréné, Gabon. Children will be followed-up for 12 months post vaccination. The 1-2 closest contact persons of each participant will be involved in the monitoring of rVSV transmission. They will be followed until day 56 post- vaccination of their children/ sibling.

NCT ID: NCT05090475 Completed - Viral Infection Clinical Trials

Implementation of Academic Detailing Interventions on Prescribing of Antimicrobial Drugs in Primary Health Care

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

World increase in mortality from consequences of antimicrobial resistance (AMR) represents a significant public health problem. Irrational prescribing of antimicrobial drugs (AMD) in general population is one of the main causes of development AMR. This is also contributed by fact that up to 90% of total antimicrobial consumption in Europe is related to the general population. Problem of AMR has been recognized by World Health Organization and Council of European Union, which support the establishment of the antimicrobial stewardship team (A-team). A-team provides co-ordinated interventions that promote rational use of AMD. To date, no study has been carried out in which A-team from hospital environment goes to primary health care for the purpose of rationalization prescribing of AMD by primary health care practitioners. Project for implementation of hospital A-team in primary health care in Koprivnica-Križevci County was initiated using academic detailing method aimed at rationalization of the consumption of AMD.

NCT ID: NCT05078554 Completed - Clinical trials for Papilloma Viral Infection

HPV and Male Homosexuality in General Practice?

HPV
Start date: May 27, 2021
Phase:
Study type: Observational

The main objective of this study is to find out whether young MSM (men who have sex with men) believe it is important for their GP to be informed of their sexual orientation, in order to improve their clinical, especially with HPV vaccination. The secondary objective is to analyze the state of knowledge about the HPV vaccine and the value of HPV vaccine in this target population.

NCT ID: NCT05074953 Completed - Virus Diseases Clinical Trials

Post-COVID-19 Monitoring in Routine Health Insurance Data

POINTED
Start date: August 1, 2021
Phase:
Study type: Observational

The SARS-CoV-2 infection was in 2020 responsible for new disease related chronic conditions which have been referred to as Post-COVID. To date it is still unknown how common this condition is and which symptoms are related to it. The aim of the study is to monitor the onset of these conditions in a large observational study consisting of German health insurance data.