Hepatitis B Infection Clinical Trial
Official title:
Nucleoside Analogue in Late Preganancy to Prevent Vertical Transmission of Hepatitis B Virus
To explore the antiviral effect of nucleoside analogue in late pregnancy and the safety of the antiviral drug to fetus.To establish the best therapy strategy to pregnant women with high level of HBV DNA.
Telbivudine and Lamivudine,a preganancy category B medication,reduces HBV DNA and normalizes serum ALT in chronic hepatitis B patients with few adverse effects.Two aspects on the drug use in pregnancy will be evaluated prospectively in this study. ;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04704024 -
Reducing Vertical Transmission of Hepatitis B in Africa
|
Phase 3 | |
| Active, not recruiting |
NCT02143401 -
Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors
|
Phase 1 | |
| Completed |
NCT00371150 -
Effect of Entecavir in Blacks/African Americans and Hispanics With Chronic Hepatitis B Virus (HBV) Infection
|
Phase 4 | |
| Active, not recruiting |
NCT03519113 -
HBV-associated Liver Transplant(LT) Patients by IV Injecting GC1102
|
Phase 2/Phase 3 | |
| Recruiting |
NCT06368479 -
Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Site Settings
|
N/A | |
| Completed |
NCT01488526 -
Tenofovir in Late Pregnancy to Prevent Vertical Transmission of Hepatitis B Virus
|
Phase 4 | |
| Terminated |
NCT02826018 -
A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection
|
Phase 1 | |
| Completed |
NCT01970254 -
Widespread vs. Selective Screening for Hepatitis B Infection Prior to Chemotherapy
|
||
| Completed |
NCT00489099 -
A Research Study to Test Safety, Tolerability, and Immunogenicity of a Recombinant Hepatitis B Vaccine Manufactured With an Upgrade to the Production Process (V232-054)
|
Phase 3 | |
| Recruiting |
NCT03476083 -
Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission
|
Phase 4 | |
| Recruiting |
NCT03865966 -
Hepatitis B Virus Infection After Liver Transplantation in Children
|
||
| Completed |
NCT03627507 -
Non Inferiority Trial of Locally Manufactured 'Hepa-B' Vaccine in Bangladesh.
|
Phase 2/Phase 3 | |
| Completed |
NCT02443233 -
Evaluation of Paternal, Maternal and Obstetric Factors Leading to the Hepatitis B Immunization Failure in Hong Kong
|
N/A | |
| Completed |
NCT00841477 -
An Hepatitis B Vaccine Model for HIV Vaccine Trials in Drug Users
|
Phase 3 | |
| Terminated |
NCT03887702 -
Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors
|
Phase 3 | |
| Completed |
NCT02304315 -
A Phase 2 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in HBV-related Liver Transplant Recipients
|
Phase 2 | |
| Active, not recruiting |
NCT05117541 -
Social-environmental, Psychosocial, Behavioral, Clinical and Biological Drivers of Disparities in Liver Disease Progression Among Korean American With Chronic Hepatitis B Infection
|
||
| Not yet recruiting |
NCT06368466 -
A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites
|
N/A |